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Protein
Submitted name:

Rho guanine nucleotide exchange factor 37

Gene

ARHGEF37

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 37Imported
Gene namesi
Name:ARHGEF37Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:34430. ARHGEF37.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183111.

PTM / Processingi

Proteomic databases

MaxQBiD6RJH4.
PaxDbiD6RJH4.
PeptideAtlasiD6RJH4.

Expressioni

Gene expression databases

BgeeiENSG00000183111.
ExpressionAtlasiD6RJH4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000328083.

Structurei

3D structure databases

ProteinModelPortaliD6RJH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 103DH (DBL-homology)InterPro annotationAdd BLAST74

Phylogenomic databases

eggNOGiKOG3519. Eukaryota.
ENOG410YAZC. LUCA.
GeneTreeiENSGT00530000063159.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
[Graphical view]
PfamiPF00621. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RJH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKHGADEPS SRSGSPDREG RASEDRSLLH QRLAVRELID TEVSYLHMLQ
60 70 80 90 100
LCASDIRSRL QQLPQGDLDV LFSNIDDIIK VNSRFLHDLQ ETASKEEEQV

QLV
Length:103
Mass (Da):11,684
Last modified:July 13, 2010 - v1
Checksum:i562DB3784A1AB334
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei103Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021078 Genomic DNA. No translation available.
AC022100 Genomic DNA. No translation available.
AC116360 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000505810; ENSP00000425621; ENSG00000183111.
UCSCiuc063iow.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021078 Genomic DNA. No translation available.
AC022100 Genomic DNA. No translation available.
AC116360 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RJH4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000328083.

Proteomic databases

MaxQBiD6RJH4.
PaxDbiD6RJH4.
PeptideAtlasiD6RJH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000505810; ENSP00000425621; ENSG00000183111.
UCSCiuc063iow.1. human.

Organism-specific databases

HGNCiHGNC:34430. ARHGEF37.
OpenTargetsiENSG00000183111.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3519. Eukaryota.
ENOG410YAZC. LUCA.
GeneTreeiENSGT00530000063159.

Miscellaneous databases

ChiTaRSiARHGEF37. human.

Gene expression databases

BgeeiENSG00000183111.
ExpressionAtlasiD6RJH4. baseline and differential.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
[Graphical view]
PfamiPF00621. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD6RJH4_HUMAN
AccessioniPrimary (citable) accession number: D6RJH4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 30, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.