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D6ZJD8

- D6ZJD8_MOBCV

UniProt

D6ZJD8 - D6ZJD8_MOBCV

Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

    Catalytic activityi

    Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei72 – 721Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. uracil DNA N-glycosylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. base-excision repair Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    GlycosidaseUniRule annotationSAAS annotationImported, Hydrolase

    Keywords - Biological processi

    DNA damage, DNA repairUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMCUR548479:GH17-539-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
    Short name:
    UDGUniRule annotation
    Gene namesi
    Name:ungUniRule annotationImported
    Ordered Locus Names:HMPREF0573_10518Imported
    OrganismiMobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis)Imported
    Taxonomic identifieri548479 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesActinomycineaeActinomycetaceaeMobiluncus/Falcivibrio groupMobiluncus
    ProteomesiUP000006742: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the uracil-DNA glycosylase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229528.
    KOiK03648.
    OMAiIDWDLNE.

    Family and domain databases

    Gene3Di3.40.470.10. 1 hit.
    HAMAPiMF_00148. UDG.
    InterProiIPR018085. Ura-DNA_Glyclase_AS.
    IPR002043. Ura_DNA_glycsylse.
    IPR005122. Uracil-DNA_glycosylase-like.
    [Graphical view]
    PANTHERiPTHR11264. PTHR11264. 1 hit.
    PfamiPF03167. UDG. 1 hit.
    [Graphical view]
    SMARTiSM00986. UDG. 1 hit.
    [Graphical view]
    SUPFAMiSSF52141. SSF52141. 1 hit.
    TIGRFAMsiTIGR00628. ung. 1 hit.
    PROSITEiPS00130. U_DNA_GLYCOSYLASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6ZJD8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQTGEERGGL ERIMSPDWAQ VMAPVEGQIH AMGDFLRAEL AAGRGYFPAG    50
    ENVFHAFQYP LERVKVLIVG QDPYPTPGHA MGLSFSVMSG TEIPRSLVNI 100
    FKELHQDLGL PLPTSGDLRP WAEQGVMLLN RALTVQPGKP ASHRGRGWEA 150
    ITEFAIRELA NHHAAQGLPL VAILWGADAR RTKEFMPHVP CLESVHPSPL 200
    SASRGFFGSR PFSRANELLV AQSGQPVDWR LP 232
    Length:232
    Mass (Da):25,485
    Last modified:August 10, 2010 - v1
    Checksum:iE3853EBA2A9A9AE1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001992 Genomic DNA. Translation: ADI66837.1.
    RefSeqiYP_003718331.1. NC_014246.1.

    Genome annotation databases

    EnsemblBacteriaiADI66837; ADI66837; HMPREF0573_10518.
    GeneIDi9336169.
    KEGGimcu:HMPREF0573_10518.
    PATRICi38203082. VBIMobCur30313_0504.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001992 Genomic DNA. Translation: ADI66837.1 .
    RefSeqi YP_003718331.1. NC_014246.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI66837 ; ADI66837 ; HMPREF0573_10518 .
    GeneIDi 9336169.
    KEGGi mcu:HMPREF0573_10518.
    PATRICi 38203082. VBIMobCur30313_0504.

    Phylogenomic databases

    HOGENOMi HOG000229528.
    KOi K03648.
    OMAi IDWDLNE.

    Enzyme and pathway databases

    BioCyci MCUR548479:GH17-539-MONOMER.

    Family and domain databases

    Gene3Di 3.40.470.10. 1 hit.
    HAMAPi MF_00148. UDG.
    InterProi IPR018085. Ura-DNA_Glyclase_AS.
    IPR002043. Ura_DNA_glycsylse.
    IPR005122. Uracil-DNA_glycosylase-like.
    [Graphical view ]
    PANTHERi PTHR11264. PTHR11264. 1 hit.
    Pfami PF03167. UDG. 1 hit.
    [Graphical view ]
    SMARTi SM00986. UDG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52141. SSF52141. 1 hit.
    TIGRFAMsi TIGR00628. ung. 1 hit.
    PROSITEi PS00130. U_DNA_GLYCOSYLASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Mobiluncus curtisii ATCC 43063."
      Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R.
      , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R., Gibbs R.
      Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43063 / DSM 2711 / V125Imported.

    Entry informationi

    Entry nameiD6ZJD8_MOBCV
    AccessioniPrimary (citable) accession number: D6ZJD8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3