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D6RCD5

- D6RCD5_HUMAN

UniProt

D6RCD5 - D6RCD5_HUMAN

Protein
Submitted name:

Peptidyl-glycine alpha-amidating monooxygenase

Gene

PAM

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: Ensembl
    2. peptidylamidoglycolate lyase activity Source: Ensembl
    3. zinc ion binding Source: Ensembl

    GO - Biological processi

    1. central nervous system development Source: Ensembl
    2. heart development Source: Ensembl
    3. lactation Source: Ensembl
    4. limb development Source: Ensembl
    5. long-chain fatty acid metabolic process Source: Ensembl
    6. maternal process involved in female pregnancy Source: Ensembl
    7. odontogenesis Source: Ensembl
    8. ovulation cycle process Source: Ensembl
    9. peptide amidation Source: Ensembl
    10. protein amidation Source: Ensembl
    11. protein homooligomerization Source: Ensembl
    12. regulation of actin cytoskeleton organization Source: Ensembl
    13. regulation of protein secretion Source: Ensembl
    14. regulation of transcription from RNA polymerase II promoter Source: Ensembl
    15. response to copper ion Source: Ensembl
    16. response to drug Source: Ensembl
    17. response to estradiol Source: Ensembl
    18. response to glucocorticoid Source: Ensembl
    19. response to hypoxia Source: Ensembl
    20. response to pH Source: Ensembl
    21. toxin metabolic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Peptidyl-glycine alpha-amidating monooxygenaseImported
    Gene namesi
    Name:PAMImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:8596. PAM.

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: Ensembl
    2. extracellular space Source: Ensembl
    3. neuron projection Source: Ensembl
    4. perikaryon Source: Ensembl
    5. perinuclear region of cytoplasm Source: Ensembl
    6. plasma membrane Source: Ensembl
    7. secretory granule membrane Source: Ensembl
    8. trans-Golgi network Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiD6RCD5.
    BgeeiD6RCD5.

    Sequencei

    Sequence statusi: Fragment.

    D6RCD5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGRVPSLLV LLVFPSSCLA FRSPLSVFKR FKETTRPFSN ECLGTTRPVV   50
    PID 53
    Length:53
    Mass (Da):5,882
    Last modified:July 13, 2010 - v1
    Checksum:i32B2CEBFD2D4ECD5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei53 – 531Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008501 Genomic DNA. No translation available.
    AC008779 Genomic DNA. No translation available.
    AC010250 Genomic DNA. No translation available.
    AC113373 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000509832; ENSP00000423763; ENSG00000145730.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008501 Genomic DNA. No translation available.
    AC008779 Genomic DNA. No translation available.
    AC010250 Genomic DNA. No translation available.
    AC113373 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000509832 ; ENSP00000423763 ; ENSG00000145730 .

    Organism-specific databases

    HGNCi HGNC:8596. PAM.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi PAM. human.
    NextBioi 35493824.

    Gene expression databases

    ArrayExpressi D6RCD5.
    Bgeei D6RCD5.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RCD5_HUMAN
    AccessioniPrimary (citable) accession number: D6RCD5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3