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D6RAQ6

- D6RAQ6_HUMAN

UniProt

D6RAQ6 - D6RAQ6_HUMAN

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Protein
Submitted name:

Inactive caspase-12

Gene
CASP12
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. cysteine-type endopeptidase activity Source: InterPro

GO - Biological processi

  1. apoptotic process Source: InterPro
  2. regulation of apoptotic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Inactive caspase-12Imported
Gene namesi
Name:CASP12Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:19004. CASP12.

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiD6RAQ6.
BgeeiD6RAQ6.

Structurei

3D structure databases

ProteinModelPortaliD6RAQ6.
SMRiD6RAQ6. Positions 100-143.

Family & Domainsi

Sequence similaritiesi

Contains CARD domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000234399.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiIPR001315. CARD.
IPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR001309. Pept_C14_ICE_p20.
IPR002138. Pept_C14_p10.
IPR015917. Pept_C14A_p45_core.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
[Graphical view]
PRINTSiPR00376. IL1BCENZYME.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D6RAQ6-1 [UniParc]FASTAAdd to Basket

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MADEKPSNGV LVHMVKLLIK TFLDGIFDDL MENNVLNTDE IHLIGKCLKF    50
VVSNAENLVD DITETAQTAG KIFREHLWNS KKQLSSDISS DGEREANMPG 100
LNIRNKEFNY LHNRNGSELD LLGMRDLLEN LGYSVVIKEN LTAQMVLGLF 150
GSPLTVEKPV QILMVGSCKV TSVMMLLQRL MWKRTSLLSN LPHHVQHSFE 200
TPNILTQLPT IERLSMTRYF YLFPGN 226
Length:226
Mass (Da):25,647
Last modified:July 13, 2010 - v1
Checksum:i700A271C9E72F6CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002004 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000494737; ENSP00000421815; ENSG00000204403.
UCSCiuc031qdu.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP002004 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali D6RAQ6.
SMRi D6RAQ6. Positions 100-143.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000494737 ; ENSP00000421815 ; ENSG00000204403 .
UCSCi uc031qdu.1. human.

Organism-specific databases

HGNCi HGNC:19004. CASP12.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000234399.

Miscellaneous databases

NextBioi 35493328.

Gene expression databases

ArrayExpressi D6RAQ6.
Bgeei D6RAQ6.

Family and domain databases

Gene3Di 1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProi IPR001315. CARD.
IPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR001309. Pept_C14_ICE_p20.
IPR002138. Pept_C14_p10.
IPR015917. Pept_C14A_p45_core.
[Graphical view ]
Pfami PF00619. CARD. 1 hit.
[Graphical view ]
PRINTSi PR00376. IL1BCENZYME.
SUPFAMi SSF47986. SSF47986. 1 hit.
PROSITEi PS50209. CARD. 1 hit.
PS50207. CASPASE_P10. 1 hit.
PS50208. CASPASE_P20. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD6RAQ6_HUMAN
AccessioniPrimary (citable) accession number: D6RAQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: July 9, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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