D6RCJ2 (D6RCJ2_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nicastrin Ensembl ENSMUSP00000120663 Ensembl ENSMUSP00000119128

Gene names

Name:

Ncstn Ensembl ENSMUSP00000120663 Ensembl ENSMUSP00000119128 MGI 1891700

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000119128

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	62 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000120663 Ensembl ENSMUSP00000119128

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	T cell proliferation Inferred from mutant phenotype PubMed 17913918. Source: MGI beta-amyloid metabolic process Inferred from mutant phenotype PubMed 17913918. Source: MGI epithelial cell proliferation Inferred from mutant phenotype PubMed 17913918. Source: MGI myeloid cell homeostasis Inferred from mutant phenotype PubMed 17913918. Source: MGI protein processing Inferred from electronic annotation. Source: InterPro
Cellular_component	Golgi apparatus Inferred from direct assay PubMed 12646573. Source: MGI endoplasmic reticulum Inferred from direct assay PubMed 12646573. Source: MGI integral to membrane Inferred from electronic annotation. Source: InterPro lysosomal membrane Inferred from electronic annotation. Source: Compara plasma membrane Inferred from direct assay PubMed 12646573. Source: MGI
Molecular_function	endopeptidase activity Inferred from mutant phenotype PubMed 17913918. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D6RCJ2 [UniParc]. Last modified July 13, 2010. Version 1. Checksum: D1E33F6B0B6F1121	FASTA	62	6,410
	10 20 30 40 50 60 MATTRGGSGP DPGSRGLLLL SFSVVLAGLC GGNSVERKIY IPLNKTAPCV RLLNATHQIG CQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000120663 Ensembl ENSMUSP00000119128.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000120663 Ensembl ENSMUSP00000119128.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC158930 Genomic DNA. No translation available.
IPI	IPI00894997.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000140643; ENSMUSP00000119128; ENSMUSG00000003458. ENSMUST00000146137; ENSMUSP00000120663; ENSMUSG00000003458.
Organism-specific databases
MGI	MGI:1891700. Ncstn.
Phylogenomic databases
GeneTree	ENSGT00390000014633.
HOGENOM	HOG000185997.
Family and domain databases
InterPro	IPR008710. Nicastrin. [Graphical view]
PANTHER	PTHR21092. PTHR21092. 1 hit.
ProtoNet	Search...
Other
NextBio	35551869.
SOURCE	Search...

Entry information

Entry name

D6RCJ2_MOUSE

Accession

Primary (citable) accession number: D6RCJ2

Entry history

Integrated into UniProtKB/TrEMBL:	July 13, 2010
Last sequence update:	July 13, 2010
Last modified:	April 3, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)