D6XJX8 (D6XJX8_TRYB2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA ligase, putative EMBL AAZ12125.1
EC=6.5.1.1 EMBL AAZ12125.1

Gene names

ORF Names:

Tb927.7.600 EMBL AAZ12125.1

Organism

Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]

Taxonomic identifier

999953 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Trypanozoon › Trypanosoma brucei › Trypanosoma brucei brucei

Protein attributes

Sequence length	513 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL AAZ12125.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D6XJX8 [UniParc]. Last modified June 28, 2011. Version 1. Checksum: 229080A827159E2C	FASTA	513	58,617
	10 20 30 40 50 60 MWRISNLWRR PQLTTLPKDP SLFFGVGRPR TPEQVERYHA MKNTTIESAF PHLAACWVGP 70 80 90 100 110 120 SWGTVMLTPH HVAPTCVKSA VWRCSQCLQE FEMSIARFID QHGTCPLCGK EQRRISSTRN 130 140 150 160 170 180 EGPERINGKM SEGDNTDVGI TTSPTDATNE EDLELEDVNS LRAPRMTHTN YKSVLHSNPE 190 200 210 220 230 240 WEGRNILPML AQRWELVAEE LLHPADTEEQ ESLLVSPKID GIRCLIGYNK SQKKLQFFSR 250 260 270 280 290 300 SGILLECCHG LVPHAMPLFK ADPSLLLDGE LFAPHCGFER LSGLVRRLEK FTTQTTRRKQ 310 320 330 340 350 360 AKLLEYFAFD IMASDQLSSP DAPFSERYRL LKELIPHSGA DRVFDTMKPN GRRNHQLEKE 370 380 390 400 410 420 ELSSRKKIPK LYHVPATLVS PDEVESVLEK ACSQGYEGVI IRRPKFPYEH GKRSLGLLKY 430 440 450 460 470 480 KYMHDAEYRI VDFLPGNGKF EGGLGAFVCE TSTGIRFNAT PKTTTKRRLE LWAERDRLLG 490 500 510 KYLTVQYQEL SSQDVPRFPI AKCVRGESEK DWL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomics of trypanosomatid parasitic protozoa." El-Sayed N.M.A., Myler P.J., Blandin G., Berriman M., Crabtree J., Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.-N., Wortman J.R., Alsmark U.C.M., Angiuoli S. , Anupama A., Badger J., Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N. Science 309:404-409(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[2]	"The genome of the African trypanosome Trypanosoma brucei." Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A. Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[3]	"Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8." Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 927/4 GUTat10.1 EMBL AAZ12125.1.
[4]	Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: GUTat10.1 EMBL AAX70312.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC159437 Genomic DNA. Translation: AAX70312.1. CP000070 Genomic DNA. Translation: AAZ12125.1.
RefSeq	XP_845684.1. XM_840591.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3658273.
KEGG	tbr:Tb927.7.600.
Phylogenomic databases
HOGENOM	HOG000258023.
KO	K01971.
OMA	LECCHGL.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF01068. DNA_ligase_A_M. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
PROSITE	PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D6XJX8_TRYB2

Accession

Primary (citable) accession number: D6XJX8

Entry history

Integrated into UniProtKB/TrEMBL:	June 28, 2011
Last sequence update:	June 28, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)