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Protein
Submitted name:

Mothers against decapentaplegic homolog 1

Gene

SMAD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mothers against decapentaplegic homolog 1Imported
Gene namesi
Name:SMAD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:6767. SMAD1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170365.

PTM / Processingi

Proteomic databases

MaxQBiD6RBH9.
PaxDbiD6RBH9.
PeptideAtlasiD6RBH9.
PRIDEiD6RBH9.

Expressioni

Gene expression databases

BgeeiENSG00000170365.
ExpressionAtlasiD6RBH9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000305769.

Structurei

3D structure databases

ProteinModelPortaliD6RBH9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 58MH1 (MAD homology 1)InterPro annotationAdd BLAST47

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.

Family and domain databases

Gene3Di3.90.520.10. 1 hit.
InterProiIPR013790. Dwarfin.
IPR013019. MAD_homology_MH1.
[Graphical view]
PANTHERiPTHR13703. PTHR13703. 1 hit.
SUPFAMiSSF56366. SSF56366. 1 hit.
PROSITEiPS51075. MH1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D6RBH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE

LEKALSCP
Length:58
Mass (Da):6,524
Last modified:July 13, 2010 - v1
Checksum:iD61167FA7295E68C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei58Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093796 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000503324; ENSP00000422706; ENSG00000170365.
UCSCiuc062zzp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093796 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliD6RBH9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000305769.

Proteomic databases

MaxQBiD6RBH9.
PaxDbiD6RBH9.
PeptideAtlasiD6RBH9.
PRIDEiD6RBH9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000503324; ENSP00000422706; ENSG00000170365.
UCSCiuc062zzp.1. human.

Organism-specific databases

HGNCiHGNC:6767. SMAD1.
OpenTargetsiENSG00000170365.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.

Gene expression databases

BgeeiENSG00000170365.
ExpressionAtlasiD6RBH9. baseline and differential.

Family and domain databases

Gene3Di3.90.520.10. 1 hit.
InterProiIPR013790. Dwarfin.
IPR013019. MAD_homology_MH1.
[Graphical view]
PANTHERiPTHR13703. PTHR13703. 1 hit.
SUPFAMiSSF56366. SSF56366. 1 hit.
PROSITEiPS51075. MH1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD6RBH9_HUMAN
AccessioniPrimary (citable) accession number: D6RBH9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: November 2, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.