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D6RGW8

- D6RGW8_HUMAN

UniProt

D6RGW8 - D6RGW8_HUMAN

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Protein
Submitted name:

Bone morphogenetic protein receptor type-1B

Gene

BMPR1B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. receptor signaling protein serine/threonine kinase activity Source: InterPro
  3. transforming growth factor beta receptor activity, type I Source: Ensembl

GO - Biological processi

  1. BMP signaling pathway Source: Ensembl
  2. cartilage condensation Source: Ensembl
  3. chondrocyte differentiation Source: Ensembl
  4. dorsal/ventral pattern formation Source: Ensembl
  5. inflammatory response Source: Ensembl
  6. ovarian cumulus expansion Source: Ensembl
  7. positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
  8. retina development in camera-type eye Source: Ensembl
  9. retinal ganglion cell axon guidance Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Bone morphogenetic protein receptor type-1BImported
Gene namesi
Name:BMPR1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:1077. BMPR1B.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD6RGW8.
ExpressionAtlasiD6RGW8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RGW8.
SMRiD6RGW8. Positions 29-113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118876.

Family and domain databases

InterProiIPR000472. Activin_rcpt.
IPR000333. TGFB_receptor.
[Graphical view]
PANTHERiPTHR23255. PTHR23255. 1 hit.
PfamiPF01064. Activin_recp. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RGW8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD
60 70 80 90 100
GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN
110 120
ECNKDLHPTL PPLKNRDFVD GPIHH
Length:125
Mass (Da):13,900
Last modified:February 8, 2011 - v1
Checksum:i6DFA6903D499F5F6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei125 – 1251Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004061 Genomic DNA. No translation available.
AC092609 Genomic DNA. No translation available.
AC093634 Genomic DNA. No translation available.
AC105395 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000506363; ENSP00000421144; ENSG00000138696.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004061 Genomic DNA. No translation available.
AC092609 Genomic DNA. No translation available.
AC093634 Genomic DNA. No translation available.
AC105395 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RGW8.
SMRi D6RGW8. Positions 29-113.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000506363 ; ENSP00000421144 ; ENSG00000138696 .

Organism-specific databases

HGNCi HGNC:1077. BMPR1B.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118876.

Miscellaneous databases

ChiTaRSi BMPR1B. human.
NextBioi 35494651.

Gene expression databases

Bgeei D6RGW8.
ExpressionAtlasi D6RGW8. baseline and differential.

Family and domain databases

InterProi IPR000472. Activin_rcpt.
IPR000333. TGFB_receptor.
[Graphical view ]
PANTHERi PTHR23255. PTHR23255. 1 hit.
Pfami PF01064. Activin_recp. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RGW8_HUMAN
AccessioniPrimary (citable) accession number: D6RGW8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3