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D6RH31

- D6RH31_HUMAN

UniProt

D6RH31 - D6RH31_HUMAN

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Protein
Submitted name:

Nephronectin

Gene

NPNT

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NephronectinImported
Gene namesi
Name:NPNTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:27405. NPNT.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiD6RH31.

Expressioni

Gene expression databases

BgeeiD6RH31.
ExpressionAtlasiD6RH31. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RH31.
SMRiD6RH31. Positions 73-306, 465-609.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00750000117321.
HOGENOMiHOG000059638.
OMAiWIREKDS.
PhylomeDBiD6RH31.

Family and domain databases

InterProiIPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
IPR000998. MAM_dom.
[Graphical view]
PfamiPF07645. EGF_CA. 3 hits.
PF00629. MAM. 1 hit.
[Graphical view]
SMARTiSM00181. EGF. 3 hits.
SM00179. EGF_CA. 2 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 3 hits.
PS50060. MAM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RH31-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDFLLALVLV SSLYLQAAAE FDGRWPRQIV SSIGLCRYGG RIDCCWGWAR
60 70 80 90 100
QSWGQCQPFY VLRQRIARIR CQLKAVCQPR CKHGECIGPN KCKCHPGYAG
110 120 130 140 150
KTCNQDEHIP APLDQGSEQP LFQPLDHQAT SLPSRDLNEC GLKPRPCKHR
160 170 180 190 200
CMNTYGSYKC YCLNGYMLMP DGSCSSALTC SMANCQYGCD VVKGQIRCQC
210 220 230 240 250
PSPGLQLAPD GRTCVDVDEC ATGRASCPRF RQCVNTFGSY ICKCHKGFDL
260 270 280 290 300
MYIGGKYQCH DIDECSLGQY QCSSFARCYN IRGSYKCKCK EGYQGDGLTC
310 320 330 340 350
VYIPKVMIEP SGPIHVPKGN GTILKGDTGN NNWIPDVGST WWPPKTPYIP
360 370 380 390 400
PIITNRPTSK PTTRPTPKPT PIPTPPPPPP LPTELRTPLP PTTPERPTTG
410 420 430 440 450
LTTIAPAAST PPGGITVDNR VQTDPQKPRG DVFIPRQPSN DLFEIFEIER
460 470 480 490 500
GVSADDEAKD DPGVLVHSCN FDHGLCGWIR EKDNDLHWEP IRDPAGGQYL
510 520 530 540 550
TVSAAKAPGG KAARLVLPLG RLMHSGDLCL SFRHKVTGLH SGTLQVFVRK
560 570 580 590 600
HGAHGAALWG RNGGHGWRQT QITLRGADIK SVVFKGEKRR GHTGEIGLDD

VSLKKGHCS
Length:609
Mass (Da):66,916
Last modified:July 13, 2010 - v1
Checksum:i0E54C2FDA351B1A7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei609 – 6091Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000503451; ENSP00000426146; ENSG00000168743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RH31.
SMRi D6RH31. Positions 73-306, 465-609.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D6RH31.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000503451 ; ENSP00000426146 ; ENSG00000168743 .

Organism-specific databases

HGNCi HGNC:27405. NPNT.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00750000117321.
HOGENOMi HOG000059638.
OMAi WIREKDS.
PhylomeDBi D6RH31.

Miscellaneous databases

ChiTaRSi NPNT. human.
NextBioi 35494702.

Gene expression databases

Bgeei D6RH31.
ExpressionAtlasi D6RH31. baseline and differential.

Family and domain databases

InterProi IPR013320. ConA-like_dom.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_N_dom.
IPR000998. MAM_dom.
[Graphical view ]
Pfami PF07645. EGF_CA. 3 hits.
PF00629. MAM. 1 hit.
[Graphical view ]
SMARTi SM00181. EGF. 3 hits.
SM00179. EGF_CA. 2 hits.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF57184. SSF57184. 1 hit.
PROSITEi PS00010. ASX_HYDROXYL. 3 hits.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 3 hits.
PS50060. MAM_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RH31_HUMAN
AccessioniPrimary (citable) accession number: D6RH31
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3