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D6RJH4

- D6RJH4_HUMAN

UniProt

D6RJH4 - D6RJH4_HUMAN

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Protein
Submitted name: Rho guanine nucleotide exchange factor 37
Gene
ARHGEF37
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Rho guanine nucleotide exchange factor 37Imported
    Gene namesi
    Name:ARHGEF37Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:34430. ARHGEF37.

    Expressioni

    Gene expression databases

    ArrayExpressiD6RJH4.
    BgeeiD6RJH4.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RJH4.
    SMRiD6RJH4. Positions 29-98.

    Family & Domainsi

    Family and domain databases

    Gene3Di1.20.900.10. 1 hit.
    InterProiIPR000219. DH-domain.
    [Graphical view]
    PfamiPF00621. RhoGEF. 1 hit.
    [Graphical view]
    SUPFAMiSSF48065. SSF48065. 1 hit.
    PROSITEiPS50010. DH_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D6RJH4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKHGADEPS SRSGSPDREG RASEDRSLLH QRLAVRELID TEVSYLHMLQ    50
    LCASDIRSRL QQLPQGDLDV LFSNIDDIIK VNSRFLHDLQ ETASKEEEQV 100
    QLV 103
    Length:103
    Mass (Da):11,684
    Last modified:July 13, 2010 - v1
    Checksum:i562DB3784A1AB334
    GO

    Non-terminal residue

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei103 – 1031Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC021078 Genomic DNA. No translation available.
    AC022100 Genomic DNA. No translation available.
    AC116360 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000505810; ENSP00000425621; ENSG00000183111.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC021078 Genomic DNA. No translation available.
    AC022100 Genomic DNA. No translation available.
    AC116360 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RJH4.
    SMRi D6RJH4. Positions 29-98.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000505810 ; ENSP00000425621 ; ENSG00000183111 .

    Organism-specific databases

    HGNCi HGNC:34430. ARHGEF37.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35495051.

    Gene expression databases

    ArrayExpressi D6RJH4.
    Bgeei D6RJH4.

    Family and domain databases

    Gene3Di 1.20.900.10. 1 hit.
    InterProi IPR000219. DH-domain.
    [Graphical view ]
    Pfami PF00621. RhoGEF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48065. SSF48065. 1 hit.
    PROSITEi PS50010. DH_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RJH4_HUMAN
    AccessioniPrimary (citable) accession number: D6RJH4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: July 9, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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