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Protein
Submitted name:

Carbonyl reductase

Gene

a1-R

Organism
Sphingomonas sp. A1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei92 – 921NADP; via carbonyl oxygenCombined sources
Binding sitei164 – 1641NADPCombined sources
Binding sitei168 – 1681NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 194NADPCombined sources
Nucleotide bindingi39 – 402NADPCombined sources
Nucleotide bindingi65 – 662NADPCombined sources
Nucleotide bindingi194 – 2029NADPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Carbonyl reductaseImported
Gene namesi
Name:a1-RImported
OrganismiSphingomonas sp. A1Imported
Taxonomic identifieri90322 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3AFMX-ray1.65A/B1-258[»]
3AFNX-ray1.63A/B/C/D1-258[»]
4W7HX-ray3.11A/B1-258[»]
ProteinModelPortaliD6RU56.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiD6RU56.

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RU56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPDLKGKRV LITGSSQGIG LATARLFARA GAKVGLHGRK APANIDETIA
60 70 80 90 100
SMRADGGDAA FFAADLATSE ACQQLVDEFV AKFGGIDVLI NNAGGLVGRK
110 120 130 140 150
PLPEIDDTFY DAVMDANIRS VVMTTKFALP HLAAAAKASG QTSAVISTGS
160 170 180 190 200
IAGHTGGGPG AGLYGAAKAF LHNVHKNWVD FHTKDGVRFN IVSPGTVDTA
210 220 230 240 250
FHADKTQDVR DRISNGIPMG RFGTAEEMAP AFLFFASHLA SGYITGQVLD

INGGQYKH
Length:258
Mass (Da):26,948
Last modified:August 10, 2010 - v1
Checksum:i1B477FAD2E83FA8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB537450 Genomic DNA. Translation: BAJ09322.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB537450 Genomic DNA. Translation: BAJ09322.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3AFMX-ray1.65A/B1-258[»]
3AFNX-ray1.63A/B/C/D1-258[»]
4W7HX-ray3.11A/B1-258[»]
ProteinModelPortaliD6RU56.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiD6RU56.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD6RU56_9SPHN
AccessioniPrimary (citable) accession number: D6RU56
Entry historyi
Integrated into UniProtKB/TrEMBL: August 10, 2010
Last sequence update: August 10, 2010
Last modified: June 8, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.