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D6RE63

- D6RE63_HUMAN

UniProt

D6RE63 - D6RE63_HUMAN

Protein
Submitted name:

Nephronectin

Gene

NPNT

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. branching involved in ureteric bud morphogenesis Source: Ensembl
    2. cell-cell adhesion mediated by integrin Source: Ensembl
    3. cell-matrix adhesion Source: Ensembl
    4. cellular response to tumor necrosis factor Source: Ensembl
    5. establishment of protein localization Source: Ensembl
    6. extracellular matrix organization Source: Ensembl
    7. pilomotor reflex Source: Ensembl
    8. positive regulation of alkaline phosphatase activity Source: Ensembl
    9. positive regulation of cell-substrate adhesion Source: Ensembl
    10. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
    11. positive regulation of osteoblast differentiation Source: Ensembl
    12. positive regulation of smooth muscle contraction Source: Ensembl
    13. positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Source: Ensembl
    14. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    NephronectinImported
    Gene namesi
    Name:NPNTImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:27405. NPNT.

    Subcellular locationi

    GO - Cellular componenti

    1. basement membrane Source: Ensembl
    2. integrin alpha8-beta1 complex Source: Ensembl
    3. smooth muscle contractile fiber Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiD6RE63.
    BgeeiD6RE63.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RE63.
    SMRiD6RE63. Positions 1-61.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view]
    SUPFAMiSSF57184. SSF57184. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    D6RE63-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTYGSYKCY CLNGYMLMPD GSCSSALTCS MANCQYGCDV VKGQIRCQCP   50
    SPGLQLAPDG R 61
    Length:61
    Mass (Da):6,556
    Last modified:July 13, 2010 - v1
    Checksum:i1AF1395B80A24DA6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei61 – 611Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093782 Genomic DNA. No translation available.
    AC109361 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000504304; ENSP00000426951; ENSG00000168743.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093782 Genomic DNA. No translation available.
    AC109361 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RE63.
    SMRi D6RE63. Positions 1-61.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000504304 ; ENSP00000426951 ; ENSG00000168743 .

    Organism-specific databases

    HGNCi HGNC:27405. NPNT.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi NPNT. human.
    NextBioi 35494152.

    Gene expression databases

    ArrayExpressi D6RE63.
    Bgeei D6RE63.

    Family and domain databases

    InterProi IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view ]
    SUPFAMi SSF57184. SSF57184. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RE63_HUMAN
    AccessioniPrimary (citable) accession number: D6RE63
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3