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D6RAQ6

- D6RAQ6_HUMAN

UniProt

D6RAQ6 - D6RAQ6_HUMAN

Protein
Submitted name:

Inactive caspase-12

Gene

CASP12

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (13 Jul 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cysteine-type endopeptidase activity Source: InterPro

    GO - Biological processi

    1. apoptotic process Source: InterPro
    2. regulation of apoptotic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Inactive caspase-12Imported
    Gene namesi
    Name:CASP12Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:19004. CASP12.

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiD6RAQ6.
    BgeeiD6RAQ6.

    Structurei

    3D structure databases

    ProteinModelPortaliD6RAQ6.
    SMRiD6RAQ6. Positions 100-143.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains CARD domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000234399.

    Family and domain databases

    Gene3Di1.10.533.10. 1 hit.
    3.40.50.1460. 1 hit.
    InterProiIPR001315. CARD.
    IPR029030. Caspase-like_dom.
    IPR011029. DEATH-like_dom.
    IPR001309. Pept_C14_ICE_p20.
    IPR002138. Pept_C14_p10.
    IPR015917. Pept_C14A_p45_core.
    [Graphical view]
    PfamiPF00619. CARD. 1 hit.
    [Graphical view]
    PRINTSiPR00376. IL1BCENZYME.
    SUPFAMiSSF47986. SSF47986. 1 hit.
    PROSITEiPS50209. CARD. 1 hit.
    PS50207. CASPASE_P10. 1 hit.
    PS50208. CASPASE_P20. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D6RAQ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADEKPSNGV LVHMVKLLIK TFLDGIFDDL MENNVLNTDE IHLIGKCLKF    50
    VVSNAENLVD DITETAQTAG KIFREHLWNS KKQLSSDISS DGEREANMPG 100
    LNIRNKEFNY LHNRNGSELD LLGMRDLLEN LGYSVVIKEN LTAQMVLGLF 150
    GSPLTVEKPV QILMVGSCKV TSVMMLLQRL MWKRTSLLSN LPHHVQHSFE 200
    TPNILTQLPT IERLSMTRYF YLFPGN 226
    Length:226
    Mass (Da):25,647
    Last modified:July 13, 2010 - v1
    Checksum:i700A271C9E72F6CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP002004 Genomic DNA. No translation available.
    KF459667 Genomic DNA. No translation available.
    KF495790 Genomic DNA. No translation available.
    KF495792 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000494737; ENSP00000421815; ENSG00000204403.
    UCSCiuc031qdu.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP002004 Genomic DNA. No translation available.
    KF459667 Genomic DNA. No translation available.
    KF495790 Genomic DNA. No translation available.
    KF495792 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali D6RAQ6.
    SMRi D6RAQ6. Positions 100-143.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000494737 ; ENSP00000421815 ; ENSG00000204403 .
    UCSCi uc031qdu.1. human.

    Organism-specific databases

    HGNCi HGNC:19004. CASP12.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000234399.

    Miscellaneous databases

    NextBioi 35493328.

    Gene expression databases

    ArrayExpressi D6RAQ6.
    Bgeei D6RAQ6.

    Family and domain databases

    Gene3Di 1.10.533.10. 1 hit.
    3.40.50.1460. 1 hit.
    InterProi IPR001315. CARD.
    IPR029030. Caspase-like_dom.
    IPR011029. DEATH-like_dom.
    IPR001309. Pept_C14_ICE_p20.
    IPR002138. Pept_C14_p10.
    IPR015917. Pept_C14A_p45_core.
    [Graphical view ]
    Pfami PF00619. CARD. 1 hit.
    [Graphical view ]
    PRINTSi PR00376. IL1BCENZYME.
    SUPFAMi SSF47986. SSF47986. 1 hit.
    PROSITEi PS50209. CARD. 1 hit.
    PS50207. CASPASE_P10. 1 hit.
    PS50208. CASPASE_P20. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiD6RAQ6_HUMAN
    AccessioniPrimary (citable) accession number: D6RAQ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 13, 2010
    Last sequence update: July 13, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3