Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

D6RCE4

- D6RCE4_HUMAN

UniProt

D6RCE4 - D6RCE4_HUMAN

Protein
Submitted name:

Protocadherin Fat 1

Gene

FAT1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    GO - Biological processi

    1. actin filament organization Source: Ensembl
    2. establishment or maintenance of cell polarity Source: Ensembl
    3. homophilic cell adhesion Source: InterPro
    4. single organismal cell-cell adhesion Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protocadherin Fat 1Imported
    Gene namesi
    Name:FAT1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:3595. FAT1.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: Ensembl
    2. filopodium Source: Ensembl
    3. integral component of membrane Source: UniProtKB-KW
    4. lamellipodium Source: Ensembl

    Keywords - Cellular componenti

    MembraneSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiD6RCE4.
    BgeeiD6RCE4.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RCE4.
    SMRiD6RCE4. Positions 29-488.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000046499.

    Family and domain databases

    Gene3Di2.60.40.60. 3 hits.
    InterProiIPR002126. Cadherin.
    IPR015919. Cadherin-like.
    [Graphical view]
    PfamiPF00028. Cadherin. 1 hit.
    [Graphical view]
    PRINTSiPR00205. CADHERIN.
    SMARTiSM00112. CA. 4 hits.
    [Graphical view]
    SUPFAMiSSF49313. SSF49313. 4 hits.
    PROSITEiPS50268. CADHERIN_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D6RCE4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRHLALLLL LLLLFQHFGD SDGSQRLEQT PLQFTHLEYN VTVQENSAAK    50
    TYVGHPVKMG VYITHPAWEV RYKIVSGDSE NLFKAEEYIL GDFCFLRIRT 100
    KGGNTAILNR EVKDHYTLIV KALEKNTNVE ARTKVRVQVL DTNDLRPLFS 150
    PTSYSVSLPE NTAIRTSIAR VSATDADIGT NGEFYYSFKD RTDMFAIHPT 200
    SGVIVLTGRL DYLETKLYEM EILAADRGMK LYGSSGISSM AKLTVHIEQA 250
    NECAPVITAV TLSPSELDRD PAYAIVTVDD CDQGANGDIA SLSIVAGDLL 300
    QQFRTVRSFP GSKEYKVKAI GGIDWDSHPF GYNLTLQAKD KGTPPQFSSV 350
    KVIHVTSPQF KAGPVKFEKD VYRAEISEFA PPNTPVVMVK AIPAYSHLRY 400
    VFKSTPGKAK FSLNYNTGLI SILEPVKRQQ AAHFELEVTT SDRKASTKVL 450
    VKVLGANSNP PEFTQTAYKA AFDENVPIGT TVMSLSAV 488
    Length:488
    Mass (Da):53,921
    Last modified:July 13, 2010 - v1
    Checksum:i70A24EAA1C0692F8
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei488 – 4881Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC107050 Genomic DNA. No translation available.
    AC110761 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000509647; ENSP00000423736; ENSG00000083857.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC107050 Genomic DNA. No translation available.
    AC110761 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RCE4.
    SMRi D6RCE4. Positions 29-488.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000509647 ; ENSP00000423736 ; ENSG00000083857 .

    Organism-specific databases

    HGNCi HGNC:3595. FAT1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000046499.

    Miscellaneous databases

    ChiTaRSi FAT1. human.
    NextBioi 35493833.

    Gene expression databases

    ArrayExpressi D6RCE4.
    Bgeei D6RCE4.

    Family and domain databases

    Gene3Di 2.60.40.60. 3 hits.
    InterProi IPR002126. Cadherin.
    IPR015919. Cadherin-like.
    [Graphical view ]
    Pfami PF00028. Cadherin. 1 hit.
    [Graphical view ]
    PRINTSi PR00205. CADHERIN.
    SMARTi SM00112. CA. 4 hits.
    [Graphical view ]
    SUPFAMi SSF49313. SSF49313. 4 hits.
    PROSITEi PS50268. CADHERIN_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.D., Yates J.R.
      J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RCE4_HUMAN
    AccessioniPrimary (citable) accession number: D6RCE4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3