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Protein
Submitted name:

Protocadherin-1

Gene

PCDH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin-1Imported
Gene namesi
Name:PCDH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:8655. PCDH1.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000156453.

PTM / Processingi

Proteomic databases

MaxQBiD6RAX3.
PaxDbiD6RAX3.
PeptideAtlasiD6RAX3.
PRIDEiD6RAX3.

Expressioni

Gene expression databases

BgeeiENSG00000156453.
ExpressionAtlasiD6RAX3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliD6RAX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini190 – 278CAInterPro annotationAdd BLAST89

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiENOG410II7Q. Eukaryota.
ENOG410XPHP. LUCA.
GeneTreeiENSGT00890000139339.
HOGENOMiHOG000186073.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
PfamiView protein in Pfam
PF00028. Cadherin. 1 hit.
PF08266. Cadherin_2. 1 hit.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 1 hit.
SUPFAMiSSF49313. SSF49313. 2 hits.
PROSITEiView protein in PROSITE
PS00232. CADHERIN_1. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RAX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSGAGGRRC PEAALLILGP PRMEHLRHSP GPGGQRLLLP SMLLALLLLL
60 70 80 90 100
APSPGHATRV VYKVPEEQPP NTLIGSLAAD YGFPDVGHLY KLEVGAPYLR
110 120 130 140 150
VDGKTGDIFT TETSIDREGL RECQNQLPGD PCILEFEVSI TDLVQNGSPR
160 170 180 190 200
LLEGQIEVQD INDNTPNFAS PVITLAIPEN TNIGSLFPIP LASDRDAGPN
210 220 230 240 250
GVASYELQAG PEAQELFGLQ VAEDQEEKQP QLIVMGNLDR ERWDSYDLTI
260 270 280 290 300
KVQDGGSPPR ASSALLRVTV LDTNDNAPKF ERPSYEAELS ENSPIGHSVI
310 320 330 340 350
QLPHRRVTFS ATSQAQELQD PSQHSYYDSG LEESETPSSK SSSGPRLGPL
360 370 380
ALPEDHYERT TPDGSIGEME HPENEPAGRS RP
Length:382
Mass (Da):41,443
Last modified:July 13, 2010 - v1
Checksum:i189564EA26108364
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094107 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000503492; ENSP00000424667; ENSG00000156453.
UCSCiuc063icv.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RAX3_HUMAN
AccessioniPrimary (citable) accession number: D6RAX3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported