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Protein
Submitted name:

Protocadherin-1

Gene

PCDH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin-1Imported
Gene namesi
Name:PCDH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000156453.13
HGNCiHGNC:8655 PCDH1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000156453

PTM / Processingi

Proteomic databases

MaxQBiD6RAX3
PeptideAtlasiD6RAX3
PRIDEiD6RAX3

Expressioni

Gene expression databases

BgeeiENSG00000156453
ExpressionAtlasiD6RAX3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RAX3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini190 – 278CAInterPro annotationAdd BLAST89

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiENOG410II7Q Eukaryota
ENOG410XPHP LUCA
GeneTreeiENSGT00920000148958
HOGENOMiHOG000186073

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
PfamiView protein in Pfam
PF00028 Cadherin, 1 hit
PF08266 Cadherin_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 1 hit
SUPFAMiSSF49313 SSF49313, 2 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit

Sequencei

Sequence statusi: Complete.

D6RAX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSGAGGRRC PEAALLILGP PRMEHLRHSP GPGGQRLLLP SMLLALLLLL
60 70 80 90 100
APSPGHATRV VYKVPEEQPP NTLIGSLAAD YGFPDVGHLY KLEVGAPYLR
110 120 130 140 150
VDGKTGDIFT TETSIDREGL RECQNQLPGD PCILEFEVSI TDLVQNGSPR
160 170 180 190 200
LLEGQIEVQD INDNTPNFAS PVITLAIPEN TNIGSLFPIP LASDRDAGPN
210 220 230 240 250
GVASYELQAG PEAQELFGLQ VAEDQEEKQP QLIVMGNLDR ERWDSYDLTI
260 270 280 290 300
KVQDGGSPPR ASSALLRVTV LDTNDNAPKF ERPSYEAELS ENSPIGHSVI
310 320 330 340 350
QLPHRRVTFS ATSQAQELQD PSQHSYYDSG LEESETPSSK SSSGPRLGPL
360 370 380
ALPEDHYERT TPDGSIGEME HPENEPAGRS RP
Length:382
Mass (Da):41,443
Last modified:July 13, 2010 - v1
Checksum:i189564EA26108364
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094107 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000503492; ENSP00000424667; ENSG00000156453
UCSCiuc063icv.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RAX3_HUMAN
AccessioniPrimary (citable) accession number: D6RAX3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: June 20, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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