D6ZHB3 (D6ZHB3_MOBCV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribulose-phosphate 3-epimerase PIRNR PIRNR001461
EC=5.1.3.1 PIRNR PIRNR001461

Gene names

Name:	rpe EMBL ADI68021.1
Ordered Locus Names:	HMPREF0573_11702 EMBL ADI68021.1

Organism

Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio vaginalis) [Complete proteome] [HAMAP] EMBL ADI68021.1

Taxonomic identifier

548479 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Actinomycineae › Actinomycetaceae › Mobiluncus/Falcivibrio group › Mobiluncus › Mobiluncus curtisii

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribulose 5-phosphate = D-xylulose 5-phosphate. PIRNR PIRNR001461
Cofactor	Binds 1 divalent metal cation per subunit. Active with Co2+, Mn2+ and Zn2+ By similarity. PIRSR PIRSR001461-2
Sequence similarities	Belongs to the ribulose-phosphate 3-epimerase family. PIRNR PIRNR001461

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR001461
Ligand	Cobalt PIRSR PIRSR001461-2 Manganese PIRSR PIRSR001461-2 Metal-binding PIRSR PIRSR001461-2 Zinc PIRSR PIRSR001461-2
Molecular function	Isomerase PIRNR PIRNR001461 EMBL ADI68021.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW ribulose-phosphate 3-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	140 – 143	4	Substrate binding By similarity PIRSR PIRSR001461-3
	Region	195 – 196	2	Substrate binding By similarity PIRSR PIRSR001461-3
Sites
	Active site	33	1	Proton acceptor By similarity PIRSR PIRSR001461-1
	Active site	173	1	Proton donor By similarity PIRSR PIRSR001461-1
	Metal binding	31	1	Divalent metal cation By similarity PIRSR PIRSR001461-2
	Metal binding	33	1	Divalent metal cation By similarity PIRSR PIRSR001461-2
	Metal binding	64	1	Divalent metal cation By similarity PIRSR PIRSR001461-2
	Metal binding	173	1	Divalent metal cation By similarity PIRSR PIRSR001461-2
	Binding site	8	1	Substrate By similarity PIRSR PIRSR001461-3
	Binding site	64	1	Substrate By similarity PIRSR PIRSR001461-3
	Binding site	175	1	Substrate; via amide nitrogen By similarity PIRSR PIRSR001461-3

Sequences

	Sequence		Length	Mass (Da)
	D6ZHB3 [UniParc]. Last modified August 10, 2010. Version 1. Checksum: 96EE4E32F50217CE	FASTA	220	23,824
	10 20 30 40 50 60 MSLKIYPSVL NCDQMHFAKA LQDIKSADGV HLDIMDNHFV PNLTWGLPTA TAVLNSTRLP 70 80 90 100 110 120 VDAHLMIENP DRWSLEYAKA GCAIVCFHLE ASRAPIRTAD VLHSLGAKVG IALNPATPAS 130 140 150 160 170 180 AIKDILGRFD QVTVMSVEPG FGGQKFIPEV LPKIRQLRAY AEDARLPLDI EVDGGINDDT 190 200 210 220 LPLVLQAGAN VVVAGSYVFK RNPEQAIATL RTIGATDHTH

References

[1]

"Complete sequence of Mobiluncus curtisii ATCC 43063." Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R. , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R., Gibbs R. Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43063 / DSM 2711 / V125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001992 Genomic DNA. Translation: ADI68021.1.
RefSeq	YP_003719515.1. NC_014246.1.
3D structure databases
ProteinModelPortal	D6ZHB3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADI68021; ADI68021; HMPREF0573_11702.
GeneID	9337384.
KEGG	mcu:HMPREF0573_11702.
PATRIC	38205416. VBIMobCur30313_1642.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000259349.
KO	K01783.
Enzyme and pathway databases
BioCyc	MCUR548479:GH17-1754-MONOMER.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR013785. Aldolase_TIM. IPR026019. Ribul_P_3_epim. IPR000056. Ribul_P_3_epim-like. IPR011060. RibuloseP-bd_barrel. [Graphical view]
PANTHER	PTHR11749. PTHR11749. 1 hit.
Pfam	PF00834. Ribul_P_3_epim. 1 hit. [Graphical view]
PIRSF	PIRSF001461. RPE. 1 hit.
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMs	TIGR01163. rpe. 1 hit.
PROSITE	PS01085. RIBUL_P_3_EPIMER_1. 1 hit. PS01086. RIBUL_P_3_EPIMER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D6ZHB3_MOBCV

Accession

Primary (citable) accession number: D6ZHB3

Entry history

Integrated into UniProtKB/TrEMBL:	August 10, 2010
Last sequence update:	August 10, 2010
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)