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Protein
Submitted name:

Mitogen-activated protein kinase-binding protein 1

Gene

MAPKBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiD6RHX7.

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase-binding protein 1Imported
Gene namesi
Name:MAPKBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:29536. MAPKBP1.

Expressioni

Gene expression databases

BgeeiD6RHX7.
ExpressionAtlasiD6RHX7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000393099.

Structurei

3D structure databases

ProteinModelPortaliD6RHX7.
SMRiD6RHX7. Positions 12-212.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00770000120572.
HOGENOMiHOG000169121.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 4 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6RHX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS
60 70 80 90 100
GGRGLACDPR SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP
110 120 130 140 150
DGKYLVTGES GHMPAVRVWD VAEHSQVAEL QEHKYGVACV AFSPSAKYIV
160 170 180 190 200
SVGYQHDMIV NVWAWKKNIV VASNKVSSRV TAVSFSEDCS YFVTAGNRHI
210 220 230 240 250
KFWYLDDSKT SKVNATVPLL GRSGLLGELR NNLFTDVACG RGKKADSTFC
260 270 280 290 300
ITSSGLLCEF SDRRLLDKWV ELRTTVAHCI SVSQDYIFCG CADGTVRLFN
310 320 330
PSNLHFLSTL PRPHALGTDI ASVTEARSTP R
Length:331
Mass (Da):36,273
Last modified:July 13, 2010 - v1
Checksum:i4CE484209C107D02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020659 Genomic DNA. No translation available.
AC073657 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000512970; ENSP00000427582; ENSG00000137802.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020659 Genomic DNA. No translation available.
AC073657 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RHX7.
SMRiD6RHX7. Positions 12-212.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000393099.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000512970; ENSP00000427582; ENSG00000137802.

Organism-specific databases

HGNCiHGNC:29536. MAPKBP1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00770000120572.
HOGENOMiHOG000169121.

Enzyme and pathway databases

SignaLinkiD6RHX7.

Miscellaneous databases

ChiTaRSiMAPKBP1. human.
NextBioi35494797.

Gene expression databases

BgeeiD6RHX7.
ExpressionAtlasiD6RHX7. baseline and differential.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 4 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiPS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiD6RHX7_HUMAN
AccessioniPrimary (citable) accession number: D6RHX7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 24, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.