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Protein
Submitted name:

Aminotransferase AlaT

Gene

HMPREF0837_12263

Organism
Streptococcus pneumoniae serotype A19 (strain TCH8431)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. L-alanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

BioCyciSPNE525381:GH2H-2329-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Aminotransferase AlaTImported (EC:2.6.1.2Imported)
Gene namesi
Ordered Locus Names:HMPREF0837_12263Imported
OrganismiStreptococcus pneumoniae serotype A19 (strain TCH8431)Imported
Taxonomic identifieri525381 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000009083: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD6ZPE5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000223042.
KOiK14260.
OMAiQRNRTWE.
OrthoDBiEOG6X9MJ6.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

D6ZPE5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MKEYNKSSKL EHVAYDIRGP VLEEAMRMRA NGEKILRLNT GNPAEFGFTA
60 70 80 90 100
PDEVIHDLIM NARDSEGYSN SKGIFSARKA IMQYCQLKKF PNVDIDDIYL
110 120 130 140 150
GNGVSELIVM SMQGLLDNGD EVLVPMPDYP LWTAAVSLAG GNAVHYICDE
160 170 180 190 200
AVEWYPDIDD IKSKITSNTK AIVLINPNNP TGALYPKELL LEIIEIARQN
210 220 230 240 250
DLIIFADEIY DRMVMDGHVH TPVASLASDV FCVSMNGLSK SHRIAGFRVG
260 270 280 290 300
WMVLSGPKTH VKGYIEGLNM LSNMRLCSNV LAQQVVQTSL GGHQSVDELL
310 320 330 340 350
LPGGRIYEQR NFIYNAIQDI PGLSAVKPKA GLYIFPKIDR NMYRIDDDEQ
360 370 380 390 400
FVLDFLKQEK VLLVHGRGFN WQEPDHFRIV YLPRVDELAQ IQEKMTRFLK

QYRR
Length:404
Mass (Da):45,731
Last modified:August 10, 2010 - v1
Checksum:i3C4EF45C73332927
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001993 Genomic DNA. Translation: ADI70491.1.
RefSeqiYP_003725705.1. NC_014251.1.

Genome annotation databases

EnsemblBacteriaiADI70491; ADI70491; HMPREF0837_12263.
GeneIDi9345553.
KEGGisnc:HMPREF0837_12263.
PATRICi38266265. VBIStrPne36006_2241.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001993 Genomic DNA. Translation: ADI70491.1.
RefSeqiYP_003725705.1. NC_014251.1.

3D structure databases

ProteinModelPortaliD6ZPE5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADI70491; ADI70491; HMPREF0837_12263.
GeneIDi9345553.
KEGGisnc:HMPREF0837_12263.
PATRICi38266265. VBIStrPne36006_2241.

Phylogenomic databases

HOGENOMiHOG000223042.
KOiK14260.
OMAiQRNRTWE.
OrthoDBiEOG6X9MJ6.

Enzyme and pathway databases

BioCyciSPNE525381:GH2H-2329-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A catalog of reference genomes from the human microbiome."
    Nelson K.E., Weinstock G.M., Highlander S.K., Worley K.C., Creasy H.H., Wortman J.R., Rusch D.B., Mitreva M., Sodergren E., Chinwalla A.T., Feldgarden M., Gevers D., Haas B.J., Madupu R., Ward D.V., Birren B.W., Gibbs R.A., Methe B.
    , Petrosino J.F., Strausberg R.L., Sutton G.G., White O.R., Wilson R.K., Durkin S., Giglio M.G., Gujja S., Howarth C., Kodira C.D., Kyrpides N., Mehta T., Muzny D.M., Pearson M., Pepin K., Pati A., Qin X., Yandava C., Zeng Q., Zhang L., Berlin A.M., Chen L., Hepburn T.A., Johnson J., McCorrison J., Miller J., Minx P., Nusbaum C., Russ C., Sykes S.M., Tomlinson C.M., Young S., Warren W.C., Badger J., Crabtree J., Markowitz V.M., Orvis J., Cree A., Ferriera S., Fulton L.L., Fulton R.S., Gillis M., Hemphill L.D., Joshi V., Kovar C., Torralba M., Wetterstrand K.A., Abouellleil A., Wollam A.M., Buhay C.J., Ding Y., Dugan S., FitzGerald M.G., Holder M., Hostetler J., Clifton S.W., Allen-Vercoe E., Earl A.M., Farmer C.N., Liolios K., Surette M.G., Xu Q., Pohl C., Wilczek-Boney K., Zhu D.
    Science 328:994-999(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TCH8431Imported.

Entry informationi

Entry nameiD6ZPE5_STRP0
AccessioniPrimary (citable) accession number: D6ZPE5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: January 7, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.