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D6XST1 (D6XST1_BACIE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Malate dehydrogenase HAMAP-Rule MF_00487

EC=1.1.1.37 HAMAP-Rule MF_00487
Gene names
Name:mdh HAMAP-Rule MF_00487
Ordered Locus Names:Bsel_1355 EMBL ADH98867.1
OrganismBacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) [Complete proteome] [HAMAP] EMBL ADH98867.1
Taxonomic identifier439292 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. HAMAP-Rule MF_00487 SAAS SAAS011275

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. HAMAP-Rule MF_00487 SAAS SAAS011275

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 3 family. HAMAP-Rule MF_00487

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding12 – 176NAD By similarity HAMAP-Rule MF_00487
Nucleotide binding123 – 1253NAD By similarity HAMAP-Rule MF_00487

Sites

Active site1801Proton acceptor By similarity HAMAP-Rule MF_00487
Binding site361NAD By similarity HAMAP-Rule MF_00487
Binding site871Substrate By similarity HAMAP-Rule MF_00487
Binding site931Substrate By similarity HAMAP-Rule MF_00487
Binding site1001NAD By similarity HAMAP-Rule MF_00487
Binding site1251Substrate By similarity HAMAP-Rule MF_00487
Binding site1561Substrate By similarity HAMAP-Rule MF_00487

Amino acid modifications

Modified residue1491Phosphoserine By similarity HAMAP-Rule MF_00487

Sequences

Sequence LengthMass (Da)Tools
D6XST1 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: 4B474E2B1A02CF8A

FASTA31133,506
        10         20         30         40         50         60 
MAIKRRKITV VGGGFTGTTT ALMTAQKELG DVVLIDIPKM EDPTKGKALD MMEASPVQGF 

        70         80         90        100        110        120 
DSKITGTSDY KDTAGSDIVV ITAGIPRKPG MSRDDLVSTN AGIMKSVTQE IVKYSPDCYI 

       130        140        150        160        170        180 
IVLTNPVDAM TYTVFKESGF PKNRVIGQSG VLDTARFNTF VAEELNVSVE DVTGFVLGGH 

       190        200        210        220        230        240 
GDDMVPMLRY SFAGGIPLEK LIDKERLEAI VERTRKGGGE IVNLLGNGSA YYAPAASIVQ 

       250        260        270        280        290        300 
MVEAILKDKK RILPTIAYLE GEYGYSDLYL GVPTVIGGDG IEQVFELDLN DDEKAALDKS 

       310 
VASVKKVMEI L 

« Hide

References

[1]"Complete sequence of Bacillus selenitireducens MLS10."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Stolz J.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700615 / DSM 15326 / MLS10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001791 Genomic DNA. Translation: ADH98867.1.
RefSeqYP_003699433.1. NC_014219.1.

3D structure databases

ProteinModelPortalD6XST1.
SMRD6XST1. Positions 5-311.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADH98867; ADH98867; Bsel_1355.
GeneID9263927.
KEGGbse:Bsel_1355.
PATRIC38122005. VBIBacSel78655_1448.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000213794.
KOK00024.
OMAGANSYEA.

Enzyme and pathway databases

BioCycBSEL439292:GHLG-1417-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
HAMAPMF_00487. Malate_dehydrog_3.
InterProIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR011275. Malate_DH_type3.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11540. PTHR11540. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
PRINTSPR00086. LLDHDRGNASE.
SUPFAMSSF56327. SSF56327. 1 hit.
TIGRFAMsTIGR01763. MalateDH_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD6XST1_BACIE
AccessionPrimary (citable) accession number: D6XST1
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: February 19, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)