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D6RE63

- D6RE63_HUMAN

UniProt

D6RE63 - D6RE63_HUMAN

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Protein
Submitted name:

Nephronectin

Gene
NPNT
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. branching involved in ureteric bud morphogenesis Source: Ensembl
  2. cell-cell adhesion mediated by integrin Source: Ensembl
  3. cell-matrix adhesion Source: Ensembl
  4. cellular response to tumor necrosis factor Source: Ensembl
  5. establishment of protein localization Source: Ensembl
  6. extracellular matrix organization Source: Ensembl
  7. pilomotor reflex Source: Ensembl
  8. positive regulation of alkaline phosphatase activity Source: Ensembl
  9. positive regulation of cell-substrate adhesion Source: Ensembl
  10. positive regulation of ERK1 and ERK2 cascade Source: Ensembl
  11. positive regulation of osteoblast differentiation Source: Ensembl
  12. positive regulation of smooth muscle contraction Source: Ensembl
  13. positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Source: Ensembl
  14. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NephronectinImported
Gene namesi
Name:NPNTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:27405. NPNT.

Subcellular locationi

GO - Cellular componenti

  1. basement membrane Source: Ensembl
  2. integrin alpha8-beta1 complex Source: Ensembl
  3. smooth muscle contractile fiber Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiD6RE63.
BgeeiD6RE63.

Structurei

3D structure databases

ProteinModelPortaliD6RE63.
SMRiD6RE63. Positions 1-61.

Family & Domainsi

Family and domain databases

InterProiIPR009030. Growth_fac_rcpt_N_dom.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.

Sequencei

Sequence statusi: Fragment.

D6RE63-1 [UniParc]FASTAAdd to Basket

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MNTYGSYKCY CLNGYMLMPD GSCSSALTCS MANCQYGCDV VKGQIRCQCP   50
SPGLQLAPDG R 61
Length:61
Mass (Da):6,556
Last modified:July 13, 2010 - v1
Checksum:i1AF1395B80A24DA6
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei61 – 611Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000504304; ENSP00000426951; ENSG00000168743.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093782 Genomic DNA. No translation available.
AC109361 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RE63.
SMRi D6RE63. Positions 1-61.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000504304 ; ENSP00000426951 ; ENSG00000168743 .

Organism-specific databases

HGNCi HGNC:27405. NPNT.
GenAtlasi Search...

Miscellaneous databases

ChiTaRSi NPNT. human.
NextBioi 35494152.

Gene expression databases

ArrayExpressi D6RE63.
Bgeei D6RE63.

Family and domain databases

InterProi IPR009030. Growth_fac_rcpt_N_dom.
[Graphical view ]
SUPFAMi SSF57184. SSF57184. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RE63_HUMAN
AccessioniPrimary (citable) accession number: D6RE63
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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