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D6XJX8 (D6XJX8_TRYB2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=6.5.1.1 EMBL AAZ12125.1
Gene names
ORF Names:Tb927.7.600 EMBL AAZ12125.1
OrganismTrypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]
Taxonomic identifier999953 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Keywords
   Molecular functionLigase EMBL AAZ12125.1
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA ligation involved in DNA repair

Inferred from electronic annotation. Source: InterPro

DNA recombination

Inferred from electronic annotation. Source: InterPro

   Cellular_componentkinetoplast

Inferred from direct assay PubMed 15821136. Source: GeneDB_Tbrucei

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

DNA ligase (ATP) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D6XJX8 [UniParc].

Last modified June 28, 2011. Version 1.
Checksum: 229080A827159E2C

FASTA51358,617
        10         20         30         40         50         60 
MWRISNLWRR PQLTTLPKDP SLFFGVGRPR TPEQVERYHA MKNTTIESAF PHLAACWVGP 

        70         80         90        100        110        120 
SWGTVMLTPH HVAPTCVKSA VWRCSQCLQE FEMSIARFID QHGTCPLCGK EQRRISSTRN 

       130        140        150        160        170        180 
EGPERINGKM SEGDNTDVGI TTSPTDATNE EDLELEDVNS LRAPRMTHTN YKSVLHSNPE 

       190        200        210        220        230        240 
WEGRNILPML AQRWELVAEE LLHPADTEEQ ESLLVSPKID GIRCLIGYNK SQKKLQFFSR 

       250        260        270        280        290        300 
SGILLECCHG LVPHAMPLFK ADPSLLLDGE LFAPHCGFER LSGLVRRLEK FTTQTTRRKQ 

       310        320        330        340        350        360 
AKLLEYFAFD IMASDQLSSP DAPFSERYRL LKELIPHSGA DRVFDTMKPN GRRNHQLEKE 

       370        380        390        400        410        420 
ELSSRKKIPK LYHVPATLVS PDEVESVLEK ACSQGYEGVI IRRPKFPYEH GKRSLGLLKY 

       430        440        450        460        470        480 
KYMHDAEYRI VDFLPGNGKF EGGLGAFVCE TSTGIRFNAT PKTTTKRRLE LWAERDRLLG 

       490        500        510 
KYLTVQYQEL SSQDVPRFPI AKCVRGESEK DWL 

« Hide

References

« Hide 'large scale' references
[1]"Comparative genomics of trypanosomatid parasitic protozoa."
El-Sayed N.M.A., Myler P.J., Blandin G., Berriman M., Crabtree J., Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.-N., Wortman J.R., Alsmark U.C.M., Angiuoli S. expand/collapse author list , Anupama A., Badger J., Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.
Science 309:404-409(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[2]"The genome of the African trypanosome Trypanosoma brucei."
Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. expand/collapse author list , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[3]"Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. expand/collapse author list , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[4]Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. expand/collapse author list , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GUTat10.1 EMBL AAX70312.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC159437 Genomic DNA. Translation: AAX70312.1.
CP000070 Genomic DNA. Translation: AAZ12125.1.
RefSeqXP_845684.1. XM_840591.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3658273.
KEGGtbr:Tb927.7.600.

Phylogenomic databases

HOGENOMHOG000258023.
KOK01971.
OMALECCHGL.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
InterProIPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
PROSITEPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD6XJX8_TRYB2
AccessionPrimary (citable) accession number: D6XJX8
Entry history
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 16, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)