Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Adenomatous polyposis coli protein

Gene

APC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adenomatous polyposis coli proteinImported
Gene namesi
Name:APCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000134982.16.
HGNCiHGNC:583. APC.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134982.

PTM / Processingi

Proteomic databases

MaxQBiD6RFL6.
PaxDbiD6RFL6.
PeptideAtlasiD6RFL6.
PRIDEiD6RFL6.

Expressioni

Gene expression databases

BgeeiENSG00000134982.
ExpressionAtlasiD6RFL6. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD6RFL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 55APC_N_CCInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili6 – 54Sequence analysisAdd BLAST49

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2122. Eukaryota.
ENOG410XR2V. LUCA.
GeneTreeiENSGT00530000063749.

Family and domain databases

InterProiView protein in InterPro
IPR026836. APC.
IPR026818. Apc_fam.
IPR032038. APC_N.
IPR036149. APC_N_sf.
PANTHERiPTHR12607. PTHR12607. 1 hit.
PTHR12607:SF11. PTHR12607:SF11. 1 hit.
PfamiView protein in Pfam
PF16689. APC_N_CC. 1 hit.
SUPFAMiSSF58050. SSF58050. 1 hit.

Sequencei

Sequence statusi: Fragment.

D6RFL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAASYDQLL KQVEALKMEN SNLRQELEDN SNHLTKLETE ASNMKEVLKQ
60 70 80 90 100
LQGSIEDEAM ASSGQIDLLE RLKELNLDSS NFPGVKLRSK MSLRSYGSRE
110
GSVSSRSGEC SPVPMGSF
Length:118
Mass (Da):13,028
Last modified:July 13, 2010 - v1
Checksum:iDCCFD3DB0A0E947E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei118Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008575 Genomic DNA. No translation available.
AC136500 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000509732; ENSP00000426541; ENSG00000134982.
UCSCiuc063gal.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RFL6_HUMAN
AccessioniPrimary (citable) accession number: D6RFL6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 25, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported