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D6RGW8

- D6RGW8_HUMAN

UniProt

D6RGW8 - D6RGW8_HUMAN

Protein
Submitted name:

Bone morphogenetic protein receptor type-1B

Gene

BMPR1B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. receptor signaling protein serine/threonine kinase activity Source: InterPro
    3. transforming growth factor beta receptor activity, type I Source: Ensembl

    GO - Biological processi

    1. BMP signaling pathway Source: Ensembl
    2. cartilage condensation Source: Ensembl
    3. chondrocyte differentiation Source: Ensembl
    4. dorsal/ventral pattern formation Source: Ensembl
    5. inflammatory response Source: Ensembl
    6. ovarian cumulus expansion Source: Ensembl
    7. positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
    8. retina development in camera-type eye Source: Ensembl
    9. retinal ganglion cell axon guidance Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bone morphogenetic protein receptor type-1BImported
    Gene namesi
    Name:BMPR1BImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:1077. BMPR1B.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiD6RGW8.
    BgeeiD6RGW8.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RGW8.
    SMRiD6RGW8. Positions 29-113.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR000472. Activin_rcpt.
    IPR000333. TGFB_receptor.
    [Graphical view]
    PANTHERiPTHR23255. PTHR23255. 1 hit.
    PfamiPF01064. Activin_recp. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D6RGW8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD    50
    GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN 100
    ECNKDLHPTL PPLKNRDFVD GPIHH 125
    Length:125
    Mass (Da):13,900
    Last modified:February 8, 2011 - v1
    Checksum:i6DFA6903D499F5F6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei125 – 1251Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004061 Genomic DNA. No translation available.
    AC092609 Genomic DNA. No translation available.
    AC093634 Genomic DNA. No translation available.
    AC105395 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000506363; ENSP00000421144; ENSG00000138696.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004061 Genomic DNA. No translation available.
    AC092609 Genomic DNA. No translation available.
    AC093634 Genomic DNA. No translation available.
    AC105395 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RGW8.
    SMRi D6RGW8. Positions 29-113.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000506363 ; ENSP00000421144 ; ENSG00000138696 .

    Organism-specific databases

    HGNCi HGNC:1077. BMPR1B.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi BMPR1B. human.
    NextBioi 35494651.

    Gene expression databases

    ArrayExpressi D6RGW8.
    Bgeei D6RGW8.

    Family and domain databases

    InterProi IPR000472. Activin_rcpt.
    IPR000333. TGFB_receptor.
    [Graphical view ]
    PANTHERi PTHR23255. PTHR23255. 1 hit.
    Pfami PF01064. Activin_recp. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RGW8_HUMAN
    AccessioniPrimary (citable) accession number: D6RGW8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3