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D6RBW4

- D6RBW4_HUMAN

UniProt

D6RBW4 - D6RBW4_HUMAN

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Protein
Submitted name: Inactive caspase-12
Gene
CASP12
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. cysteine-type endopeptidase activity Source: InterPro

GO - Biological processi

  1. apoptotic process Source: InterPro
  2. regulation of apoptotic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Inactive caspase-12Imported
Gene namesi
Name:CASP12Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:19004. CASP12.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiD6RBW4.
BgeeiD6RBW4.

Structurei

3D structure databases

ProteinModelPortaliD6RBW4.
SMRiD6RBW4. Positions 75-295.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotation
Contains CARD domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000234399.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiIPR001315. CARD.
IPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
IPR002138. Pept_C14_p10.
IPR015917. Pept_C14A_p45_core.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
PF00656. Peptidase_C14. 1 hit.
[Graphical view]
PRINTSiPR00376. IL1BCENZYME.
SMARTiSM00115. CASc. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6RBW4-1 [UniParc]FASTAAdd to Basket

« Hide

MADEKPSNGV LVHMVKLLIK TFLDGIFDDL MENNVLNTDE IHLIGKCLKF    50
VVSNAENLVD DITETAQTAG KIFREHLWNS KKQLSSDISS DGEREANMPG 100
LNIRNKEFNY LHNRNGSELD LLGMRDLLEN LGYSVVIKEN LTAQEMETAL 150
RQFAAHPEHQ SSDSTFLVFM SHSILNGICG TKHWDQEPDV LHDDTIFEIF 200
NNRNCQSLKD KPKMVLGLFG SPLTVEKPVQ ILMVGSCKVT SVMMLLQRLM 250
WKRTSLLSNL PHHVQHSFET PNILTQLPTI ERLSMTRYFY LFPGN 295
Length:295
Mass (Da):33,616
Last modified:July 13, 2010 - v1
Checksum:i34D83CB9CBAA4488
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002004 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000441710; ENSP00000423970; ENSG00000204403.
UCSCiuc031qdt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002004 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RBW4.
SMRi D6RBW4. Positions 75-295.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000441710 ; ENSP00000423970 ; ENSG00000204403 .
UCSCi uc031qdt.1. human.

Organism-specific databases

HGNCi HGNC:19004. CASP12.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000234399.

Miscellaneous databases

NextBioi 35493681.

Gene expression databases

ArrayExpressi D6RBW4.
Bgeei D6RBW4.

Family and domain databases

Gene3Di 1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProi IPR001315. CARD.
IPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
IPR002138. Pept_C14_p10.
IPR015917. Pept_C14A_p45_core.
[Graphical view ]
Pfami PF00619. CARD. 1 hit.
PF00656. Peptidase_C14. 1 hit.
[Graphical view ]
PRINTSi PR00376. IL1BCENZYME.
SMARTi SM00115. CASc. 1 hit.
[Graphical view ]
SUPFAMi SSF47986. SSF47986. 1 hit.
PROSITEi PS50209. CARD. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RBW4_HUMAN
AccessioniPrimary (citable) accession number: D6RBW4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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