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Protein
Submitted name:

A disintegrin and metalloproteinase with thrombospondin motifs 12

Gene

ADAMTS12

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
A disintegrin and metalloproteinase with thrombospondin motifs 12Imported
Gene namesi
Name:ADAMTS12Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:14605. ADAMTS12.

Expressioni

Gene expression databases

BgeeiD6REX0.
ExpressionAtlasiD6REX0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000422554.

Structurei

3D structure databases

ProteinModelPortaliD6REX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118885.
HOGENOMiHOG000199502.

Family and domain databases

InterProiIPR002870. Peptidase_M12B_N.
[Graphical view]
PfamiPF01562. Pep_M12B_propep. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6REX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPCAQRSWLA NLSVVAQLLN FGALCYGRQP QPGPVRFPDR RQEHFIKGLP
60 70 80 90 100
EYHVVGPVRV DASGHFLSYG LHYPITSSRR KRDLDGSEDW VYYRISHEEK
110 120 130 140 150
DLFFNLTVNQ GFLSNSYIME KRYGNLSHVK MMASSAPLCH LSGTVLQQGT
160 170 180 190 200
RVGTAALSAC HGLTGFFQLP HGDFFIEPVK KHPLVEGGYH PHIVYRRQKV
210 220 230
PETKEPTCGL KGIVTHMSSW VEESVLFFWL FY
Length:232
Mass (Da):26,426
Last modified:July 13, 2010 - v1
Checksum:i4D9BEBF1FBCB40E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008880 Genomic DNA. No translation available.
AC034232 Genomic DNA. No translation available.
AC109491 Genomic DNA. No translation available.
AC139777 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000515401; ENSP00000421638; ENSG00000151388.
UCSCiuc003jib.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008880 Genomic DNA. No translation available.
AC034232 Genomic DNA. No translation available.
AC109491 Genomic DNA. No translation available.
AC139777 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6REX0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000422554.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000515401; ENSP00000421638; ENSG00000151388.
UCSCiuc003jib.1. human.

Organism-specific databases

HGNCiHGNC:14605. ADAMTS12.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118885.
HOGENOMiHOG000199502.

Miscellaneous databases

ChiTaRSiADAMTS12. human.
NextBioi35494305.

Gene expression databases

BgeeiD6REX0.
ExpressionAtlasiD6REX0. baseline and differential.

Family and domain databases

InterProiIPR002870. Peptidase_M12B_N.
[Graphical view]
PfamiPF01562. Pep_M12B_propep. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6REX0_HUMAN
AccessioniPrimary (citable) accession number: D6REX0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 24, 2015
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.