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Protein
Submitted name:

Interferon regulatory factor 1

Gene

Irf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 1Imported
Gene namesi
Name:Irf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:96590 Irf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000018899
ExpressionAtlasiD6RH71 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RH71
SMRiD6RH71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 51IRF tryptophan pentad repeatInterPro annotationAdd BLAST47

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119093
HOGENOMiHOG000185992

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR031215 IRF1
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PTHR11949:SF3 PTHR11949:SF3, 1 hit
PfamiView protein in Pfam
PF00605 IRF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51507 IRF_2, 1 hit

Sequencei

Sequence statusi: Complete.

D6RH71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPITRMRMRP WLEMQINSNQ IPGLIWINKA DTKQEKKSQI PRHGRQTSVV

P
Length:51
Mass (Da):6,041
Last modified:July 13, 2010 - v1
Checksum:i81CC6E29DCE8D3BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596182 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000142221; ENSMUSP00000118795; ENSMUSG00000018899

Similar proteinsi

Entry informationi

Entry nameiD6RH71_MOUSE
AccessioniPrimary (citable) accession number: D6RH71
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health