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Protein
Submitted name:

Potassium channel subfamily K member 16

Gene

KCNK16

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel subfamily K member 16Imported
Gene namesi
Name:KCNK16Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000095981.10
HGNCiHGNC:14464 KCNK16

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei28 – 49HelicalSequence analysisAdd BLAST22
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Transmembranei101 – 125HelicalSequence analysisAdd BLAST25
Transmembranei137 – 155HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000095981

PTM / Processingi

Proteomic databases

PRIDEiD6RC57

Expressioni

Gene expression databases

BgeeiENSG00000095981
ExpressionAtlasiD6RC57 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RC57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 82Ion_trans_2InterPro annotationAdd BLAST60
Domaini116 – 156Ion_trans_2InterPro annotationAdd BLAST41

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00760000118858
HOGENOMiHOG000074161

Family and domain databases

InterProiView protein in InterPro
IPR003280 2pore_dom_K_chnl
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF07885 Ion_trans_2, 2 hits
PRINTSiPR01333 2POREKCHANEL

Sequencei

Sequence statusi: Complete.

D6RC57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQFVQVIME AWVKGVNPKG NSTNPSNWDF GSSFFFAGTV VTTIGYGNLA
60 70 80 90 100
PSTEAGQVFC VFYALLGIPL NVIFLNHLGT GLRAHLAAIE RWEDRPRRSQ
110 120 130 140 150
VLQVLGLALF LTLGTLVILI FPPMVFSHVE GWSFSEGFYF AFITLSTIGF
160 170 180 190
GDYVVGLRQG CGAKAAPGRR PRRGSTAARG VQVTPQDFPI SKKGLGS
Length:197
Mass (Da):21,391
Last modified:July 13, 2010 - v1
Checksum:iC689FE5B0531D2BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136087 Genomic DNA No translation available.
RefSeqiXP_011513237.1, XM_011514935.2
UniGeneiHs.287765

Genome annotation databases

EnsembliENST00000507712; ENSP00000423842; ENSG00000095981
GeneIDi83795
UCSCiuc063ohx.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RC57_HUMAN
AccessioniPrimary (citable) accession number: D6RC57
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: May 23, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health