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D6YRY8

- D6YRY8_WADCW

UniProt

D6YRY8 - D6YRY8_WADCW

Protein

Protein translocase subunit SecY

Gene

secY

Organism
Waddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
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    Functioni

    The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.UniRule annotation

    GO - Biological processi

    1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
    2. protein targeting Source: UniProtKB-HAMAP
    3. protein transport by the Sec complex Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, TranslocationUniRule annotation, Transport

    Enzyme and pathway databases

    BioCyciWCHO716544:GHGA-1484-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein translocase subunit SecYUniRule annotation
    Gene namesi
    Name:secYUniRule annotationImported
    Ordered Locus Names:wcw_1484Imported
    OrganismiWaddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044)Imported
    Taxonomic identifieri716544 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesWaddliaceaeWaddlia
    ProteomesiUP000001505: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
    Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. intracellular Source: GOC
    3. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membraneUniRule annotation, Cell membrane, Membrane

    Interactioni

    Subunit structurei

    Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei18 – 3821Helical;UniRule annotationAdd
    BLAST
    Transmembranei73 – 9321Helical;UniRule annotationAdd
    BLAST
    Transmembranei121 – 14121Helical;UniRule annotationAdd
    BLAST
    Transmembranei163 – 18321Helical;UniRule annotationAdd
    BLAST
    Transmembranei196 – 21621Helical;UniRule annotationAdd
    BLAST
    Transmembranei231 – 25121Helical;UniRule annotationAdd
    BLAST
    Transmembranei288 – 30821Helical;UniRule annotationAdd
    BLAST
    Transmembranei326 – 34621Helical;UniRule annotationAdd
    BLAST
    Transmembranei386 – 40621Helical;UniRule annotationAdd
    BLAST
    Transmembranei412 – 43221Helical;UniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SecY/SEC61-alpha family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000080586.
    KOiK03076.

    Family and domain databases

    Gene3Di1.10.3370.10. 1 hit.
    HAMAPiMF_01465. SecY.
    InterProiIPR026593. SecY.
    IPR002208. SecY/SEC61-alpha.
    IPR023201. SecY_su_dom.
    [Graphical view]
    PANTHERiPTHR10906. PTHR10906. 1 hit.
    PfamiPF00344. SecY. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004557. SecY. 1 hit.
    SUPFAMiSSF103491. SSF103491. 1 hit.
    TIGRFAMsiTIGR00967. 3a0501s007. 1 hit.
    PROSITEiPS00755. SECY_1. 1 hit.
    PS00756. SECY_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6YRY8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIQALQRVFS IPELRQKISF TLLMLVVCRI GAFIPVPGIN GEVAIQYLRH    50
    LTGGEQNLFR MVDTFTGGAF SQMTVIALGV VPYISASIMM QLFTALIPSL 100
    QREIQENPTL GRRKVNRLTR LVTLILAFIQ SAMFAKYAIQ MNITKPGIIA 150
    GDLLNIQMFG HPVLFYAVMI FTMTTGTLFL MWIGEQITEN GIGNGMSLII 200
    TLGIISSFPT AIGMIFQQLN LDSQEAGQLN FAIVAVIMAV FVLVTIGTIL 250
    IVQGHRRIPL QYARRVVGRK EVQGGNSYIP LKVNYAGVIP VIFASSLLMF 300
    PATIATFIGQ GTWLESVAMW FRQDRTAYMV MYVGLIIFFT YFWTATQFRP 350
    DQIASDMKKN GAFIPGIRQG RPTQEYLEHT MNRITLIGAV FLALIAILPT 400
    ITGRVLGVSQ TISYFFGGTA LLILVGVVLD TMKQIESHLL MKRYEGFMKK 450
    GRARGR 456
    Length:456
    Mass (Da):50,748
    Last modified:August 10, 2010 - v1
    Checksum:i85C3FF5BEC463541
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001928 Genomic DNA. Translation: ADI38833.1.
    RefSeqiYP_003709839.1. NC_014225.1.

    Genome annotation databases

    EnsemblBacteriaiADI38833; ADI38833; wcw_1484.
    GeneIDi9278463.
    KEGGiwch:wcw_1484.
    PATRICi38314956. VBIWadCho156037_1440.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001928 Genomic DNA. Translation: ADI38833.1 .
    RefSeqi YP_003709839.1. NC_014225.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI38833 ; ADI38833 ; wcw_1484 .
    GeneIDi 9278463.
    KEGGi wch:wcw_1484.
    PATRICi 38314956. VBIWadCho156037_1440.

    Phylogenomic databases

    HOGENOMi HOG000080586.
    KOi K03076.

    Enzyme and pathway databases

    BioCyci WCHO716544:GHGA-1484-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3370.10. 1 hit.
    HAMAPi MF_01465. SecY.
    InterProi IPR026593. SecY.
    IPR002208. SecY/SEC61-alpha.
    IPR023201. SecY_su_dom.
    [Graphical view ]
    PANTHERi PTHR10906. PTHR10906. 1 hit.
    Pfami PF00344. SecY. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004557. SecY. 1 hit.
    SUPFAMi SSF103491. SSF103491. 1 hit.
    TIGRFAMsi TIGR00967. 3a0501s007. 1 hit.
    PROSITEi PS00755. SECY_1. 1 hit.
    PS00756. SECY_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1470 / WSU 86-1044Imported.

    Entry informationi

    Entry nameiD6YRY8_WADCW
    AccessioniPrimary (citable) accession number: D6YRY8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3