Skip Header

Contribute Send feedback
Read comments (?) or add your own

D6Z8J8 (D6Z8J8_SEGRD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase HAMAP-Rule MF_00253
EC=6.1.1.14 HAMAP-Rule MF_00253
Alternative name(s):
Glycyl-tRNA synthetase HAMAP-Rule MF_00253
Gene names
Name:glyQS HAMAP-Rule MF_00253
Ordered Locus Names:Srot_1818
OrganismSegniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578) [Complete proteome] [HAMAP]
Taxonomic identifier640132 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Segniliparaceae › Segniliparus ›

Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glycine to tRNA(Gly) By similarity. HAMAP-Rule MF_00253 SAAS SAAS002315

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00253 SAAS SAAS022961

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00253 SAAS SAAS002315

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00253.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. RuleBase RU003746 HAMAP-Rule MF_00253

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding198 – 2003ATP By similarity HAMAP-Rule MF_00253
Nucleotide binding208 – 2136ATP By similarity HAMAP-Rule MF_00253
Nucleotide binding285 – 2862ATP By similarity HAMAP-Rule MF_00253
Nucleotide binding329 – 3324ATP By similarity HAMAP-Rule MF_00253
Region213 – 2175Substrate binding By similarity HAMAP-Rule MF_00253
Region325 – 3295Substrate binding By similarity HAMAP-Rule MF_00253

Sites

Binding site1031Substrate By similarity HAMAP-Rule MF_00253
Binding site1661Substrate By similarity HAMAP-Rule MF_00253

Sequences

Sequence LengthMass (Da)Tools
D6Z8J8 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 384BB8F62C1F5EEE

FASTA46553,059
        10         20         30         40         50         60 
MASSQKGSVI DAVANLAKRR GLVYPCGEIY GGTKSAWDYG PLGVELKENI KRQWWQSVVT 

        70         80         90        100        110        120 
SRDDVVGLDS SIVLPRQVWV ASGHVEVFND PLVESLITHK RYRADHLVEA YEAKHGHPPP 

       130        140        150        160        170        180 
NGLADIRDPE TGEPGQWTEP RDFNMMLKTY LGPIESEDGL HYLRPETAQG IFVNFANVVT 

       190        200        210        220        230        240 
TARRKPPFGI AQIGKSFRNE ITPGNFIFRT REFEQMEMEF FVEPQTAREW HQHWIDTRLQ 

       250        260        270        280        290        300 
WYVDLGIDPE NLRLYEHPKE KLSHYSDRTV DIEYRFRFQG SEWGELEGVA NRTDFDLSTH 

       310        320        330        340        350        360 
AKHSGADLSY YDQAQDRRYV PYVIEPAAGL TRSLMAFLVD AYAEDEAPNT KGGVDKRTVL 

       370        380        390        400        410        420 
RLDPRLAPVK AAVLPLQKDG GLVAAAKDLA ARLRKRWNID YDETQAIGRR YRRQDEIGTP 

       430        440        450        460 
FCVTVDFESL EDQAVTIRER DTMSQQRVAL DQVAAFLFER LDPGA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001958 Genomic DNA. Translation: ADG98278.1.
RefSeqYP_003659109.1. NC_014168.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADG98278; ADG98278; Srot_1818.
GeneID9179878.
KEGGsrt:Srot_1818.
PATRIC38249932. VBISegRot51051_1853.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000242016.
KOK01880.
OMADLSYFDQ.

Family and domain databases

Gene3D3.40.50.800. 1 hit.
HAMAPMF_00253_B. Gly_tRNA_synth_B.
InterProIPR002314. aa-tRNA-synt_IIb_cons-dom.
IPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR022961. Gly_tRNA_ligase_bac.
IPR002315. tRNA-synt_gly.
[Graphical view]
PANTHERPTHR10745. PTHR10745. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
[Graphical view]
PRINTSPR01043. TRNASYNTHGLY.
SUPFAMSSF52954. Anticodon_bd. 1 hit.
TIGRFAMsTIGR00389. glyS_dimeric. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD6Z8J8_SEGRD
AccessionPrimary (citable) accession number: D6Z8J8
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info