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D6YWZ1 (D6YWZ1_WADCW) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlA3 EMBL ADI38652.1
Synonyms:ddl HAMAP-Rule MF_00047
Ordered Locus Names:wcw_1300 EMBL ADI38652.1
OrganismWaddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044) [Complete proteome] [HAMAP] EMBL ADI38652.1
Taxonomic identifier716544 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesWaddliaceaeWaddlia

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain140 – 358219ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding173 – 22856ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3141Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3281Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3281Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3301Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D6YWZ1 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 13FDB2A51BDE3149

FASTA38041,894
        10         20         30         40         50         60 
MLDLAVLFGG RSIEHEISVI TGLQAILALN PKKYKILPVY FALNGKWYTG DPLLERSFYR 

        70         80         90        100        110        120 
KLPAAYSDLT EITLLPDPSI GGFKDLALNR TYPVDRCLLC FHGQYGEDGC VQGLLELAGL 

       130        140        150        160        170        180 
PYTGSRVLSS ALTMSKSHTK LLLQALNIPC LPHVVVDKQE AVSDLAAVRK KILDTLRYPL 

       190        200        210        220        230        240 
FIKPNHLGSS IGIAKATDKN SLDRALAKVF LYDSAAIIEP YLDNLLEINV SVLEGDPPRS 

       250        260        270        280        290        300 
SAVEIPIASQ EALSYEDKYL KGGAKSTGGS SQGMAGLTRM IDPQDLDLKI KQGVINHALK 

       310        320        330        340        350        360 
AFKELSCSGV CRFDFMLDTS TETLYFNEAN PIPGSLSFYL WDRTEPKLLY SELLDVLIER 

       370        380 
CAHKSALQRS LKKDFGFQAL 

« Hide

References

[1]"The Waddlia genome: a window into chlamydial biology."
Bertelli C., Collyn F., Croxatto A., Ruckert C., Polkinghorne A., Kebbi-Beghdadi C., Goesmann A., Vaughan L., Greub G.
PLoS ONE 5:E10890-E10890(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1470 / WSU 86-1044.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001928 Genomic DNA. Translation: ADI38652.1.
RefSeqYP_003709658.1. NC_014225.1.

3D structure databases

ProteinModelPortalD6YWZ1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI38652; ADI38652; wcw_1300.
GeneID9278279.
KEGGwch:wcw_1300.
PATRIC38314594. VBIWadCho156037_1262.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011593.
KOK01921.

Enzyme and pathway databases

BioCycWCHO716544:GHGA-1300-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD6YWZ1_WADCW
AccessionPrimary (citable) accession number: D6YWZ1
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)