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D6REX0

- D6REX0_HUMAN

UniProt

D6REX0 - D6REX0_HUMAN

Protein
Submitted name:

A disintegrin and metalloproteinase with thrombospondin motifs 12

Gene

ADAMTS12

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    A disintegrin and metalloproteinase with thrombospondin motifs 12Imported
    Gene namesi
    Name:ADAMTS12Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:14605. ADAMTS12.

    Expressioni

    Gene expression databases

    ArrayExpressiD6REX0.
    BgeeiD6REX0.

    Structurei

    3D structure databases

    ProteinModelPortaliD6REX0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000199502.

    Family and domain databases

    InterProiIPR002870. Peptidase_M12B_N.
    [Graphical view]
    PfamiPF01562. Pep_M12B_propep. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6REX0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPCAQRSWLA NLSVVAQLLN FGALCYGRQP QPGPVRFPDR RQEHFIKGLP    50
    EYHVVGPVRV DASGHFLSYG LHYPITSSRR KRDLDGSEDW VYYRISHEEK 100
    DLFFNLTVNQ GFLSNSYIME KRYGNLSHVK MMASSAPLCH LSGTVLQQGT 150
    RVGTAALSAC HGLTGFFQLP HGDFFIEPVK KHPLVEGGYH PHIVYRRQKV 200
    PETKEPTCGL KGIVTHMSSW VEESVLFFWL FY 232
    Length:232
    Mass (Da):26,426
    Last modified:July 13, 2010 - v1
    Checksum:i4D9BEBF1FBCB40E8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008880 Genomic DNA. No translation available.
    AC034232 Genomic DNA. No translation available.
    AC109491 Genomic DNA. No translation available.
    AC139777 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000515401; ENSP00000421638; ENSG00000151388.
    UCSCiuc003jib.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008880 Genomic DNA. No translation available.
    AC034232 Genomic DNA. No translation available.
    AC109491 Genomic DNA. No translation available.
    AC139777 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6REX0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000515401 ; ENSP00000421638 ; ENSG00000151388 .
    UCSCi uc003jib.1. human.

    Organism-specific databases

    HGNCi HGNC:14605. ADAMTS12.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000199502.

    Miscellaneous databases

    ChiTaRSi ADAMTS12. human.
    NextBioi 35494305.

    Gene expression databases

    ArrayExpressi D6REX0.
    Bgeei D6REX0.

    Family and domain databases

    InterProi IPR002870. Peptidase_M12B_N.
    [Graphical view ]
    Pfami PF01562. Pep_M12B_propep. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6REX0_HUMAN
    AccessioniPrimary (citable) accession number: D6REX0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3