Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D6XQI2

- D6XQI2_HELPV

UniProt

D6XQI2 - D6XQI2_HELPV

Protein

Alanine racemase

Gene

alr

Organism
Helicobacter pylori (strain v225d)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (10 Aug 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei37 – 371Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei135 – 1351SubstrateUniRule annotation
    Active sitei271 – 2711Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei319 – 3191Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciHPYL637913:GLEV-956-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:HPV225_0962Imported
    OrganismiHelicobacter pylori (strain v225d)Imported
    Taxonomic identifieri637913 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000007088: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei37 – 371N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD6XQI2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiLWQLEAI.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D6XQI2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKRASFVEV NSASLRHNFS AVKSIVPKDA HIMAVVKANA YGVGAIKASE    50
    IFLQEGAHYL GVATLDEALE LRSYFSKTPI LILGYSPNAN ASMLIDNDLS 100
    AMIFSLEQAE VFSQMALKSQ KRLKIHLKID TGMHRLGLEP NFKSIEIIKK 150
    IRALKGLEVE GIFTHLSNAD AKIKTHAKNQ MKAFNAFLEQ LLNQKIEFQY 200
    RHAYNSAGIL SLCNGNENRF LNLYRPGIML YGFYPSNGMK ETCPTILKNV 250
    ISLKAQIVQI RSVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLMRALGN 300
    RIQVAINNQL APLIGKVCMD QCFVKLNNIQ AKEGDEVILF GDKSAKANDA 350
    SEIAALLNTI PYETISTLSK RLERVYI 377
    Length:377
    Mass (Da):41,898
    Last modified:August 10, 2010 - v1
    Checksum:iE1B357975657ACB7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001582 Genomic DNA. Translation: ADI35026.1.
    RefSeqiWP_000917943.1. NC_017355.1.
    YP_005763875.1. NC_017355.1.

    Genome annotation databases

    EnsemblBacteriaiADI35026; ADI35026; HPV225_0962.
    GeneIDi12342553.
    KEGGihpv:HPV225_0962.
    PATRICi43069536. VBIHelPyl5358_0956.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001582 Genomic DNA. Translation: ADI35026.1 .
    RefSeqi WP_000917943.1. NC_017355.1.
    YP_005763875.1. NC_017355.1.

    3D structure databases

    ProteinModelPortali D6XQI2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADI35026 ; ADI35026 ; HPV225_0962 .
    GeneIDi 12342553.
    KEGGi hpv:HPV225_0962.
    PATRICi 43069536. VBIHelPyl5358_0956.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi LWQLEAI.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci HPYL637913:GLEV-956-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: v225dImported.

    Entry informationi

    Entry nameiD6XQI2_HELPV
    AccessioniPrimary (citable) accession number: D6XQI2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 10, 2010
    Last sequence update: August 10, 2010
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3