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D6ZIQ8

- D6ZIQ8_MOBCV

UniProt

D6ZIQ8 - D6ZIQ8_MOBCV

Protein

Alanine racemase

Gene

alr

Organism
Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei41 – 411Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei173 – 1731SubstrateUniRule annotation
    Active sitei310 – 3101Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei358 – 3581Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMCUR548479:GH17-297-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:HMPREF0573_10288Imported
    OrganismiMobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis)Imported
    Taxonomic identifieri548479 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesActinomycineaeActinomycetaceaeMobiluncus/Falcivibrio groupMobiluncus
    ProteomesiUP000006742: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei41 – 411N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD6ZIQ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIAINAVE.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 2 hits.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 2 hits.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6ZIQ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNVDVSQWP VRAVVNLSAY QENLAQMRRF APHSQQMAIV KANAYGHGIE    50
    RMALAALGAG TEWLGVAKAS EAFRLRKYLD KHGVPRDHLV DTPTSAMMRS 100
    RLYQTAAMGL PSATRPRILT WLYVPHTDLL PVVKSEIDIS VSTLDQLDQV 150
    SRACDAAGKR ARLHLKVDTG LCRAGATDED FPVLCKLARA RERAGLVEVS 200
    AVWSHLARAD EDTAAAEAFT KSQLKAFDEA WEVAQEAGLR PQLRHIAATA 250
    GIIWYPESHY DLVRVGISGY GLSPNPEIAS SWQLGVRPVM RLETNVVQVK 300
    RVEKGAAVSY GGEWVAPGPR WLGLLPVGYA DGLHRLAKNR GETWIKGRRA 350
    PIVGRIPMDQ IVVDLGPAVD DTGTSVPCPV EPGELAIIFG DPKDRLLGGI 400
    PGVPALPTAD DWAEWTDTIN YEVITSISPN VPRVYVKDEP ER 442
    Length:442
    Mass (Da):48,376
    Last modified:August 10, 2010 - v1
    Checksum:iBFE7807CEF3DC5AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001992 Genomic DNA. Translation: ADI66607.1.
    RefSeqiWP_013188702.1. NC_014246.1.
    YP_003718101.1. NC_014246.1.

    Genome annotation databases

    EnsemblBacteriaiADI66607; ADI66607; HMPREF0573_10288.
    GeneIDi9335927.
    KEGGimcu:HMPREF0573_10288.
    PATRICi38202608. VBIMobCur30313_0278.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001992 Genomic DNA. Translation: ADI66607.1 .
    RefSeqi WP_013188702.1. NC_014246.1.
    YP_003718101.1. NC_014246.1.

    3D structure databases

    ProteinModelPortali D6ZIQ8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI66607 ; ADI66607 ; HMPREF0573_10288 .
    GeneIDi 9335927.
    KEGGi mcu:HMPREF0573_10288.
    PATRICi 38202608. VBIMobCur30313_0278.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IAINAVE.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci MCUR548479:GH17-297-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 2 hits.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 2 hits.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Mobiluncus curtisii ATCC 43063."
      Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R.
      , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R., Gibbs R.
      Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43063 / DSM 2711 / V125Imported.

    Entry informationi

    Entry nameiD6ZIQ8_MOBCV
    AccessioniPrimary (citable) accession number: D6ZIQ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3