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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2 D3

Gene

UBE2D3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2 D3Imported
Gene namesi
Name:UBE2D3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000109332.19
HGNCiHGNC:12476 UBE2D3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000109332

PTM / Processingi

Proteomic databases

MaxQBiD6RAH7
PeptideAtlasiD6RAH7

Expressioni

Gene expression databases

BgeeiENSG00000109332

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 107UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0417 Eukaryota
COG5078 LUCA
GeneTreeiENSGT00910000143990
HOGENOMiHOG000233455

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

D6RAH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN
60 70 80 90 100
SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT
110
DRDKYNRISR EWTQKYAM
Length:118
Mass (Da):13,637
Last modified:July 13, 2010 - v1
Checksum:iA74F8C7199FE8085
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018797 Genomic DNA No translation available.
RefSeqiNP_001287724.1, NM_001300795.1
XP_016864073.1, XM_017008584.1
UniGeneiHs.518773
Hs.595430
Hs.621366

Genome annotation databases

EnsembliENST00000502404; ENSP00000421904; ENSG00000109332
ENST00000504211; ENSP00000426620; ENSG00000109332
ENST00000505207; ENSP00000426586; ENSG00000109332
ENST00000507845; ENSP00000424359; ENSG00000109332
GeneIDi7323
UCSCiuc062ypc.1 human

Similar proteinsi

Entry informationi

Entry nameiD6RAH7_HUMAN
AccessioniPrimary (citable) accession number: D6RAH7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 13, 2010
Last sequence update: July 13, 2010
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health