Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D6RCG7

- D6RCG7_MOUSE

UniProt

D6RCG7 - D6RCG7_MOUSE

Protein
Submitted name:

Caspase-12

Gene

Casp12

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. cysteine-type endopeptidase activity Source: RefGenome
    2. protein binding Source: MGI

    GO - Biological processi

    1. apoptotic process Source: MGI
    2. endoplasmic reticulum unfolded protein response Source: MGI
    3. intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Source: MGI
    4. regulation of apoptotic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Caspase-12Imported
    Gene namesi
    Name:Casp12Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1312922. Casp12.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: RefGenome
    2. endoplasmic reticulum Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiD6RCG7.
    BgeeiD6RCG7.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RCG7.
    SMRiD6RCG7. Positions 164-224.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains CARD domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00700000104134.
    HOGENOMiHOG000234399.

    Family and domain databases

    Gene3Di1.10.533.10. 1 hit.
    3.40.50.1460. 1 hit.
    InterProiIPR001315. CARD.
    IPR029030. Caspase-like_dom.
    IPR011029. DEATH-like_dom.
    IPR011600. Pept_C14_caspase.
    IPR001309. Pept_C14_ICE_p20.
    IPR015917. Pept_C14A_p45_core.
    [Graphical view]
    PfamiPF00619. CARD. 1 hit.
    PF00656. Peptidase_C14. 1 hit.
    [Graphical view]
    PRINTSiPR00376. IL1BCENZYME.
    SMARTiSM00114. CARD. 1 hit.
    [Graphical view]
    SUPFAMiSSF47986. SSF47986. 1 hit.
    PROSITEiPS50209. CARD. 1 hit.
    PS50208. CASPASE_P20. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6RCG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAARRTHERD PIYKIKGLAK DMLDGVFDDL VEKNVLNGDE LLKIGESASF    50
    ILNKAENLVE NFLEKTDMAG KIFAGHIANS QEQLSLQFSN DEDDGPQKIC 100
    TPSSPSESKR KVEDDEMEVN AGLAHESHLM LTAPHGLQSS EVQDTLKLCP 150
    RDQFCKIKTE RAKEIYPVME KEGRTRLALI ICNKKFDYLF DRDNADTDIL 200
    NMQELLENLG YSVVLKENLT AQSLFRKWRQ S 231
    Length:231
    Mass (Da):26,266
    Last modified:July 13, 2010 - v1
    Checksum:i4B43D82EFC2D884A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC104914 Genomic DNA. No translation available.
    AC141637 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000151788; ENSMUSP00000121565; ENSMUSG00000025887.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC104914 Genomic DNA. No translation available.
    AC141637 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RCG7.
    SMRi D6RCG7. Positions 164-224.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000151788 ; ENSMUSP00000121565 ; ENSMUSG00000025887 .

    Organism-specific databases

    MGIi MGI:1312922. Casp12.

    Phylogenomic databases

    GeneTreei ENSGT00700000104134.
    HOGENOMi HOG000234399.

    Miscellaneous databases

    NextBioi 35551845.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi D6RCG7.
    Bgeei D6RCG7.

    Family and domain databases

    Gene3Di 1.10.533.10. 1 hit.
    3.40.50.1460. 1 hit.
    InterProi IPR001315. CARD.
    IPR029030. Caspase-like_dom.
    IPR011029. DEATH-like_dom.
    IPR011600. Pept_C14_caspase.
    IPR001309. Pept_C14_ICE_p20.
    IPR015917. Pept_C14A_p45_core.
    [Graphical view ]
    Pfami PF00619. CARD. 1 hit.
    PF00656. Peptidase_C14. 1 hit.
    [Graphical view ]
    PRINTSi PR00376. IL1BCENZYME.
    SMARTi SM00114. CARD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47986. SSF47986. 1 hit.
    PROSITEi PS50209. CARD. 1 hit.
    PS50208. CASPASE_P20. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiD6RCG7_MOUSE
    AccessioniPrimary (citable) accession number: D6RCG7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3