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Protein
Submitted name:

Ephrin-A5

Gene

EFNA5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin-A5Imported
Gene namesi
Name:EFNA5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000184349.12
HGNCiHGNC:3225 EFNA5

Subcellular locationi

Keywords - Cellular componenti

MembraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184349

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500308734621 – 201Sequence analysisAdd BLAST181

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi62 ↔ 102PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiD6RDV5
PeptideAtlasiD6RDV5
PRIDEiD6RDV5

Expressioni

Gene expression databases

BgeeiENSG00000184349
ExpressionAtlasiD6RDV5 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliD6RDV5
SMRiD6RDV5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 162Ephrin RBDInterPro annotationAdd BLAST134

Sequence similaritiesi

Belongs to the ephrin family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000015107
HOGENOMiHOG000234373

Family and domain databases

CDDicd10425 Ephrin-A_Ectodomain, 1 hit
Gene3Di2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR008972 Cupredoxin
IPR031328 Ephrin
IPR034252 Ephrin-A_Ecto
IPR019765 Ephrin_CS
IPR001799 Ephrin_RBD
PANTHERiPTHR11304 PTHR11304, 2 hits
PfamiView protein in Pfam
PF00812 Ephrin, 1 hit
PRINTSiPR01347 EPHRIN
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002533 Ephrin, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
PROSITEiView protein in PROSITE
PS01299 EPHRIN_RBD_1, 1 hit
PS51551 EPHRIN_RBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

D6RDV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHVEMLTLV FLVLWMCVFS QDPGSKAVAD RYAVYWNSSN PRFQRGDYHI
60 70 80 90 100
DVCINDYLDV FCPHYEDSVP EDKTERYVLY MVNFDGYSAC DHTSKGFKRW
110 120 130 140 150
ECNRPHSPNG PLKFSEKFQL FTPFSLGFEF RPGREYFYIS SAIPDNGRRS
160 170 180 190 200
CLKLKVFVRP TNDTVHESAE PSRGENAAQT PRIPSRLLAI LLFLLAMLLT

L
Length:201
Mass (Da):23,296
Last modified:July 13, 2010 - v1
Checksum:i1AF418B698BAEAA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008796 Genomic DNA No translation available.
AC008800 Genomic DNA No translation available.
AC008952 Genomic DNA No translation available.
AC010227 Genomic DNA No translation available.
AC011349 Genomic DNA No translation available.
AC024587 Genomic DNA No translation available.
KC877063 Genomic DNA No translation available.
RefSeqiXP_006714628.1, XM_006714565.2
UniGeneiHs.288741

Genome annotation databases

EnsembliENST00000509503; ENSP00000426989; ENSG00000184349
GeneIDi1946
UCSCiuc063fvw.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RDV5_HUMAN
AccessioniPrimary (citable) accession number: D6RDV5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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