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Protein
Submitted name:

Probable E3 ubiquitin-protein ligase HERC4

Gene

HERC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Probable E3 ubiquitin-protein ligase HERC4Imported
Gene namesi
Name:HERC4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000148634.15.
HGNCiHGNC:24521. HERC4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148634.

PTM / Processingi

Proteomic databases

MaxQBiD6RCL5.
PeptideAtlasiD6RCL5.
PRIDEiD6RCL5.

Expressioni

Gene expression databases

BgeeiENSG00000148634.
ExpressionAtlasiD6RCL5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RCL5.
SMRiD6RCL5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 52RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati53 – 102RCC1PROSITE-ProRule annotationAdd BLAST50
Repeati103 – 179RCC1PROSITE-ProRule annotationAdd BLAST77
Repeati180 – 232RCC1PROSITE-ProRule annotationAdd BLAST53

Phylogenomic databases

GeneTreeiENSGT00900000140848.
HOGENOMiHOG000020996.

Family and domain databases

Gene3Di2.130.10.30. 2 hits.
InterProiView protein in InterPro
IPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
PfamiView protein in Pfam
PF00415. RCC1. 4 hits.
PRINTSiPR00633. RCCNDNSATION.
SUPFAMiSSF50985. SSF50985. 1 hit.
PROSITEiView protein in PROSITE
PS00626. RCC1_2. 2 hits.
PS50012. RCC1_3. 4 hits.

Sequencei

Sequence statusi: Fragment.

D6RCL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCWGNASFG QLGLGGIDEE IVLEPRKSDF FINKRVRDVG CGLRHTVFVL
60 70 80 90 100
DDGTVYTCGC NDLGQLGHEK SRKKPEQVVA LDAQNIVAVS CGEAHTLALN
110 120 130 140 150
DKGQVYAWGL DSDGQLGLVG SEECIRVPSC FPKIMCVDSL VRICSGLSYG
160 170 180 190 200
RIRNIKSLSD IQIVQVACGY YHSLALSKAS EVFCWGQNKY GQLGLGTDCK
210 220 230 240
KQTSPQLLKS LLGIPFMQVA AGGAHSFVLT LSGAIFGWGR
Length:240
Mass (Da):25,895
Last modified:July 13, 2010 - v1
Checksum:i188C67596F9C9883
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024258 Genomic DNA. No translation available.
AL133551 Genomic DNA. No translation available.
AL356741 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000513996; ENSP00000427191; ENSG00000148634.
UCSCiuc057tpv.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RCL5_HUMAN
AccessioniPrimary (citable) accession number: D6RCL5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 25, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported