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Protein
Submitted name:

Nuclear factor NF-kappa-B p105 subunit

Gene

NFKB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiD6RC45.

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor NF-kappa-B p105 subunitImported
Gene namesi
Name:NFKB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:7794. NFKB1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiD6RC45.
PeptideAtlasiD6RC45.

Expressioni

Gene expression databases

BgeeiENSG00000109320.
ExpressionAtlasiD6RC45. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000226574.

Structurei

3D structure databases

ProteinModelPortaliD6RC45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 145106RHD (Rel-like)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00500000044765.

Family and domain databases

Gene3Di2.60.40.340. 1 hit.
InterProiIPR030503. NF-kB_p105.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030492. RHD_CS.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF9. PTHR24169:SF9. 1 hit.
PfamiPF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RC45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDDPYLGR PEQMFHLDPS LTHTIFNPEV FQPQMALPTA DGPYLQILEQ
60 70 80 90 100
PKQRGFRFRY VCEGPSHGGL PGASSEKNKK SYPQVKICNY VGPAKVIVQL
110 120 130 140
VTNGKNIHLH AHSLVGKHCE DGICTVTAGP KDMVVGFANL GILHV
Length:145
Mass (Da):15,932
Last modified:February 17, 2016 - v7
Checksum:i48E58B78433BA485
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei145 – 1451Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF213884 Genomic DNA. No translation available.
KF457798 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000509165; ENSP00000423877; ENSG00000109320.
UCSCiuc062yom.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF213884 Genomic DNA. No translation available.
KF457798 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RC45.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000226574.

Proteomic databases

PaxDbiD6RC45.
PeptideAtlasiD6RC45.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000509165; ENSP00000423877; ENSG00000109320.
UCSCiuc062yom.1. human.

Organism-specific databases

HGNCiHGNC:7794. NFKB1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00500000044765.

Enzyme and pathway databases

SignaLinkiD6RC45.

Miscellaneous databases

ChiTaRSiNFKB1. human.

Gene expression databases

BgeeiENSG00000109320.
ExpressionAtlasiD6RC45. baseline and differential.

Family and domain databases

Gene3Di2.60.40.340. 1 hit.
InterProiIPR030503. NF-kB_p105.
IPR000451. NFkB/Dor.
IPR008967. p53-like_TF_DNA-bd.
IPR030492. RHD_CS.
IPR011539. RHD_DNA_bind_dom.
[Graphical view]
PANTHERiPTHR24169. PTHR24169. 1 hit.
PTHR24169:SF9. PTHR24169:SF9. 1 hit.
PfamiPF00554. RHD_DNA_bind. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01204. REL_1. 1 hit.
PS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD6RC45_HUMAN
AccessioniPrimary (citable) accession number: D6RC45
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: February 17, 2016
Last modified: September 7, 2016
This is version 48 of the entry and version 7 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.