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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2 D3

Gene

UBE2D3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2 D3Imported
Gene namesi
Name:UBE2D3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000109332.19.
HGNCiHGNC:12476. UBE2D3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000109332.

PTM / Processingi

Proteomic databases

MaxQBiD6RAH7.

Expressioni

Gene expression databases

BgeeiENSG00000109332.
ExpressionAtlasiD6RAH7. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 107UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
GeneTreeiENSGT00760000119012.
HOGENOMiHOG000233455.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D6RAH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN
60 70 80 90 100
SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT
110
DRDKYNRISR EWTQKYAM
Length:118
Mass (Da):13,637
Last modified:July 13, 2010 - v1
Checksum:iA74F8C7199FE8085
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018797 Genomic DNA. No translation available.
RefSeqiNP_001287724.1. NM_001300795.1.
XP_016864073.1. XM_017008584.1.
UniGeneiHs.518773.
Hs.595430.
Hs.621366.

Genome annotation databases

EnsembliENST00000502404; ENSP00000421904; ENSG00000109332.
ENST00000504211; ENSP00000426620; ENSG00000109332.
ENST00000505207; ENSP00000426586; ENSG00000109332.
ENST00000507845; ENSP00000424359; ENSG00000109332.
GeneIDi7323.
UCSCiuc062ypc.1. human.

Similar proteinsi

Entry informationi

Entry nameiD6RAH7_HUMAN
AccessioniPrimary (citable) accession number: D6RAH7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: September 27, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported