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Protein
Submitted name:

Carbonyl reductase

Gene

a1-R

Organism
Sphingomonas sp. A1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei92NADP; via carbonyl oxygenCombined sources1
Binding sitei164NADPCombined sources1
Binding sitei168NADPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 19NADPCombined sources4
Nucleotide bindingi39 – 40NADPCombined sources2
Nucleotide bindingi65 – 66NADPCombined sources2
Nucleotide bindingi194 – 202NADPCombined sources9

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Carbonyl reductaseImported
Gene namesi
Name:a1-RImported
OrganismiSphingomonas sp. A1Imported
Taxonomic identifieri90322 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3AFMX-ray1.65A/B1-258[»]
3AFNX-ray1.63A/B/C/D1-258[»]
4W7HX-ray3.11A/B1-258[»]
ProteinModelPortaliD6RU56.
SMRiD6RU56.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiD6RU56.

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RU56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPDLKGKRV LITGSSQGIG LATARLFARA GAKVGLHGRK APANIDETIA
60 70 80 90 100
SMRADGGDAA FFAADLATSE ACQQLVDEFV AKFGGIDVLI NNAGGLVGRK
110 120 130 140 150
PLPEIDDTFY DAVMDANIRS VVMTTKFALP HLAAAAKASG QTSAVISTGS
160 170 180 190 200
IAGHTGGGPG AGLYGAAKAF LHNVHKNWVD FHTKDGVRFN IVSPGTVDTA
210 220 230 240 250
FHADKTQDVR DRISNGIPMG RFGTAEEMAP AFLFFASHLA SGYITGQVLD

INGGQYKH
Length:258
Mass (Da):26,948
Last modified:August 10, 2010 - v1
Checksum:i1B477FAD2E83FA8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB537450 Genomic DNA. Translation: BAJ09322.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB537450 Genomic DNA. Translation: BAJ09322.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3AFMX-ray1.65A/B1-258[»]
3AFNX-ray1.63A/B/C/D1-258[»]
4W7HX-ray3.11A/B1-258[»]
ProteinModelPortaliD6RU56.
SMRiD6RU56.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiD6RU56.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD6RU56_9SPHN
AccessioniPrimary (citable) accession number: D6RU56
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: November 2, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.