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D6XU69 (D6XU69_BACIE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Bsel_1849 EMBL ADH99355.1
OrganismBacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) [Complete proteome] [HAMAP] EMBL ADH99355.1
Taxonomic identifier439292 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain138 – 343206ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding171 – 22656ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2971Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3101Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3101Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3121Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D6XU69 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 6E68A6EDF0D4F447

FASTA35940,104
        10         20         30         40         50         60 
MTTKLGLVYG GKSAEHQVSL QTAKAVINAL DFEQYEVHPI YITVTGRWIR GQELTSTIED 

        70         80         90        100        110        120 
ASLLKFEEGK EISPTSLNQS VFPSYESEER PFDIIFPLLH GPNGEDGTIQ GLLEMLDIPY 

       130        140        150        160        170        180 
VGNGVLASSA GMDKVMMKNI YAHAGIRQPA YVWYTRPNYE KDTEAACQHV EEVLGFPCFV 

       190        200        210        220        230        240 
KPANLGSSVG ISKASNRQEL VQAFQTAFDY DRKVIVEEGI DGREVEIAVL GNDEPECSVV 

       250        260        270        280        290        300 
GEIVPKADFY DYKAKYEDNS TGLIIPAEIT DEEYETIKAV AVQSFKALDC SGLVRADFFL 

       310        320        330        340        350 
TKDSTILMNE VNTMPGFTPV SMFPLLWKES GISYPALIEK MIRLGMERYD EKKRIKHTF 

« Hide

References

[1]"Complete sequence of Bacillus selenitireducens MLS10."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Stolz J.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700615 / DSM 15326 / MLS10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001791 Genomic DNA. Translation: ADH99355.1.
RefSeqYP_003699921.1. NC_014219.1.

3D structure databases

ProteinModelPortalD6XU69.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADH99355; ADH99355; Bsel_1849.
GeneID9264423.
KEGGbse:Bsel_1849.
PATRIC38123037. VBIBacSel78655_1962.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011593.
KOK01921.
OMAQIDVIFP.

Enzyme and pathway databases

BioCycBSEL439292:GHLG-1912-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD6XU69_BACIE
AccessionPrimary (citable) accession number: D6XU69
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)