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D6YRY8

- D6YRY8_WADCW

UniProt

D6YRY8 - D6YRY8_WADCW

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Protein

Protein translocase subunit SecY

Gene

secY

Organism
Waddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.UniRule annotation

GO - Biological processi

  1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
  2. protein targeting Source: UniProtKB-HAMAP
  3. protein transport by the Sec complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, TranslocationUniRule annotation, Transport

Enzyme and pathway databases

BioCyciWCHO716544:GHGA-1484-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecYUniRule annotation
Gene namesi
Name:secYUniRule annotationImported
Ordered Locus Names:wcw_1484Imported
OrganismiWaddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044)Imported
Taxonomic identifieri716544 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesWaddliaceaeWaddlia
ProteomesiUP000001505: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. intracellular Source: GOC
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei18 – 3821HelicalUniRule annotationAdd
BLAST
Transmembranei73 – 9321HelicalUniRule annotationAdd
BLAST
Transmembranei121 – 14121HelicalUniRule annotationAdd
BLAST
Transmembranei163 – 18321HelicalUniRule annotationAdd
BLAST
Transmembranei196 – 21621HelicalUniRule annotationAdd
BLAST
Transmembranei231 – 25121HelicalUniRule annotationAdd
BLAST
Transmembranei288 – 30821HelicalUniRule annotationAdd
BLAST
Transmembranei326 – 34621HelicalUniRule annotationAdd
BLAST
Transmembranei386 – 40621HelicalUniRule annotationAdd
BLAST
Transmembranei412 – 43221HelicalUniRule annotationAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the SecY/SEC61-alpha family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

HOGENOMiHOG000080586.
KOiK03076.

Family and domain databases

Gene3Di1.10.3370.10. 1 hit.
HAMAPiMF_01465. SecY.
InterProiIPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiPF00344. SecY. 1 hit.
[Graphical view]
PIRSFiPIRSF004557. SecY. 1 hit.
SUPFAMiSSF103491. SSF103491. 1 hit.
TIGRFAMsiTIGR00967. 3a0501s007. 1 hit.
PROSITEiPS00755. SECY_1. 1 hit.
PS00756. SECY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6YRY8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIQALQRVFS IPELRQKISF TLLMLVVCRI GAFIPVPGIN GEVAIQYLRH
60 70 80 90 100
LTGGEQNLFR MVDTFTGGAF SQMTVIALGV VPYISASIMM QLFTALIPSL
110 120 130 140 150
QREIQENPTL GRRKVNRLTR LVTLILAFIQ SAMFAKYAIQ MNITKPGIIA
160 170 180 190 200
GDLLNIQMFG HPVLFYAVMI FTMTTGTLFL MWIGEQITEN GIGNGMSLII
210 220 230 240 250
TLGIISSFPT AIGMIFQQLN LDSQEAGQLN FAIVAVIMAV FVLVTIGTIL
260 270 280 290 300
IVQGHRRIPL QYARRVVGRK EVQGGNSYIP LKVNYAGVIP VIFASSLLMF
310 320 330 340 350
PATIATFIGQ GTWLESVAMW FRQDRTAYMV MYVGLIIFFT YFWTATQFRP
360 370 380 390 400
DQIASDMKKN GAFIPGIRQG RPTQEYLEHT MNRITLIGAV FLALIAILPT
410 420 430 440 450
ITGRVLGVSQ TISYFFGGTA LLILVGVVLD TMKQIESHLL MKRYEGFMKK

GRARGR
Length:456
Mass (Da):50,748
Last modified:August 10, 2010 - v1
Checksum:i85C3FF5BEC463541
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001928 Genomic DNA. Translation: ADI38833.1.
RefSeqiWP_013182541.1. NC_014225.1.
YP_003709839.1. NC_014225.1.

Genome annotation databases

EnsemblBacteriaiADI38833; ADI38833; wcw_1484.
GeneIDi9278463.
KEGGiwch:wcw_1484.
PATRICi38314956. VBIWadCho156037_1440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001928 Genomic DNA. Translation: ADI38833.1 .
RefSeqi WP_013182541.1. NC_014225.1.
YP_003709839.1. NC_014225.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADI38833 ; ADI38833 ; wcw_1484 .
GeneIDi 9278463.
KEGGi wch:wcw_1484.
PATRICi 38314956. VBIWadCho156037_1440.

Phylogenomic databases

HOGENOMi HOG000080586.
KOi K03076.

Enzyme and pathway databases

BioCyci WCHO716544:GHGA-1484-MONOMER.

Family and domain databases

Gene3Di 1.10.3370.10. 1 hit.
HAMAPi MF_01465. SecY.
InterProi IPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR023201. SecY_su_dom.
[Graphical view ]
PANTHERi PTHR10906. PTHR10906. 1 hit.
Pfami PF00344. SecY. 1 hit.
[Graphical view ]
PIRSFi PIRSF004557. SecY. 1 hit.
SUPFAMi SSF103491. SSF103491. 1 hit.
TIGRFAMsi TIGR00967. 3a0501s007. 1 hit.
PROSITEi PS00755. SECY_1. 1 hit.
PS00756. SECY_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1470 / WSU 86-1044Imported.

Entry informationi

Entry nameiD6YRY8_WADCW
AccessioniPrimary (citable) accession number: D6YRY8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3