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D6RF86

- D6RF86_HUMAN

UniProt

D6RF86 - D6RF86_HUMAN

Protein
Submitted name:

Cadherin-6

Gene

CDH6

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    GO - Biological processi

    1. homophilic cell adhesion Source: InterPro

    Keywords - Biological processi

    Cell adhesionSAAS annotation

    Keywords - Ligandi

    CalciumUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cadherin-6Imported
    Gene namesi
    Name:CDH6Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:1765. CDH6.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: InterPro

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiD6RF86.
    BgeeiD6RF86.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RF86.
    SMRiD6RF86. Positions 1-534.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000231252.
    OrthoDBiEOG7GBFW7.

    Family and domain databases

    Gene3Di2.60.40.60. 5 hits.
    InterProiIPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    [Graphical view]
    PfamiPF00028. Cadherin. 5 hits.
    [Graphical view]
    PRINTSiPR00205. CADHERIN.
    SMARTiSM00112. CA. 5 hits.
    [Graphical view]
    SUPFAMiSSF49313. SSF49313. 5 hits.
    PROSITEiPS00232. CADHERIN_1. 3 hits.
    PS50268. CADHERIN_2. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6RF86-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWNQFFLLEE YTGSDYQYVG KLHSDQDRGD GSLKYILSGD GAGDLFIINE    50
    NTGDIQATKR LDREEKPVYI LRAQAINRRT GRPVEPESEF IIKIHDINDN 100
    EPIFTKEVYT ATVPEMSDVG TFVVQVTATD ADDPTYGNSA KVVYSILQGQ 150
    PYFSVESETG IIKTALLNMD RENREQYQVV IQAKDMGGQM GGLSGTTTVN 200
    ITLTDVNDNP PRFPQSTYQF KTPESSPPGT PIGRIKASDA DVGENAEIEY 250
    SITDGEGLDM FDVITDQETQ EGIITVKKLL DFEKKKVYTL KVEASNPYVE 300
    PRFLYLGPFK DSATVRIVVE DVDEPPVFSK LAYILQIRED AQINTTIGSV 350
    TAQDPDAARN PVKYSVDRHT DMDRIFNIDS GNGSIFTSKL LDRETLLWHN 400
    ITVIATEINN PKQSSRVPLY IKVLDVNDNA PEFAEFYETF VCEKAKADQL 450
    IQTLHAVDKD DPYSGHQFSF SLAPEAASGS NFTIQDNKDN TAGILTRKNG 500
    YNRHEMSTYL LPVVISDNDY PVQSSTGTVT VRVCACDHHG NMQSCHAEAL 550
    IHPTGLSTGA LVAILLCIVI LLGKLVLPAS YLPMVRGSHC YCDTLDLSAS 600
    PIKAYSLI 608
    Length:608
    Mass (Da):67,403
    Last modified:July 13, 2010 - v1
    Checksum:iBEF5A4C6C5644583
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC091898 Genomic DNA. No translation available.
    AC113386 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000514738; ENSP00000424843; ENSG00000113361.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC091898 Genomic DNA. No translation available.
    AC113386 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RF86.
    SMRi D6RF86. Positions 1-534.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000514738 ; ENSP00000424843 ; ENSG00000113361 .

    Organism-specific databases

    HGNCi HGNC:1765. CDH6.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000231252.
    OrthoDBi EOG7GBFW7.

    Miscellaneous databases

    NextBioi 35494405.

    Gene expression databases

    ArrayExpressi D6RF86.
    Bgeei D6RF86.

    Family and domain databases

    Gene3Di 2.60.40.60. 5 hits.
    InterProi IPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    [Graphical view ]
    Pfami PF00028. Cadherin. 5 hits.
    [Graphical view ]
    PRINTSi PR00205. CADHERIN.
    SMARTi SM00112. CA. 5 hits.
    [Graphical view ]
    SUPFAMi SSF49313. SSF49313. 5 hits.
    PROSITEi PS00232. CADHERIN_1. 3 hits.
    PS50268. CADHERIN_2. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RF86_HUMAN
    AccessioniPrimary (citable) accession number: D6RF86
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3