D6ZIX6 (D6ZIX6_MOBCV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tufA EMBL ADI66675.1
Synonyms:	tuf HAMAP-Rule MF_00118
Ordered Locus Names:	HMPREF0573_10356 EMBL ADI66675.1

Organism

Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis) [Complete proteome] [HAMAP] EMBL ADI66675.1

Taxonomic identifier

548479 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Actinomycineae › Actinomycetaceae › Mobiluncus/Falcivibrio group › Mobiluncus › Mobiluncus curtisii

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding HAMAP-Rule MF_00118 RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor HAMAP-Rule MF_00118 RuleBase RU000325 EMBL ADI66675.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	85 – 89	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	140 – 143	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	D6ZIX6 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: 91B8D1A4EDA23572	FASTA	398	43,814
	10 20 30 40 50 60 MAQGTYTHDK PHVNVGTIGH VDHGKTTLTA AITKVLADKY PDLPANKFTP FDQVDNAPEE 70 80 90 100 110 120 RQRGITINVS HVEYETPNRH YAHVDAPGHA DYIKNMITGA AQMDGAILVV AATDGPMAQT 130 140 150 160 170 180 KEHILLAKQV GVPSILVALN KCDSSDVDED MLEIVEDEIR DDLEKQGFDR DCPIIHVSAL 190 200 210 220 230 240 KALEGDPEWT KKIEELMEAV DTYIPEPVRD LDKPFLMPIE DVFTITGRGT VVTGRVERGK 250 260 270 280 290 300 LPLNAEVEIV GIRPTQKTTV TGIEMFHKSM DEAYAGENCG LLLRGTKRED VERGQVVCIP 310 320 330 340 350 360 GSVTPHTKFE GKVYILKKDE GGRHKSFYDG YRPQFFFRTT DVTGVIHLPE GTEMVMPGDT 370 380 390 TEISVELIQP IAMEEGLGFA IREGGRTVGS GKVTKIIA

References

[1]

"Complete sequence of Mobiluncus curtisii ATCC 43063." Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R. , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R., Gibbs R. Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43063 / DSM 2711 / V125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001992 Genomic DNA. Translation: ADI66675.1.
RefSeq	YP_003718169.1. NC_014246.1.
3D structure databases
ProteinModelPortal	D6ZIX6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADI66675; ADI66675; HMPREF0573_10356.
GeneID	9335995.
KEGG	mcu:HMPREF0573_10356.
PATRIC	38202740. VBIMobCur30313_0344.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000229290.
KO	K02358.
Enzyme and pathway databases
BioCyc	MCUR548479:GH17-365-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF52540. SSF52540. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D6ZIX6_MOBCV

Accession

Primary (citable) accession number: D6ZIX6

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 29, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)