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Protein
Submitted name:

DNA ligase, putative

Gene

Tb927.7.600

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
DNA ligase, putativeImported (EC:6.5.1.1Imported)
Gene namesi
ORF Names:Tb927.7.600Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
ProteomesiUP000008524 Componenti: Chromosome 7

Subcellular locationi

GO - Cellular componenti

  1. kinetoplast Source: GeneDB
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliD6XJX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000258023.
InParanoidiD6XJX8.
KOiK10747.
OMAiLECCHGL.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR029319. DNA_ligase_OB.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF01068. DNA_ligase_A_M. 1 hit.
PF14743. DNA_ligase_OB_2. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6XJX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRISNLWRR PQLTTLPKDP SLFFGVGRPR TPEQVERYHA MKNTTIESAF
60 70 80 90 100
PHLAACWVGP SWGTVMLTPH HVAPTCVKSA VWRCSQCLQE FEMSIARFID
110 120 130 140 150
QHGTCPLCGK EQRRISSTRN EGPERINGKM SEGDNTDVGI TTSPTDATNE
160 170 180 190 200
EDLELEDVNS LRAPRMTHTN YKSVLHSNPE WEGRNILPML AQRWELVAEE
210 220 230 240 250
LLHPADTEEQ ESLLVSPKID GIRCLIGYNK SQKKLQFFSR SGILLECCHG
260 270 280 290 300
LVPHAMPLFK ADPSLLLDGE LFAPHCGFER LSGLVRRLEK FTTQTTRRKQ
310 320 330 340 350
AKLLEYFAFD IMASDQLSSP DAPFSERYRL LKELIPHSGA DRVFDTMKPN
360 370 380 390 400
GRRNHQLEKE ELSSRKKIPK LYHVPATLVS PDEVESVLEK ACSQGYEGVI
410 420 430 440 450
IRRPKFPYEH GKRSLGLLKY KYMHDAEYRI VDFLPGNGKF EGGLGAFVCE
460 470 480 490 500
TSTGIRFNAT PKTTTKRRLE LWAERDRLLG KYLTVQYQEL SSQDVPRFPI
510
AKCVRGESEK DWL
Length:513
Mass (Da):58,617
Last modified:June 28, 2011 - v1
Checksum:i229080A827159E2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159437 Genomic DNA. Translation: AAX70312.1.
CP000070 Genomic DNA. Translation: AAZ12125.1.
RefSeqiXP_845684.1. XM_840591.1.

Genome annotation databases

GeneIDi3658273.
KEGGitbr:Tb927.7.600.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159437 Genomic DNA. Translation: AAX70312.1.
CP000070 Genomic DNA. Translation: AAZ12125.1.
RefSeqiXP_845684.1. XM_840591.1.

3D structure databases

ProteinModelPortaliD6XJX8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3658273.
KEGGitbr:Tb927.7.600.

Phylogenomic databases

HOGENOMiHOG000258023.
InParanoidiD6XJX8.
KOiK10747.
OMAiLECCHGL.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR029319. DNA_ligase_OB.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF01068. DNA_ligase_A_M. 1 hit.
PF14743. DNA_ligase_OB_2. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 927/4 GUTat10.1Imported.
  2. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.

Entry informationi

Entry nameiD6XJX8_TRYB2
AccessioniPrimary (citable) accession number: D6XJX8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 29, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.