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Protein
Submitted name:

C-terminal-binding protein 1

Gene

CTBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
C-terminal-binding protein 1Imported
Gene namesi
Name:CTBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000159692.15
HGNCiHGNC:2494 CTBP1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000159692

PTM / Processingi

Proteomic databases

EPDiD6RAX2
PeptideAtlasiD6RAX2
PRIDEiD6RAX2

Expressioni

Gene expression databases

BgeeiENSG00000159692
ExpressionAtlasiD6RAX2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD6RAX2
SMRiD6RAX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 1622-Hacid_dhInterPro annotationAdd BLAST131
Domaini128 – 1852-Hacid_dh_CInterPro annotationAdd BLAST58

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0067 Eukaryota
COG0111 LUCA
GeneTreeiENSGT00530000063021
HOGENOMiHOG000136701

Family and domain databases

InterProiView protein in InterPro
IPR006139 D-isomer_2_OHA_DH_cat_dom
IPR006140 D-isomer_DH_NAD-bd
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF00389 2-Hacid_dh, 1 hit
PF02826 2-Hacid_dh_C, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Fragment.

D6RAX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCRRLSDGVR PPIMNGPLHP RPLVALLDGR DCTVEMPILK DVATVAFCDA
60 70 80 90 100
QSTQEIHEKV LNEAVGALMY HTITLTREDL EKFKALRIIV RIGSGFDNID
110 120 130 140 150
IKSAGDLGIA VCNVPAASVE ETADSTLCHI LNLYRRATWL HQALREGTRV
160 170 180
QSVEQIREVA SGAARIRGET LGIIGLGRVG QAVALR
Length:186
Mass (Da):20,275
Last modified:October 5, 2016 - v8
Checksum:iE4172BC7DB8BAF16
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei186Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092535 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000506180; ENSP00000424684; ENSG00000159692
UCSCiuc062uke.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RAX2_HUMAN
AccessioniPrimary (citable) accession number: D6RAX2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 55 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health