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Protein

Glutamate decarboxylase

Gene

Srot_0273

Organism
Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSROT640132:GHEU-281-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Srot_0273Imported
OrganismiSegniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)Imported
Taxonomic identifieri640132 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesSegniliparaceaeSegniliparus
ProteomesiUP000002247 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi640132.Srot_0273.

Structurei

3D structure databases

ProteinModelPortaliD6ZB01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

D6ZB01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTDPAYTSW LDLQFQPPAR LGDTSLDADG VARHIHDELM LDGSSRLNLA
60 70 80 90 100
TFVSTWMEPQ AQKLMVEAFD KNMIDKDEYP ATAAIETRCV SIVADLFHAP
110 120 130 140 150
GLDPGDPGTA TGVSTIGSSE AVMLGGLALK WRWRLARERA GASTARPNLV
160 170 180 190 200
LGSNVQVVWE KFCRYFEVEP RYLPMAPGRY TITAEQVREA VDENTIGVVA
210 220 230 240 250
ILGTTFTGEF EPVEQIAQVL DELAASGGPD VKIHVDAASG GFVAPFLHPE
260 270 280 290 300
LRWDFRVPRV ASINVSGHKY GLTYPGVGFV VWRDREQLPE ELIFRVSYLG
310 320 330 340 350
GDMPTFTLNF SRPGNQVIGQ YYNFLRFGRE GYTRIMGALQ HIARWIADEL
360 370 380 390 400
AALPGVRMIA DGSAIPVVAF ALDEELGYDV YALSHALRAG GWQVPAYPMP
410 420 430 440
EGAQGLSVLR IVVREGFSGE LARALVQAVG TAMQELSQGG LKPRKQFMH
Length:449
Mass (Da):49,230
Last modified:August 10, 2010 - v1
Checksum:i7E750A1895EFFEC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001958 Genomic DNA. Translation: ADG96760.1.
RefSeqiWP_013137216.1. NC_014168.1.
YP_003657591.1. NC_014168.1.

Genome annotation databases

EnsemblBacteriaiADG96760; ADG96760; Srot_0273.
KEGGisrt:Srot_0273.
PATRICi38246711. VBISegRot51051_0267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001958 Genomic DNA. Translation: ADG96760.1.
RefSeqiWP_013137216.1. NC_014168.1.
YP_003657591.1. NC_014168.1.

3D structure databases

ProteinModelPortaliD6ZB01.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi640132.Srot_0273.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADG96760; ADG96760; Srot_0273.
KEGGisrt:Srot_0273.
PATRICi38246711. VBISegRot51051_0267.

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.

Enzyme and pathway databases

BioCyciSROT640132:GHEU-281-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578Imported.

Entry informationi

Entry nameiD6ZB01_SEGRD
AccessioniPrimary (citable) accession number: D6ZB01
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 24, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.