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D6XJX8

- D6XJX8_TRYB2

UniProt

D6XJX8 - D6XJX8_TRYB2

Protein
Submitted name:

DNA ligase, putative

Gene

Tb927.7.600

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: InterPro

    Keywords - Molecular functioni

    LigaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DNA ligase, putativeImported (EC:6.5.1.1Imported)
    Gene namesi
    ORF Names:Tb927.7.600Imported
    OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
    Taxonomic identifieri999953 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
    ProteomesiUP000008524: Chromosome 7

    Subcellular locationi

    GO - Cellular componenti

    1. kinetoplast Source: GeneDB_Tbrucei

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000258023.
    KOiK01971.
    OMAiLECCHGL.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    InterProiIPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR029319. DNA_ligase_OB.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF01068. DNA_ligase_A_M. 1 hit.
    PF14743. DNA_ligase_OB_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    PROSITEiPS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6XJX8-1 [UniParc]FASTAAdd to Basket

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    MWRISNLWRR PQLTTLPKDP SLFFGVGRPR TPEQVERYHA MKNTTIESAF    50
    PHLAACWVGP SWGTVMLTPH HVAPTCVKSA VWRCSQCLQE FEMSIARFID 100
    QHGTCPLCGK EQRRISSTRN EGPERINGKM SEGDNTDVGI TTSPTDATNE 150
    EDLELEDVNS LRAPRMTHTN YKSVLHSNPE WEGRNILPML AQRWELVAEE 200
    LLHPADTEEQ ESLLVSPKID GIRCLIGYNK SQKKLQFFSR SGILLECCHG 250
    LVPHAMPLFK ADPSLLLDGE LFAPHCGFER LSGLVRRLEK FTTQTTRRKQ 300
    AKLLEYFAFD IMASDQLSSP DAPFSERYRL LKELIPHSGA DRVFDTMKPN 350
    GRRNHQLEKE ELSSRKKIPK LYHVPATLVS PDEVESVLEK ACSQGYEGVI 400
    IRRPKFPYEH GKRSLGLLKY KYMHDAEYRI VDFLPGNGKF EGGLGAFVCE 450
    TSTGIRFNAT PKTTTKRRLE LWAERDRLLG KYLTVQYQEL SSQDVPRFPI 500
    AKCVRGESEK DWL 513
    Length:513
    Mass (Da):58,617
    Last modified:June 28, 2011 - v1
    Checksum:i229080A827159E2C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159437 Genomic DNA. Translation: AAX70312.1.
    CP000070 Genomic DNA. Translation: AAZ12125.1.
    RefSeqiXP_845684.1. XM_840591.1.

    Genome annotation databases

    GeneIDi3658273.
    KEGGitbr:Tb927.7.600.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159437 Genomic DNA. Translation: AAX70312.1 .
    CP000070 Genomic DNA. Translation: AAZ12125.1 .
    RefSeqi XP_845684.1. XM_840591.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3658273.
    KEGGi tbr:Tb927.7.600.

    Phylogenomic databases

    HOGENOMi HOG000258023.
    KOi K01971.
    OMAi LECCHGL.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    InterProi IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR029319. DNA_ligase_OB.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF01068. DNA_ligase_A_M. 1 hit.
    PF14743. DNA_ligase_OB_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    PROSITEi PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    2. "The genome of the African trypanosome Trypanosoma brucei."
      Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
      , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
      Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 927/4 GUTat10.1Imported.
    3. "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
      Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.
      , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: GUTat10.1Imported.

    Entry informationi

    Entry nameiD6XJX8_TRYB2
    AccessioniPrimary (citable) accession number: D6XJX8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 28, 2011
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3