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Protein
Submitted name:

Interferon regulatory factor 1

Gene

Irf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 1Imported
Gene namesi
Name:Irf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:96590. Irf1.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000018899.
ExpressionAtlasiD6RH71. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RH71.
SMRiD6RH71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 51IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd BLAST47

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119093.
HOGENOMiHOG000185992.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR031215. IRF1.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PTHR11949:SF37. PTHR11949:SF37. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS51507. IRF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RH71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPITRMRMRP WLEMQINSNQ IPGLIWINKA DTKQEKKSQI PRHGRQTSVV

P
Length:51
Mass (Da):6,041
Last modified:July 13, 2010 - v1
Checksum:i81CC6E29DCE8D3BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596182 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000142221; ENSMUSP00000118795; ENSMUSG00000018899.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596182 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RH71.
SMRiD6RH71.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000142221; ENSMUSP00000118795; ENSMUSG00000018899.

Organism-specific databases

MGIiMGI:96590. Irf1.

Phylogenomic databases

GeneTreeiENSGT00760000119093.
HOGENOMiHOG000185992.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018899.
ExpressionAtlasiD6RH71. baseline and differential.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR031215. IRF1.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PTHR11949:SF37. PTHR11949:SF37. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS51507. IRF_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD6RH71_MOUSE
AccessioniPrimary (citable) accession number: D6RH71
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 15, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.