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Protein
Submitted name:

Cytoplasmic alpha-amylase

Gene

HMPREF0837_11165

Organism
Streptococcus pneumoniae serotype A19 (strain TCH8431)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi103Calcium 1UniRule annotation1
Metal bindingi197Calcium 1UniRule annotation1
Metal bindingi203Calcium 1UniRule annotation1
Metal bindingi205Calcium 2UniRule annotation1
Active sitei234NucleophileUniRule annotation1
Metal bindingi238Calcium 1; via carbonyl oxygenUniRule annotation1
Active sitei264Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSPNE525381-HMP:GTVK-1197-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytoplasmic alpha-amylaseImported (EC:3.2.1.1Imported)
Gene namesi
Ordered Locus Names:HMPREF0837_11165Imported
OrganismiStreptococcus pneumoniae serotype A19 (strain TCH8431)Imported
Taxonomic identifieri525381 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000009083 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD6ZS04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 392AamyInterPro annotationAdd BLAST389

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.
OMAiVLNHKMG.

Family and domain databases

InterProiView protein in InterPro
IPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR006046. Alpha_amylase.
IPR006047. Glyco_hydro_13_cat_dom.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiView protein in SMART
SM00642. Aamy. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

D6ZS04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNQTLMQYF EWYLPHDGQH WTRLAENAPH LAHLGISHVW MPPAFKATNE
60 70 80 90 100
KDVGYGVYDL FDLGEFNQKG TVRTKYGFKE DYLQAIQALK AQGIQPMADV
110 120 130 140 150
VLNHKAAADH REAFQVIEVD PVDRTVELGE PFTINGWTSF TFDGRQDTYN
160 170 180 190 200
GFHWHWYHFT GTDYDAKRSK SGIYLIQGDN KGWANEELVD NENGNYDYLM
210 220 230 240 250
YADLDFKHPE VIQNIYDWAD WFMETTGVAG FRLDAVKHID SFFMRNFIRD
260 270 280 290 300
MKEKYGDDFY VFGEFWNPDK EANLDYLEKT EEHFDLVDVR LHQNLFEASQ
310 320 330 340 350
AGANYDLRGI FTDSLVELKP DKAVTFVDNH DTQRGQALES TVEEWFKPAA
360 370 380 390 400
YALILLRQDG LPCVFYGDYY GISGQYAQED FKEILDRLLA IRKDLAYGEQ
410 420 430 440 450
NDYFDHANCI GWVRSGAENQ SPIAVLISND QENSKSMFVG QEWTNQTFVD
460 470 480
LLGNHQGQVT IDEEGYGQFP VSARSVSVWA VNTI
Length:484
Mass (Da):55,918
Last modified:August 10, 2010 - v1
Checksum:i4E90A450A90EFB8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001993 Genomic DNA. Translation: ADI69393.1.
RefSeqiWP_001181066.1. NC_014251.1.

Genome annotation databases

EnsemblBacteriaiADI69393; ADI69393; HMPREF0837_11165.
KEGGisnc:HMPREF0837_11165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001993 Genomic DNA. Translation: ADI69393.1.
RefSeqiWP_001181066.1. NC_014251.1.

3D structure databases

ProteinModelPortaliD6ZS04.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADI69393; ADI69393; HMPREF0837_11165.
KEGGisnc:HMPREF0837_11165.

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.
OMAiVLNHKMG.

Enzyme and pathway databases

BioCyciSPNE525381-HMP:GTVK-1197-MONOMER.

Family and domain databases

InterProiView protein in InterPro
IPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR006046. Alpha_amylase.
IPR006047. Glyco_hydro_13_cat_dom.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiView protein in SMART
SM00642. Aamy. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD6ZS04_STRP0
AccessioniPrimary (citable) accession number: D6ZS04
Entry historyiIntegrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 7, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.