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D6RF86

- D6RF86_HUMAN

UniProt

D6RF86 - D6RF86_HUMAN

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Protein
Submitted name:

Cadherin-6

Gene

CDH6

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. homophilic cell adhesion Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-6Imported
Gene namesi
Name:CDH6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:1765. CDH6.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiD6RF86.
ExpressionAtlasiD6RF86. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RF86.
SMRiD6RF86. Positions 1-534.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118954.
HOGENOMiHOG000231252.
OrthoDBiEOG7GBFW7.

Family and domain databases

Gene3Di2.60.40.60. 5 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6RF86-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWNQFFLLEE YTGSDYQYVG KLHSDQDRGD GSLKYILSGD GAGDLFIINE
60 70 80 90 100
NTGDIQATKR LDREEKPVYI LRAQAINRRT GRPVEPESEF IIKIHDINDN
110 120 130 140 150
EPIFTKEVYT ATVPEMSDVG TFVVQVTATD ADDPTYGNSA KVVYSILQGQ
160 170 180 190 200
PYFSVESETG IIKTALLNMD RENREQYQVV IQAKDMGGQM GGLSGTTTVN
210 220 230 240 250
ITLTDVNDNP PRFPQSTYQF KTPESSPPGT PIGRIKASDA DVGENAEIEY
260 270 280 290 300
SITDGEGLDM FDVITDQETQ EGIITVKKLL DFEKKKVYTL KVEASNPYVE
310 320 330 340 350
PRFLYLGPFK DSATVRIVVE DVDEPPVFSK LAYILQIRED AQINTTIGSV
360 370 380 390 400
TAQDPDAARN PVKYSVDRHT DMDRIFNIDS GNGSIFTSKL LDRETLLWHN
410 420 430 440 450
ITVIATEINN PKQSSRVPLY IKVLDVNDNA PEFAEFYETF VCEKAKADQL
460 470 480 490 500
IQTLHAVDKD DPYSGHQFSF SLAPEAASGS NFTIQDNKDN TAGILTRKNG
510 520 530 540 550
YNRHEMSTYL LPVVISDNDY PVQSSTGTVT VRVCACDHHG NMQSCHAEAL
560 570 580 590 600
IHPTGLSTGA LVAILLCIVI LLGKLVLPAS YLPMVRGSHC YCDTLDLSAS

PIKAYSLI
Length:608
Mass (Da):67,403
Last modified:July 13, 2010 - v1
Checksum:iBEF5A4C6C5644583
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC091898 Genomic DNA. No translation available.
AC113386 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514738; ENSP00000424843; ENSG00000113361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC091898 Genomic DNA. No translation available.
AC113386 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RF86.
SMRi D6RF86. Positions 1-534.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000514738 ; ENSP00000424843 ; ENSG00000113361 .

Organism-specific databases

HGNCi HGNC:1765. CDH6.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118954.
HOGENOMi HOG000231252.
OrthoDBi EOG7GBFW7.

Miscellaneous databases

NextBioi 35494405.

Gene expression databases

Bgeei D6RF86.
ExpressionAtlasi D6RF86. baseline and differential.

Family and domain databases

Gene3Di 2.60.40.60. 5 hits.
InterProi IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
[Graphical view ]
Pfami PF00028. Cadherin. 5 hits.
[Graphical view ]
PRINTSi PR00205. CADHERIN.
SMARTi SM00112. CA. 5 hits.
[Graphical view ]
SUPFAMi SSF49313. SSF49313. 5 hits.
PROSITEi PS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RF86_HUMAN
AccessioniPrimary (citable) accession number: D6RF86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3