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Protein
Submitted name:

Rho guanine nucleotide exchange factor 37

Gene

ARHGEF37

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 37Imported
Gene namesi
Name:ARHGEF37Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000183111.11
HGNCiHGNC:34430 ARHGEF37

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183111

PTM / Processingi

Proteomic databases

MaxQBiD6RJH4
PeptideAtlasiD6RJH4

Expressioni

Gene expression databases

BgeeiENSG00000183111
ExpressionAtlasiD6RJH4 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD6RJH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 103DHInterPro annotationAdd BLAST74

Phylogenomic databases

eggNOGiKOG3519 Eukaryota
ENOG410YAZC LUCA
GeneTreeiENSGT00530000063159

Family and domain databases

Gene3Di1.20.900.10, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
PfamiView protein in Pfam
PF00621 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit

Sequencei

Sequence statusi: Fragment.

D6RJH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKHGADEPS SRSGSPDREG RASEDRSLLH QRLAVRELID TEVSYLHMLQ
60 70 80 90 100
LCASDIRSRL QQLPQGDLDV LFSNIDDIIK VNSRFLHDLQ ETASKEEEQV

QLV
Length:103
Mass (Da):11,684
Last modified:July 13, 2010 - v1
Checksum:i562DB3784A1AB334
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei103Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021078 Genomic DNA No translation available.
AC022100 Genomic DNA No translation available.
AC116360 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000505810; ENSP00000425621; ENSG00000183111
UCSCiuc063iow.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RJH4_HUMAN
AccessioniPrimary (citable) accession number: D6RJH4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health