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D7A343

- D7A343_STAND

UniProt

D7A343 - D7A343_STAND

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Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB 9113)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei128 – 1281Substrate; in homodimeric partnerUniRule annotation
Binding sitei178 – 1781SubstrateUniRule annotation
Active sitei180 – 1801Proton acceptorUniRule annotation
Binding sitei182 – 1821SubstrateUniRule annotation
Metal bindingi206 – 2061Magnesium; via carbamate groupUniRule annotation
Metal bindingi208 – 2081MagnesiumUniRule annotation
Metal bindingi209 – 2091MagnesiumUniRule annotation
Active sitei298 – 2981Proton acceptorUniRule annotation
Binding sitei299 – 2991SubstrateUniRule annotation
Binding sitei331 – 3311SubstrateUniRule annotation
Sitei338 – 3381Transition state stabilizerUniRule annotation
Binding sitei383 – 3831SubstrateUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSNOV639283:GCS4-435-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunitUniRule annotation
Gene namesi
Name:cbbLUniRule annotation
Ordered Locus Names:Snov_0428Imported
OrganismiStarkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB 9113)Imported
Taxonomic identifieri639283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeStarkeya
ProteomesiUP000006633: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei206 – 2061N6-carboxylysineUniRule annotation

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD7A343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000230831.
KOiK01601.
OMAiFTQDWAS.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01338. RuBisCO_L_type1.
InterProiIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D7A343-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNAIDKTASA DKPRSRYSAG VMEYRKMGYW QPDYEPKDTD VIALFRVTPQ
60 70 80 90 100
DGVDPIEASA AVAGESSTAT WTVVWTDRLT ACDKYRAKCY RVDPVPNSPG
110 120 130 140 150
SWFAYIAYDL DLFEPGSISN LSASIIGNVF GFKPLKALRL EDMRLPVAYV
160 170 180 190 200
KTFDGPATGI VVERERLDKF GRPLLGATVK PKLGLSGRNY GRVVYEALKG
210 220 230 240 250
GLDFTKDDEN INSQPFMHWR ERFLYCMEAV NKAQASTGEI KGTYLNVTAG
260 270 280 290 300
TMEDMYERAD FAKSLGSNIV MIDLVIGYTA IQSMAKWARR NDMILHLHRA
310 320 330 340 350
GHSTYTRQKS HGVSFRVIAK WMRLAGVDHI HAGTVVGKLE GDPHTTKGYY
360 370 380 390 400
DICRDDFVPQ NLAHGVFFDQ DWASTRKLMP VASGGIHAGQ MHQLIDLLGE
410 420 430 440 450
DVVLQFGGGT IGHPMGIQAG ATANRVALEC MILARNEGRD ILAEGPDILN
460 470 480
EAARHCMPLK QALETWKDVT FNYSSTDTPD FVPQATAAE
Length:489
Mass (Da):54,138
Last modified:August 10, 2010 - v1
Checksum:iF62FCB0F0878F040
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002026 Genomic DNA. Translation: ADH87761.1.
RefSeqiYP_003692380.1. NC_014217.1.

Genome annotation databases

EnsemblBacteriaiADH87761; ADH87761; Snov_0428.
GeneIDi9331485.
KEGGisno:Snov_0428.
PATRICi38253389. VBIStaNov45716_0429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002026 Genomic DNA. Translation: ADH87761.1 .
RefSeqi YP_003692380.1. NC_014217.1.

3D structure databases

ProteinModelPortali D7A343.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADH87761 ; ADH87761 ; Snov_0428 .
GeneIDi 9331485.
KEGGi sno:Snov_0428.
PATRICi 38253389. VBIStaNov45716_0429.

Phylogenomic databases

HOGENOMi HOG000230831.
KOi K01601.
OMAi FTQDWAS.

Enzyme and pathway databases

BioCyci SNOV639283:GCS4-435-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01338. RuBisCO_L_type1.
InterProi IPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB 9113Imported.

Entry informationi

Entry nameiD7A343_STAND
AccessioniPrimary (citable) accession number: D7A343
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3