ID   D6RHX7_HUMAN            Unreviewed;       331 AA.
AC   D6RHX7;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Mitogen-activated protein kinase binding protein 1 {ECO:0000313|Ensembl:ENSP00000427582.1};
GN   Name=MAPKBP1 {ECO:0000313|Ensembl:ENSP00000427582.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000427582.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000427582.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S.,
RA   Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R.,
RA   Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0007829|PubMed:22814378}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN   [3] {ECO:0000313|Ensembl:ENSP00000427582.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC020659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC073657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; D6RHX7; -.
DR   SMR; D6RHX7; -.
DR   MassIVE; D6RHX7; -.
DR   MaxQB; D6RHX7; -.
DR   PeptideAtlas; D6RHX7; -.
DR   ProteomicsDB; 14892; -.
DR   Ensembl; ENST00000512970.5; ENSP00000427582.1; ENSG00000137802.14.
DR   UCSC; uc059iab.1; human.
DR   HGNC; HGNC:29536; MAPKBP1.
DR   VEuPathDB; HostDB:ENSG00000137802; -.
DR   GeneTree; ENSGT00940000160664; -.
DR   HOGENOM; CLU_800055_0_0_1; -.
DR   ChiTaRS; MAPKBP1; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000137802; Expressed in right hemisphere of cerebellum and 169 other cell types or tissues.
DR   ExpressionAtlas; D6RHX7; baseline and differential.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR44813; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR   PANTHER; PTHR44813:SF1; MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:D6RHX7,
KW   ECO:0007829|MaxQB:D6RHX7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
SQ   SEQUENCE   331 AA;  36273 MW;  4CE484209C107D02 CRC64;
     MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS GGRGLACDPR
     SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP DGKYLVTGES GHMPAVRVWD
     VAEHSQVAEL QEHKYGVACV AFSPSAKYIV SVGYQHDMIV NVWAWKKNIV VASNKVSSRV
     TAVSFSEDCS YFVTAGNRHI KFWYLDDSKT SKVNATVPLL GRSGLLGELR NNLFTDVACG
     RGKKADSTFC ITSSGLLCEF SDRRLLDKWV ELRTTVAHCI SVSQDYIFCG CADGTVRLFN
     PSNLHFLSTL PRPHALGTDI ASVTEARSTP R
//