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Protein
Submitted name:

Nephronectin

Gene

NPNT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NephronectinImported
Gene namesi
Name:NPNTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:27405. NPNT.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiD6RH31.

Expressioni

Gene expression databases

BgeeiD6RH31.
ExpressionAtlasiD6RH31. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000389252.

Structurei

3D structure databases

ProteinModelPortaliD6RH31.
SMRiD6RH31. Positions 73-306, 465-609.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00770000120465.
HOGENOMiHOG000059638.
OMAiSLKKGHC.
PhylomeDBiD6RH31.

Family and domain databases

InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
IPR000998. MAM_dom.
[Graphical view]
PfamiPF07645. EGF_CA. 3 hits.
PF00629. MAM. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 3 hits.
SM00179. EGF_CA. 2 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 3 hits.
PS50060. MAM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RH31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLLALVLV SSLYLQAAAE FDGRWPRQIV SSIGLCRYGG RIDCCWGWAR
60 70 80 90 100
QSWGQCQPFY VLRQRIARIR CQLKAVCQPR CKHGECIGPN KCKCHPGYAG
110 120 130 140 150
KTCNQDEHIP APLDQGSEQP LFQPLDHQAT SLPSRDLNEC GLKPRPCKHR
160 170 180 190 200
CMNTYGSYKC YCLNGYMLMP DGSCSSALTC SMANCQYGCD VVKGQIRCQC
210 220 230 240 250
PSPGLQLAPD GRTCVDVDEC ATGRASCPRF RQCVNTFGSY ICKCHKGFDL
260 270 280 290 300
MYIGGKYQCH DIDECSLGQY QCSSFARCYN IRGSYKCKCK EGYQGDGLTC
310 320 330 340 350
VYIPKVMIEP SGPIHVPKGN GTILKGDTGN NNWIPDVGST WWPPKTPYIP
360 370 380 390 400
PIITNRPTSK PTTRPTPKPT PIPTPPPPPP LPTELRTPLP PTTPERPTTG
410 420 430 440 450
LTTIAPAAST PPGGITVDNR VQTDPQKPRG DVFIPRQPSN DLFEIFEIER
460 470 480 490 500
GVSADDEAKD DPGVLVHSCN FDHGLCGWIR EKDNDLHWEP IRDPAGGQYL
510 520 530 540 550
TVSAAKAPGG KAARLVLPLG RLMHSGDLCL SFRHKVTGLH SGTLQVFVRK
560 570 580 590 600
HGAHGAALWG RNGGHGWRQT QITLRGADIK SVVFKGEKRR GHTGEIGLDD

VSLKKGHCS
Length:609
Mass (Da):66,916
Last modified:July 13, 2010 - v1
Checksum:i0E54C2FDA351B1A7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei609 – 6091Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000503451; ENSP00000426146; ENSG00000168743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RH31.
SMRiD6RH31. Positions 73-306, 465-609.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000389252.

Proteomic databases

PRIDEiD6RH31.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000503451; ENSP00000426146; ENSG00000168743.

Organism-specific databases

HGNCiHGNC:27405. NPNT.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00770000120465.
HOGENOMiHOG000059638.
OMAiSLKKGHC.
PhylomeDBiD6RH31.

Miscellaneous databases

ChiTaRSiNPNT. human.
NextBioi35494702.

Gene expression databases

BgeeiD6RH31.
ExpressionAtlasiD6RH31. baseline and differential.

Family and domain databases

InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
IPR000998. MAM_dom.
[Graphical view]
PfamiPF07645. EGF_CA. 3 hits.
PF00629. MAM. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 3 hits.
SM00179. EGF_CA. 2 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 3 hits.
PS50060. MAM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RH31_HUMAN
AccessioniPrimary (citable) accession number: D6RH31
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 22, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.