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D6RCD5

- D6RCD5_HUMAN

UniProt

D6RCD5 - D6RCD5_HUMAN

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Protein
Submitted name:

Peptidyl-glycine alpha-amidating monooxygenase

Gene

PAM

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: Ensembl
  2. peptidylamidoglycolate lyase activity Source: Ensembl
  3. zinc ion binding Source: Ensembl

GO - Biological processi

  1. central nervous system development Source: Ensembl
  2. heart development Source: Ensembl
  3. lactation Source: Ensembl
  4. limb development Source: Ensembl
  5. long-chain fatty acid metabolic process Source: Ensembl
  6. maternal process involved in female pregnancy Source: Ensembl
  7. odontogenesis Source: Ensembl
  8. ovulation cycle process Source: Ensembl
  9. peptide amidation Source: Ensembl
  10. protein amidation Source: Ensembl
  11. protein homooligomerization Source: Ensembl
  12. regulation of actin cytoskeleton organization Source: Ensembl
  13. regulation of protein secretion Source: Ensembl
  14. regulation of transcription from RNA polymerase II promoter Source: Ensembl
  15. response to copper ion Source: Ensembl
  16. response to drug Source: Ensembl
  17. response to estradiol Source: Ensembl
  18. response to glucocorticoid Source: Ensembl
  19. response to hypoxia Source: Ensembl
  20. response to pH Source: Ensembl
  21. toxin metabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Peptidyl-glycine alpha-amidating monooxygenaseImported
Gene namesi
Name:PAMImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:8596. PAM.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. extracellular space Source: Ensembl
  3. neuron projection Source: Ensembl
  4. perikaryon Source: Ensembl
  5. perinuclear region of cytoplasm Source: Ensembl
  6. plasma membrane Source: Ensembl
  7. secretory granule membrane Source: Ensembl
  8. trans-Golgi network Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD6RCD5.
ExpressionAtlasiD6RCD5. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00730000111058.

Sequencei

Sequence statusi: Fragment.

D6RCD5 [UniParc]FASTAAdd to Basket

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MAGRVPSLLV LLVFPSSCLA FRSPLSVFKR FKETTRPFSN ECLGTTRPVV

PID
Length:53
Mass (Da):5,882
Last modified:July 13, 2010 - v1
Checksum:i32B2CEBFD2D4ECD5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei53 – 531Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008501 Genomic DNA. No translation available.
AC008779 Genomic DNA. No translation available.
AC010250 Genomic DNA. No translation available.
AC113373 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000509832; ENSP00000423763; ENSG00000145730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008501 Genomic DNA. No translation available.
AC008779 Genomic DNA. No translation available.
AC010250 Genomic DNA. No translation available.
AC113373 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000509832 ; ENSP00000423763 ; ENSG00000145730 .

Organism-specific databases

HGNCi HGNC:8596. PAM.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00730000111058.

Miscellaneous databases

ChiTaRSi PAM. human.
NextBioi 35493824.

Gene expression databases

Bgeei D6RCD5.
ExpressionAtlasi D6RCD5. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RCD5_HUMAN
AccessioniPrimary (citable) accession number: D6RCD5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3