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Protein
Submitted name:

Nuclear factor NF-kappa-B p105 subunit

Gene

NFKB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor NF-kappa-B p105 subunitImported
Gene namesi
Name:NFKB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000109320.11
HGNCiHGNC:7794 NFKB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000109320

PTM / Processingi

Proteomic databases

MaxQBiD6RF93
PeptideAtlasiD6RF93
PRIDEiD6RF93

Expressioni

Gene expression databases

BgeeiENSG00000109320
ExpressionAtlasiD6RF93 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiD6RF93, 1 interactor
MINTiD6RF93

Structurei

3D structure databases

ProteinModelPortaliD6RF93
SMRiD6RF93
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 40RHDInterPro annotationAdd BLAST40

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00500000044765

Family and domain databases

CDDicd01177 IPT_NFkappaB, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR033926 IPT_NFkappaB
IPR030503 NF-kB_p105
IPR000451 NFkB/Dor
IPR008967 p53-like_TF_DNA-bd
IPR032397 RHD_dimer
IPR011539 RHD_DNA_bind_dom
IPR037059 RHD_DNA_bind_dom_sf
PANTHERiPTHR24169 PTHR24169, 1 hit
PTHR24169:SF9 PTHR24169:SF9, 1 hit
PfamiView protein in Pfam
PF16179 RHD_dimer, 1 hit
PF00554 RHD_DNA_bind, 1 hit
PRINTSiPR00057 NFKBTNSCPFCT
SMARTiView protein in SMART
SM00429 IPT, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS50254 REL_2, 1 hit

Sequencei

Sequence statusi: Fragment.

D6RF93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLSVVRLMF TAFLPDSTGS FTRRLEPVVS DAIYDSKAPN ASNLKIVRMD
60 70 80 90 100
RTAGCVTGGE EIYLLCDKVQ KDDIQIRFYE EEENGGVWEG FGDFSPTDVH
110 120 130 140 150
RQFAIVFKTP KYKDINITKP ASVFVQLRRK SDLETSEPKP FLYYPEIKDK
160 170 180 190
EEVQRKRQKL MPNFSDSFGG GSGAGAGGGG MFGSGGGGGG TGSTGP
Length:196
Mass (Da):21,399
Last modified:July 13, 2010 - v1
Checksum:i3BB8839A4CEDFFD5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei196Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF213884 Genomic DNA No translation available.
KF457798 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000508584; ENSP00000424815; ENSG00000109320
UCSCiuc062yor.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RF93_HUMAN
AccessioniPrimary (citable) accession number: D6RF93
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health