D6ZMP4 (D6ZMP4_STRP0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exo-alpha-sialidase EMBL ADI70158.1
EC=3.2.1.18 EMBL ADI70158.1

Gene names

Name:	nanB
Ordered Locus Names:	HMPREF0837_11930

Organism

Streptococcus pneumoniae serotype A19 (strain TCH8431) [Complete proteome] [HAMAP] EMBL ADI70158.1

Taxonomic identifier

525381 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	697 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase EMBL ADI70158.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D6ZMP4 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: A2C2CF53B871D3E2	FASTA	697	77,587
	10 20 30 40 50 60 MNKRGLYSKL GISVVGISLL MGVPTLIHAN ELNYGQLSIS PIFQGGSYQL NNKSIDISPL 70 80 90 100 110 120 LLDKLSGESQ TVVMKFKADE PNSLQALFGL SNSKAGFKNN YFSIFMRDSG EIGVEIRDAQ 130 140 150 160 170 180 KGINYLFSRP ASLWGKHKGQ AVENTLVFVS DSKDKTYTMY VNGMEVFSET VDTFLPISNI 190 200 210 220 230 240 NGIDKATLGA VNREGKEHYL AKGSIGEISL FNKAISDQEV STIPLSNPFQ LIFQSGDSTQ 250 260 270 280 290 300 ANYFRIPTLY TLSSGRVLSS IDACYGGTHD SKSKINIATS YSDDNGKTWS EPIFAMKFND 310 320 330 340 350 360 YEEQLVYWPR DNKLKNSQIS GSASFIDSSI VEDKKSGKTI LLADVMPAGI GNNNANKADS 370 380 390 400 410 420 GFKEINGHYY LKLKKNGDND FRYTVRENGV VYDETTNKPT NYTINDKYEV LEGGKSLTVE 430 440 450 460 470 480 QYSVDFDSGS LREKHNGKQV PMNVFYKDSL FKVTPTNYIA MTTSQNRGES WEQFKLLPPF 490 500 510 520 530 540 LGEKHNGTYL CPGQGLALKS SNRLIFATYT SGELTYLISD DSGQTWKKSS ASIPFKNATA 550 560 570 580 590 600 EAQMVELRDG VIRTFFRTTT GKIAYMTSRD SGETWSEVSY IDGIQQTSYG TQVSAIKYSQ 610 620 630 640 650 660 LIDGKEAVIL STPNSRSGRK GGQLVVGLVN KEDDSIDWKY HYDIDLPSYG YAYSAITELP 670 680 690 NHHIGVLFEK YDSWSRNELH LSNVVQYIDL EINDLTK

References

[1]

"A catalog of reference genomes from the human microbiome." Nelson K.E., Weinstock G.M., Highlander S.K., Worley K.C., Creasy H.H., Wortman J.R., Rusch D.B., Mitreva M., Sodergren E., Chinwalla A.T., Feldgarden M., Gevers D., Haas B.J., Madupu R., Ward D.V., Birren B.W., Gibbs R.A., Methe B. , Petrosino J.F., Strausberg R.L., Sutton G.G., White O.R., Wilson R.K., Durkin S., Giglio M.G., Gujja S., Howarth C., Kodira C.D., Kyrpides N., Mehta T., Muzny D.M., Pearson M., Pepin K., Pati A., Qin X., Yandava C., Zeng Q., Zhang L., Berlin A.M., Chen L., Hepburn T.A., Johnson J., McCorrison J., Miller J., Minx P., Nusbaum C., Russ C., Sykes S.M., Tomlinson C.M., Young S., Warren W.C., Badger J., Crabtree J., Markowitz V.M., Orvis J., Cree A., Ferriera S., Fulton L.L., Fulton R.S., Gillis M., Hemphill L.D., Joshi V., Kovar C., Torralba M., Wetterstrand K.A., Abouellleil A., Wollam A.M., Buhay C.J., Ding Y., Dugan S., FitzGerald M.G., Holder M., Hostetler J., Clifton S.W., Allen-Vercoe E., Earl A.M., Farmer C.N., Liolios K., Surette M.G., Xu Q., Pohl C., Wilczek-Boney K., Zhu D. Science 328:994-999(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TCH8431.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001993 Genomic DNA. Translation: ADI70158.1.
RefSeq	YP_003725372.1. NC_014251.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADI70158; ADI70158; HMPREF0837_11930.
GeneID	9345194.
KEGG	snc:HMPREF0837_11930.
PATRIC	38265556. VBIStrPne36006_1912.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000285031.
KO	K01186.
OMA	QEVSNIP.
Enzyme and pathway databases
BioCyc	SPNE525381:GH2H-1970-MONOMER.
Family and domain databases
Gene3D	2.120.10.10. 2 hits. 2.40.220.10. 1 hit. 2.60.120.200. 1 hit.
InterPro	IPR002860. BNR_rpt. IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR004124. Glyco_hydro_33_N. IPR011040. Sialidases. IPR023364. Trans_sialidase_dom3. [Graphical view]
Pfam	PF02012. BNR. 1 hit. PF02973. Sialidase. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D6ZMP4_STRP0

Accession

Primary (citable) accession number: D6ZMP4

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 29, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)