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Protein
Submitted name:

Syntaxin-4

Gene

Stx4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. SNAP receptor activity Source: GO_Central
  2. sphingomyelin phosphodiesterase activator activity Source: MGI

GO - Biological processi

  1. intracellular protein transport Source: GO_Central
  2. long-term synaptic potentiation Source: MGI
  3. organelle fusion Source: MGI
  4. positive regulation of catalytic activity Source: MGI
  5. positive regulation of cell adhesion Source: MGI
  6. positive regulation of cell migration Source: MGI
  7. positive regulation of cell proliferation Source: MGI
  8. positive regulation of chemotaxis Source: MGI
  9. positive regulation of eosinophil degranulation Source: MGI
  10. positive regulation of establishment of protein localization to plasma membrane Source: MGI
  11. positive regulation of immunoglobulin secretion Source: MGI
  12. positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
  13. positive regulation of protein localization to cell surface Source: MGI
  14. positive regulation of protein localization to plasma membrane Source: MGI
  15. regulation of exocytosis Source: MGI
  16. regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: MGI
  17. response to hydroperoxide Source: MGI
  18. synaptic vesicle exocytosis Source: MGI
  19. synaptic vesicle fusion to presynaptic membrane Source: GO_Central
  20. vesicle docking Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Syntaxin-4Imported
Gene namesi
Name:Stx4aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:893577. Stx4a.

Subcellular locationi

GO - Cellular componenti

  1. basolateral plasma membrane Source: MGI
  2. cell surface Source: MGI
  3. cytoplasm Source: MGI
  4. dendritic spine Source: MGI
  5. endosome Source: MGI
  6. extracellular space Source: MGI
  7. extracellular vesicular exosome Source: MGI
  8. integral component of membrane Source: GO_Central
  9. intracellular Source: MGI
  10. lamellipodium Source: MGI
  11. membrane Source: MGI
  12. plasma membrane Source: MGI
  13. SNARE complex Source: MGI
  14. somatodendritic compartment Source: MGI
  15. specific granule Source: MGI
  16. synapse Source: MGI
  17. synaptic vesicle Source: GO_Central
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD6RJ29.
ExpressionAtlasiD6RJ29. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119200.

Sequencei

Sequence statusi: Complete.

D6RJ29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MRDRTHELRQ GDNISDDEDE VRVALVVHSG AARLGSPDDE FFQKPSW
Length:47
Mass (Da):5,383
Last modified:July 13, 2010 - v1
Checksum:i93F28BD938DE5D25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC149222 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000156537; ENSMUSP00000118034; ENSMUSG00000030805.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC149222 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000156537; ENSMUSP00000118034; ENSMUSG00000030805.

Organism-specific databases

MGIiMGI:893577. Stx4a.

Phylogenomic databases

GeneTreeiENSGT00760000119200.

Miscellaneous databases

NextBioi35552713.
SOURCEiSearch...

Gene expression databases

BgeeiD6RJ29.
ExpressionAtlasiD6RJ29. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD6RJ29_MOUSE
AccessioniPrimary (citable) accession number: D6RJ29
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 4, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.