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Protein
Submitted name:

Protocadherin Fat 1

Gene

FAT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin Fat 1Imported
Gene namesi
Name:FAT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:3595. FAT1.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000083857.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500308733322 – 488Sequence analysisAdd BLAST467

Proteomic databases

MaxQBiD6RCE4.
PaxDbiD6RCE4.
PeptideAtlasiD6RCE4.
PRIDEiD6RCE4.

Expressioni

Gene expression databases

BgeeiENSG00000083857.
ExpressionAtlasiD6RCE4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RCE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 147CAInterPro annotationAdd BLAST87
Domaini171 – 255CAInterPro annotationAdd BLAST85
Domaini276 – 358CAInterPro annotationAdd BLAST83
Domaini385 – 461CAInterPro annotationAdd BLAST77

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1219. Eukaryota.
ENOG410XPEI. LUCA.
GeneTreeiENSGT00760000118805.
HOGENOMiHOG000046499.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
PfamiView protein in Pfam
PF00028. Cadherin. 1 hit.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 4 hits.
SUPFAMiSSF49313. SSF49313. 4 hits.

Sequencei

Sequence statusi: Fragment.

D6RCE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRHLALLLL LLLLFQHFGD SDGSQRLEQT PLQFTHLEYN VTVQENSAAK
60 70 80 90 100
TYVGHPVKMG VYITHPAWEV RYKIVSGDSE NLFKAEEYIL GDFCFLRIRT
110 120 130 140 150
KGGNTAILNR EVKDHYTLIV KALEKNTNVE ARTKVRVQVL DTNDLRPLFS
160 170 180 190 200
PTSYSVSLPE NTAIRTSIAR VSATDADIGT NGEFYYSFKD RTDMFAIHPT
210 220 230 240 250
SGVIVLTGRL DYLETKLYEM EILAADRGMK LYGSSGISSM AKLTVHIEQA
260 270 280 290 300
NECAPVITAV TLSPSELDRD PAYAIVTVDD CDQGANGDIA SLSIVAGDLL
310 320 330 340 350
QQFRTVRSFP GSKEYKVKAI GGIDWDSHPF GYNLTLQAKD KGTPPQFSSV
360 370 380 390 400
KVIHVTSPQF KAGPVKFEKD VYRAEISEFA PPNTPVVMVK AIPAYSHLRY
410 420 430 440 450
VFKSTPGKAK FSLNYNTGLI SILEPVKRQQ AAHFELEVTT SDRKASTKVL
460 470 480
VKVLGANSNP PEFTQTAYKA AFDENVPIGT TVMSLSAV
Length:488
Mass (Da):53,921
Last modified:July 13, 2010 - v1
Checksum:i70A24EAA1C0692F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei488Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107050 Genomic DNA. No translation available.
AC110761 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000509647; ENSP00000423736; ENSG00000083857.
UCSCiuc063bpe.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD6RCE4_HUMAN
AccessioniPrimary (citable) accession number: D6RCE4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 5, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported