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Protein
Submitted name:

Peptidyl-prolyl cis-trans isomerase CWC27 homolog

Gene

CWC27

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins.SAAS annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Peptidyl-prolyl cis-trans isomerase CWC27 homologImported
Gene namesi
Name:CWC27Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000153015.15
HGNCiHGNC:10664 CWC27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000153015

PTM / Processingi

Proteomic databases

MaxQBiD6REK3
PeptideAtlasiD6REK3
PRIDEiD6REK3

Expressioni

Gene expression databases

BgeeiENSG00000153015
ExpressionAtlasiD6REK3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6REK3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 166PPIase cyclophilin-typeInterPro annotationAdd BLAST148

Phylogenomic databases

eggNOGiKOG0885 Eukaryota
COG0652 LUCA
GeneTreeiENSGT00760000119072

Family and domain databases

Gene3Di2.40.100.10, 1 hit
InterProiView protein in InterPro
IPR029000 Cyclophilin-like_dom_sf
IPR024936 Cyclophilin-type_PPIase
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
PANTHERiPTHR11071 PTHR11071, 1 hit
PfamiView protein in Pfam
PF00160 Pro_isomerase, 1 hit
PRINTSiPR00153 CSAPPISMRASE
SUPFAMiSSF50891 SSF50891, 1 hit
PROSITEiView protein in PROSITE
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D6REK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNIYIQEPP TNGKVLLKTT AGDIDIELWS KEAPKACRNF IQLCLEAYYD
60 70 80 90 100
NTIFHRVVPG FIVQGGDPTG TGSGGESIYG APFKDEFHSR LRFNRRGLVA
110 120 130 140 150
MANAGSHDNG SQFFFTLGRA DELNNKHTIF GKVTGDTVYN MLRLSEVDID
160 170 180 190 200
DDERPHNPHK IKSCEVLFNP FDDIIPREIK RLKKEKPEEE VKKLKPKGTK
210 220 230 240 250
NFSLLSFGEE AEEEEEEVNR VSQSMKGKSK SSHDLLKDDP HLSSVPVVES
260 270 280 290 300
EKGDAPDLVD DGEDESAEHD EYIDGDEKNL MRERIAKKLK KDTSANVKSA
310 320 330 340 350
GEGEVEKKSV SRSPPSLCLY LDYWIQLSRI TQAYTSWYYY GFLDSSLSCV
360 370 380
SSASLLLTRH NVYFTLQTHS TDHLAACFFM K
Length:381
Mass (Da):42,996
Last modified:July 13, 2010 - v1
Checksum:i822BB8D82C8952A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008898 Genomic DNA No translation available.
AC092354 Genomic DNA No translation available.
AC109465 Genomic DNA No translation available.
RefSeqiNP_001284574.1, NM_001297645.1
UniGeneiHs.371372

Genome annotation databases

EnsembliENST00000508024; ENSP00000426802; ENSG00000153015
GeneIDi10283
UCSCiuc003jtl.4 human

Similar proteinsi

Entry informationi

Entry nameiD6REK3_HUMAN
AccessioniPrimary (citable) accession number: D6REK3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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