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Protein
Submitted name:

DNA polymerase subunit gamma-1

Gene

Polg

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. DNA binding Source: InterPro
  3. DNA-directed DNA polymerase activity Source: MGI
  4. exonuclease activity Source: MGI
  5. protease binding Source: MGI

GO - Biological processi

  1. aging Source: MGI
  2. DNA biosynthetic process Source: MGI
  3. mitochondrial DNA replication Source: MGI
  4. nucleic acid phosphodiester bond hydrolysis Source: GOC
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase subunit gamma-1Imported
Gene namesi
Name:PolgImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1196389. Polg.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: MGI
  2. gamma DNA polymerase complex Source: InterPro
  3. mitochondrial inner membrane Source: MGI
  4. mitochondrial nucleoid Source: MGI
  5. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD6RIP1.

Expressioni

Gene expression databases

BgeeiD6RIP1.
ExpressionAtlasiD6RIP1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RIP1.
SMRiD6RIP1. Positions 53-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000000453.
HOGENOMiHOG000207434.

Family and domain databases

InterProiIPR002297. DNA-dir_DNA_pol_A_mt.
IPR012337. RNaseH-like_dom.
[Graphical view]
PANTHERiPTHR10267. PTHR10267. 1 hit.
PRINTSiPR00867. DNAPOLG.
SUPFAMiSSF53098. SSF53098. 2 hits.

Sequencei

Sequence statusi: Complete.

D6RIP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRLLWKKVA GAKVASGPVP ATARWVSSSV LDPVPSDGRP PSQMPSSENG
60 70 80 90 100
QLRLNPLLIQ MLSRGLHEQI FGCGGEMPDE AAVQRSVEHL QKHGLWGQPA
110 120 130 140 150
TPLPDVELRL PRLFGGNLDQ HFRLLAQKQS LPYLEAAASL LEAQLPPEPK
160 170 180 190 200
SWAWAEGWTR YGPEGEAEPV AIPEERALVF DVEVCLAEGT CPTLAVAISP
210 220 230 240 250
SAWYSWCSRR LVEERYSWTS QLSPADLIPL GGSTSASSST KQDGQEQLVV
260 270 280 290 300
GHNVSFDRAH IREQYLIQDS RMRFLDTMSM HMAISGLSSF QRSLWMGAKQ
310 320 330 340 350
GKHKTQQSTK RGQKSPRKAN GPAISSWDWM DISSANNLAD VHNLYVGGPP
360 370 380 390 400
LEKEPRELFV KGSMRDIREN FQDLMQYCAR DVWATFEVFQ QQLPLFLERC
410 420 430 440 450
PHPVTLAGML EMGVSYLPVN QNWERYLTEA QNTYEELQRE MKKSLMDLAN
460 470 480 490
DACQLLSGER YKEDPWLWDL EWDLQEFKQK KAKKILARPA RRRSFSEV
Length:498
Mass (Da):56,301
Last modified:July 13, 2010 - v1
Checksum:i7EC4BFC233EB80CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110909 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000149444; ENSMUSP00000119616; ENSMUSG00000039176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110909 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RIP1.
SMRiD6RIP1. Positions 53-490.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD6RIP1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000149444; ENSMUSP00000119616; ENSMUSG00000039176.

Organism-specific databases

MGIiMGI:1196389. Polg.

Phylogenomic databases

GeneTreeiENSGT00390000000453.
HOGENOMiHOG000207434.

Miscellaneous databases

NextBioi35552680.
SOURCEiSearch...

Gene expression databases

BgeeiD6RIP1.
ExpressionAtlasiD6RIP1. baseline and differential.

Family and domain databases

InterProiIPR002297. DNA-dir_DNA_pol_A_mt.
IPR012337. RNaseH-like_dom.
[Graphical view]
PANTHERiPTHR10267. PTHR10267. 1 hit.
PRINTSiPR00867. DNAPOLG.
SUPFAMiSSF53098. SSF53098. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD6RIP1_MOUSE
AccessioniPrimary (citable) accession number: D6RIP1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: February 4, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.