D6RH37 (D6RH37_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase N1 Ensembl ENSMUSP00000115054

Gene names

Name:

Pkn1 Ensembl ENSMUSP00000115054 MGI 108022

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000115054

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	796 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000115054

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 SAAS SAAS008973 Nucleotide-binding
Molecular function	Kinase SAAS SAAS008973 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	hyperosmotic response Inferred from direct assay PubMed 12783890. Source: MGI signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasmic membrane-bounded vesicle Inferred from direct assay PubMed 12783890. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein kinase activity Inferred from mutant phenotype PubMed 12783890. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D6RH37 [UniParc]. Last modified July 13, 2010. Version 1. Checksum: F772A7521BB81523	FASTA	796	87,195
	10 20 30 40 50 60 MACRPCRGAG RIWCCRSHKS EPRSWSLLEQ LGLAGADLAA PGVQQQLELE RERLKREIRK 70 80 90 100 110 120 ELKLKEGAEN LRRATTDLGR SLAPVELLLR GSARRLDLLH QQLQELHAHV VLPDPAAGSD 130 140 150 160 170 180 ATQSLAEGSP ICSSTNLSRV AGLEKQLAIE LKVKQGAENM IQTYSNGSSK DRKLLLTAQQ 190 200 210 220 230 240 MLQDSKTKID IIRMQLRRAL QALQAGELES QAAPDEAQGD PELGAVELRI EELRHHFRVE 250 260 270 280 290 300 HAVAEGAKNV LRLLSGAKAP DRKAVSEAQE KLTESNQKLG LLRESLERRL GELPADHPKG 310 320 330 340 350 360 RLLREELTAA SSSAFSAILP GPFPATHYST LSKPAPLTGT LEVRVVGCKN LPETIPWSPP 370 380 390 400 410 420 PSVGASGTPE SRTPFLSRPA RGLYSRSGSL SGRSSLRGEA ENATEVSTVL KLDNTVVGQT 430 440 450 460 470 480 AWKPCGPNAW DQSFTLELER ARELELAVFW RDQRGLCALK FLKLEDFLDN ERHEVQLDME 490 500 510 520 530 540 PQGCLVAEVT FRNPIIERIP RLQRQKKIFS KQQGKAFQRA RQMNIDVATW VRLLRRLIPS 550 560 570 580 590 600 AVATGTFSPN ASPGAEIRHT GDISMEKLNL GADSDSSSQK SPPGLPSTSC SLSSPTHEST 610 620 630 640 650 660 TSPELPSETQ ETPGPGLCSP LRKSPLTLED FKFLAVLGRG HFGKVLLSEF RSSGELFAIK 670 680 690 700 710 720 ALKKGDIVAR DEVESLMCEK RILAAVTRAG HPFLVNLFGC FQTPEHVCFV MEYSAGGDLM 730 740 750 760 770 780 LHIHSDVFSE PRAVFYSACV VLGLQFLHEH KIVYRDGLWG PDQHVLRNSG VPGAGSAHRH 790 ILHASSGLVG TGRAAL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000115054.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000115054.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC164432 Genomic DNA. No translation available.
IPI	IPI00856536.
3D structure databases
ProteinModelPortal	D6RH37.
SMR	D6RH37. Positions 25-110, 134-214, 598-781.
ModBase	Search...
Proteomic databases
PRIDE	D6RH37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000132945; ENSMUSP00000115054; ENSMUSG00000057672.
Organism-specific databases
MGI	MGI:108022. Pkn1.
Phylogenomic databases
GeneTree	ENSGT00700000104096.
HOGENOM	HOG000233032.
Gene expression databases
ArrayExpress	D6RH37.
Bgee	D6RH37.
Family and domain databases
Gene3D	1.10.287.160. 3 hits.
InterPro	IPR000008. C2_Ca-dep. IPR008973. C2_Ca/lipid-bd_dom_CaLB. IPR011072. HR1_rho-bd. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. [Graphical view]
Pfam	PF02185. HR1. 3 hits. PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00239. C2. 1 hit. SM00742. Hr1. 3 hits. [Graphical view]
SUPFAM	SSF49562. C2_CaLB. 1 hit. SSF56112. Kinase_like. 1 hit. SSF46585. PKN_effector. 3 hits.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PKN1. mouse.
NextBio	35552404.
SOURCE	Search...

Entry information

Entry name

D6RH37_MOUSE

Accession

Primary (citable) accession number: D6RH37

Entry history

Integrated into UniProtKB/TrEMBL:	July 13, 2010
Last sequence update:	July 13, 2010
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)