ID   D6RCJ2_MOUSE            Unreviewed;        62 AA.
AC   D6RCJ2;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Nicastrin {ECO:0000313|Ensembl:ENSMUSP00000119128.2};
GN   Name=Ncstn {ECO:0000313|Ensembl:ENSMUSP00000119128.2,
GN   ECO:0000313|MGI:MGI:1891700};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119128.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000119128.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119128.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000119128.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119128.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   ProteomicsDB; 334675; -.
DR   Antibodypedia; 20490; 596 antibodies from 44 providers.
DR   Ensembl; ENSMUST00000140643.8; ENSMUSP00000119128.2; ENSMUSG00000003458.13.
DR   Ensembl; ENSMUST00000146137.8; ENSMUSP00000120663.2; ENSMUSG00000003458.13.
DR   AGR; MGI:1891700; -.
DR   MGI; MGI:1891700; Ncstn.
DR   VEuPathDB; HostDB:ENSMUSG00000003458; -.
DR   GeneTree; ENSGT00390000014633; -.
DR   HOGENOM; CLU_2903567_0_0_1; -.
DR   OMA; ECVYPGV; -.
DR   ChiTaRS; Ncstn; mouse.
DR   Proteomes; UP000000589; Chromosome 1.
DR   Bgee; ENSMUSG00000003458; Expressed in spermatocyte and 207 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016485; P:protein processing; IEA:InterPro.
DR   InterPro; IPR008710; Nicastrin.
DR   PANTHER; PTHR21092; NICASTRIN; 1.
DR   PANTHER; PTHR21092:SF0; NICASTRIN; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   62 AA;  6410 MW;  D1E33F6B0B6F1121 CRC64;
     MATTRGGSGP DPGSRGLLLL SFSVVLAGLC GGNSVERKIY IPLNKTAPCV RLLNATHQIG
     CQ
//