Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D6ZB81

- D6ZB81_SEGRD

UniProt

D6ZB81 - D6ZB81_SEGRD

Protein

Alanine racemase

Gene

Srot_0353

Organism
Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei138 – 1381SubstrateUniRule annotation
    Active sitei274 – 2741Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei322 – 3221Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSROT640132:GHEU-362-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Srot_0353Imported
    OrganismiSegniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)Imported
    Taxonomic identifieri640132 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeSegniliparaceaeSegniliparus
    ProteomesiUP000002247: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD6ZB81.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIYSHLAL.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6ZB81-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIPAVQATVD HHAIAHNVRL LAQASAPAQV IAVLKANAYG HGAVPVARTA    50
    LAAGAAQIGV ATLAEAFELR QGGIEAPIIA WLHAFDPDEA VAVFAEAIAS 100
    GIELGVSTSS QVRAVAEAAL RADQLAVVAV KVDTGLNRGG FARGEWRKAF 150
    ADLANAEAAG AVQVRGVFSH LANADRPEYR TNAEQARSLR EAVSFARAAG 200
    LAPELVHLAN SPAVLTRPKA LVNELPVFNA TRPGVAVYGL SPIMGRDFGL 250
    IPAMTLTARV GLTKRIHAGD GVSYGHDFVA ASDTTLALLP IGYADGLQRA 300
    LAGKFEVSIG GRRYPGVGRV CMDQVLVDLG PGEPKVREGD TAVLFGPGSD 350
    GEQTADDWAR AAGTINYEIV TQLRGRVQLR HIHQREPVDQ LRHTHHA 397
    Length:397
    Mass (Da):41,666
    Last modified:August 10, 2010 - v1
    Checksum:i98853E8F192AE9DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001958 Genomic DNA. Translation: ADG96840.1.
    RefSeqiWP_013137296.1. NC_014168.1.
    YP_003657671.1. NC_014168.1.

    Genome annotation databases

    EnsemblBacteriaiADG96840; ADG96840; Srot_0353.
    GeneIDi9178387.
    KEGGisrt:Srot_0353.
    PATRICi38246887. VBISegRot51051_0354.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001958 Genomic DNA. Translation: ADG96840.1 .
    RefSeqi WP_013137296.1. NC_014168.1.
    YP_003657671.1. NC_014168.1.

    3D structure databases

    ProteinModelPortali D6ZB81.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADG96840 ; ADG96840 ; Srot_0353 .
    GeneIDi 9178387.
    KEGGi srt:Srot_0353.
    PATRICi 38246887. VBISegRot51051_0354.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IYSHLAL.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci SROT640132:GHEU-362-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578Imported.

    Entry informationi

    Entry nameiD6ZB81_SEGRD
    AccessioniPrimary (citable) accession number: D6ZB81
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3