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D6XPX8 (D6XPX8_HELPV) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=6.3.2.4 EMBL ADI34822.1
Gene names
Ordered Locus Names:HPV225_0746 EMBL ADI34822.1
OrganismHelicobacter pylori (strain v225d) [Complete proteome] [HAMAP] EMBL ADI34822.1
Taxonomic identifier637913 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS011095

Subcellular location

Cytoplasm By similarity SAAS SAAS011095.

Sequence similarities

Contains ATP-grasp domain. SAAS SAAS011095

Sequences

Sequence LengthMass (Da)Tools
D6XPX8 [UniParc].

Last modified August 10, 2010. Version 1.
Checksum: DCF7F0B927861343

FASTA29633,622
        10         20         30         40         50         60 
MHSKYFAQIK EKKLPPLILT CNGLLKNSFL GAKIIELPLV INLVHGGDGE DGKLASLLEF 

        70         80         90        100        110        120 
YRIAFIGPRI EASVLSYNKY LTKLYAKDLG VKALDHVLLN EKNRANALNL IGFNFPFIIK 

       130        140        150        160        170        180 
PSNAGSSLGV SVVKEEKELI YALDGAFEYS KEVLIEPFIQ GVKEYNLAGC KIKKDFCFSY 

       190        200        210        220        230        240 
VEEPNKQEFL DFKQKYLDFS RNKAPKANLS NALEEQLKEN FKKLYNDLFD GALIRCDFFV 

       250        260        270        280        290 
IENEVYLNEI NPIPGSLANY LFDDFKTTLE NLAQSLPKTP KIPIKNSYLL QIQKNK 

« Hide

References

[1]"Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses."
Mane S.P., Dominguez-Bello M.G., Blaser M.J., Sobral B.W., Hontecillas R., Skoneczka J., Mohapatra S.K., Crasta O.R., Evans C., Modise T., Shallom S., Shukla M., Varon C., Megraud F., Maldonado-Contreras A.L., Williams K.P., Bassaganya-Riera J.
J. Bacteriol. 192:3078-3092(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: v225d.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001582 Genomic DNA. Translation: ADI34822.1.
RefSeqYP_005763671.1. NC_017355.1.

3D structure databases

ProteinModelPortalD6XPX8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADI34822; ADI34822; HPV225_0746.
GeneID12342339.
KEGGhpv:HPV225_0746.
PATRIC43069100. VBIHelPyl5358_0742.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000102494.
KOK01921.
OMAHNGLLKN.

Enzyme and pathway databases

BioCycHPYL637913:GLEV-741-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD6XPX8_HELPV
AccessionPrimary (citable) accession number: D6XPX8
Entry history
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: May 14, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)