Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Mothers against decapentaplegic homolog 1

Gene

SMAD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mothers against decapentaplegic homolog 1Imported
Gene namesi
Name:SMAD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000170365.9.
HGNCiHGNC:6767. SMAD1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170365.

PTM / Processingi

Proteomic databases

MaxQBiD6RDN7.
PeptideAtlasiD6RDN7.
PRIDEiD6RDN7.

Expressioni

Gene expression databases

BgeeiENSG00000170365.
ExpressionAtlasiD6RDN7. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 112MH1InterPro annotationAdd BLAST101

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili34 – 54Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.
HOGENOMiHOG000198838.

Family and domain databases

Gene3Di3.90.520.10. 1 hit.
InterProiView protein in InterPro
IPR013790. Dwarfin.
IPR003619. MAD_homology1_Dwarfin-type.
IPR013019. MAD_homology_MH1.
IPR036578. SMAD_MH1_sf.
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiView protein in Pfam
PF03165. MH1. 1 hit.
SMARTiView protein in SMART
SM00523. DWA. 1 hit.
SUPFAMiSSF56366. SSF56366. 1 hit.
PROSITEiView protein in PROSITE
PS51075. MH1. 1 hit.

Sequencei

Sequence statusi: Fragment.

D6RDN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE
60 70 80 90 100
LEKALSCPGQ PSNCVTIPRS LDGRLQVSHR KGLPHVIYCR VWRWPDLQSH
110
HELKPLECCE FP
Length:112
Mass (Da):12,826
Last modified:July 13, 2010 - v1
Checksum:i854A013F6E86639B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei112Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093796 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000514831; ENSP00000425270; ENSG00000170365.
UCSCiuc062zzn.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RDN7_HUMAN
AccessioniPrimary (citable) accession number: D6RDN7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: March 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported