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Protein
Submitted name:

Cadherin-6

Gene

CDH6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-6Imported
Gene namesi
Name:CDH6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:1765. CDH6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiD6RF86.
ExpressionAtlasiD6RF86. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265071.

Structurei

3D structure databases

ProteinModelPortaliD6RF86.
SMRiD6RF86. Positions 1-534.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118954.
HOGENOMiHOG000231252.
OrthoDBiEOG7GBFW7.

Family and domain databases

Gene3Di2.60.40.60. 5 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6RF86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWNQFFLLEE YTGSDYQYVG KLHSDQDRGD GSLKYILSGD GAGDLFIINE
60 70 80 90 100
NTGDIQATKR LDREEKPVYI LRAQAINRRT GRPVEPESEF IIKIHDINDN
110 120 130 140 150
EPIFTKEVYT ATVPEMSDVG TFVVQVTATD ADDPTYGNSA KVVYSILQGQ
160 170 180 190 200
PYFSVESETG IIKTALLNMD RENREQYQVV IQAKDMGGQM GGLSGTTTVN
210 220 230 240 250
ITLTDVNDNP PRFPQSTYQF KTPESSPPGT PIGRIKASDA DVGENAEIEY
260 270 280 290 300
SITDGEGLDM FDVITDQETQ EGIITVKKLL DFEKKKVYTL KVEASNPYVE
310 320 330 340 350
PRFLYLGPFK DSATVRIVVE DVDEPPVFSK LAYILQIRED AQINTTIGSV
360 370 380 390 400
TAQDPDAARN PVKYSVDRHT DMDRIFNIDS GNGSIFTSKL LDRETLLWHN
410 420 430 440 450
ITVIATEINN PKQSSRVPLY IKVLDVNDNA PEFAEFYETF VCEKAKADQL
460 470 480 490 500
IQTLHAVDKD DPYSGHQFSF SLAPEAASGS NFTIQDNKDN TAGILTRKNG
510 520 530 540 550
YNRHEMSTYL LPVVISDNDY PVQSSTGTVT VRVCACDHHG NMQSCHAEAL
560 570 580 590 600
IHPTGLSTGA LVAILLCIVI LLGKLVLPAS YLPMVRGSHC YCDTLDLSAS

PIKAYSLI
Length:608
Mass (Da):67,403
Last modified:July 13, 2010 - v1
Checksum:iBEF5A4C6C5644583
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091898 Genomic DNA. No translation available.
AC113386 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514738; ENSP00000424843; ENSG00000113361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091898 Genomic DNA. No translation available.
AC113386 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RF86.
SMRiD6RF86. Positions 1-534.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265071.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514738; ENSP00000424843; ENSG00000113361.

Organism-specific databases

HGNCiHGNC:1765. CDH6.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118954.
HOGENOMiHOG000231252.
OrthoDBiEOG7GBFW7.

Miscellaneous databases

ChiTaRSiCDH6. human.
NextBioi35494405.

Gene expression databases

BgeeiD6RF86.
ExpressionAtlasiD6RF86. baseline and differential.

Family and domain databases

Gene3Di2.60.40.60. 5 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RF86_HUMAN
AccessioniPrimary (citable) accession number: D6RF86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 24, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.