D6RH31 (D6RH31_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nephronectin Ensembl ENSP00000426146

Gene names

Name:

NPNT Ensembl ENSP00000426146

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000426146

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	609 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000426146

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS001881 RuleBase RU000459
PTM	Disulfide bond SAAS SAAS001881
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	609	1	Ensembl ENSP00000426146

Sequences

	Sequence		Length	Mass (Da)
	D6RH31 [UniParc]. Last modified July 13, 2010. Version 1. Checksum: 0E54C2FDA351B1A7	FASTA	609	66,916
	10 20 30 40 50 60 MDFLLALVLV SSLYLQAAAE FDGRWPRQIV SSIGLCRYGG RIDCCWGWAR QSWGQCQPFY 70 80 90 100 110 120 VLRQRIARIR CQLKAVCQPR CKHGECIGPN KCKCHPGYAG KTCNQDEHIP APLDQGSEQP 130 140 150 160 170 180 LFQPLDHQAT SLPSRDLNEC GLKPRPCKHR CMNTYGSYKC YCLNGYMLMP DGSCSSALTC 190 200 210 220 230 240 SMANCQYGCD VVKGQIRCQC PSPGLQLAPD GRTCVDVDEC ATGRASCPRF RQCVNTFGSY 250 260 270 280 290 300 ICKCHKGFDL MYIGGKYQCH DIDECSLGQY QCSSFARCYN IRGSYKCKCK EGYQGDGLTC 310 320 330 340 350 360 VYIPKVMIEP SGPIHVPKGN GTILKGDTGN NNWIPDVGST WWPPKTPYIP PIITNRPTSK 370 380 390 400 410 420 PTTRPTPKPT PIPTPPPPPP LPTELRTPLP PTTPERPTTG LTTIAPAAST PPGGITVDNR 430 440 450 460 470 480 VQTDPQKPRG DVFIPRQPSN DLFEIFEIER GVSADDEAKD DPGVLVHSCN FDHGLCGWIR 490 500 510 520 530 540 EKDNDLHWEP IRDPAGGQYL TVSAAKAPGG KAARLVLPLG RLMHSGDLCL SFRHKVTGLH 550 560 570 580 590 600 SGTLQVFVRK HGAHGAALWG RNGGHGWRQT QITLRGADIK SVVFKGEKRR GHTGEIGLDD VSLKKGHCS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC093782 Genomic DNA. No translation available. AC109361 Genomic DNA. No translation available.
IPI	IPI00964777.
3D structure databases
ProteinModelPortal	D6RH31.
SMR	D6RH31. Positions 73-306, 465-609.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000503451; ENSP00000426146; ENSG00000168743.
Organism-specific databases
HGNC	HGNC:27405. NPNT.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000059638.
OMA	SLKKGHC.
Gene expression databases
ArrayExpress	D6RH31.
Bgee	D6RH31.
Family and domain databases
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR018097. EGF_Ca-bd_CS. IPR000998. MAM_dom. [Graphical view]
Pfam	PF07645. EGF_CA. 3 hits. PF00629. MAM. 1 hit. [Graphical view]
SMART	SM00181. EGF. 3 hits. SM00179. EGF_CA. 2 hits. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS00010. ASX_HYDROXYL. 3 hits. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 3 hits. PS50026. EGF_3. 4 hits. PS01187. EGF_CA. 3 hits. PS50060. MAM_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NPNT. human.
NextBio	35494702.

Entry information

Entry name

D6RH31_HUMAN

Accession

Primary (citable) accession number: D6RH31

Entry history

Integrated into UniProtKB/TrEMBL:	July 13, 2010
Last sequence update:	July 13, 2010
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.